Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 264707..265446 Replicon chromosome
Accession NZ_CP019706
Organism Pantoea alhagi strain LTYR-11Z

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag B1H58_RS01210 Protein ID WP_085067603.1
Coordinates 264707..265192 (-) Length 162 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag B1H58_RS01215 Protein ID WP_085067604.1
Coordinates 265180..265446 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B1H58_RS20530 260563..261114 - 552 WP_157130129.1 replication initiation negative regulator SeqA -
B1H58_RS01185 261367..262131 + 765 WP_085067600.1 esterase -
B1H58_RS01190 262286..262561 + 276 WP_085072204.1 LexA regulated protein -
B1H58_RS01195 262701..263231 + 531 WP_085067601.1 flavodoxin FldA -
B1H58_RS01200 263593..264036 + 444 WP_085067602.1 ferric iron uptake transcriptional regulator -
B1H58_RS01205 264118..264435 - 318 Protein_237 ChiP family protein -
B1H58_RS01210 264707..265192 - 486 WP_085067603.1 GNAT family N-acetyltransferase Toxin
B1H58_RS01215 265180..265446 - 267 WP_085067604.1 DUF1778 domain-containing protein Antitoxin
B1H58_RS01220 265628..265924 - 297 WP_085067605.1 chorismate mutase -
B1H58_RS01225 266518..266883 + 366 WP_085072205.1 hypothetical protein -
B1H58_RS01230 266894..268993 + 2100 WP_085067606.1 pyrroloquinoline quinone-dependent dehydrogenase -
B1H58_RS01235 269596..269922 + 327 WP_085067607.1 four-helix bundle copper-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(28-152)

Antitoxin

Vibrio phage ICP1, Orf50

(6-82)


Sequences

Toxin        


Download         Length: 162 a.a.        Molecular weight: 17880.65 Da        Isoelectric Point: 10.1907

>T73200 WP_085067603.1 NZ_CP019706:c265192-264707 [Pantoea alhagi]
VGRVTAPEPLSAFHQVAEFVSSEAVLDDWLKQRGLKNQALRAARTFVVCKKDTKQIAGFYSLATGSVNHTEATGSLRRNM
PDPIPVIILARLTVDVSFRGKGLGADLLHDAVLRCYRVAENIGVRAIMVHALTEEAKNFYIYHGFKPSQTQQRTLFLKLS
Q

Download         Length: 486 bp

>T73200 NZ_CP019706:c265192-264707 [Pantoea alhagi]
GTGGGACGTGTAACAGCACCAGAACCTTTATCCGCTTTTCATCAGGTGGCGGAGTTTGTCAGCAGTGAAGCCGTGCTCGA
TGACTGGTTAAAGCAGAGGGGCCTCAAAAACCAGGCTCTCAGAGCGGCCCGAACGTTTGTGGTTTGTAAGAAGGACACTA
AACAAATAGCCGGCTTTTACTCTCTGGCCACCGGGAGCGTCAACCATACAGAAGCGACAGGCAGCCTTCGGCGTAACATG
CCTGATCCCATTCCTGTCATTATACTTGCCCGTCTGACTGTCGATGTCTCATTCCGTGGAAAAGGGCTTGGTGCCGATTT
ACTGCATGACGCAGTGCTTCGTTGCTATCGGGTAGCCGAGAATATTGGTGTACGTGCAATCATGGTTCACGCACTTACGG
AAGAAGCCAAAAACTTCTATATTTATCATGGTTTCAAACCATCACAAACTCAGCAGCGGACATTATTCCTGAAACTCTCT
CAATAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10148.62 Da        Isoelectric Point: 4.5141

>AT73200 WP_085067604.1 NZ_CP019706:c265446-265180 [Pantoea alhagi]
MKSDVQLNLRAKESQRALIDAAAEILHKSRTDFILEMACKAAENVILDRRVFNFNDEQYAEFIDMIDAPVTDDPVIEKLL
ARKPQWDV

Download         Length: 267 bp

>AT73200 NZ_CP019706:c265446-265180 [Pantoea alhagi]
ATGAAATCTGATGTTCAACTCAACCTTAGGGCCAAAGAATCTCAGCGAGCACTCATTGATGCCGCGGCTGAAATCCTTCA
CAAATCACGTACAGATTTCATTCTGGAAATGGCCTGTAAGGCTGCCGAGAATGTTATCCTCGACCGCCGCGTCTTTAATT
TTAACGATGAGCAATACGCAGAGTTCATCGATATGATTGATGCACCGGTCACAGATGATCCCGTTATCGAAAAACTGCTG
GCAAGGAAACCTCAGTGGGACGTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References