Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 3364405..3364942 Replicon chromosome
Accession NZ_CP019686
Organism Proteus sp. CD3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BTA34_RS15000 Protein ID WP_151436252.1
Coordinates 3364405..3364698 (-) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A8I0X075
Locus tag BTA34_RS15005 Protein ID WP_023583073.1
Coordinates 3364688..3364942 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTA34_RS14985 (BTA34_14995) 3360010..3362844 - 2835 WP_151436250.1 excinuclease ABC subunit UvrA -
BTA34_RS14990 (BTA34_15000) 3363096..3363623 + 528 WP_099076296.1 single-stranded DNA-binding protein SSB1 -
BTA34_RS14995 (BTA34_15005) 3363828..3364358 + 531 WP_151436251.1 zinc uptake transcriptional repressor Zur -
BTA34_RS15000 (BTA34_15010) 3364405..3364698 - 294 WP_151436252.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BTA34_RS15005 (BTA34_15015) 3364688..3364942 - 255 WP_023583073.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
BTA34_RS15010 (BTA34_15020) 3365097..3365708 - 612 WP_151436253.1 transcriptional repressor LexA -
BTA34_RS15015 (BTA34_15025) 3365836..3366207 - 372 WP_151436254.1 diacylglycerol kinase -
BTA34_RS15020 (BTA34_15030) 3366338..3368821 + 2484 WP_151436255.1 glycerol-3-phosphate 1-O-acyltransferase PlsB -
BTA34_RS15025 (BTA34_15035) 3368925..3369779 - 855 WP_151436256.1 4-hydroxybenzoate octaprenyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11355.40 Da        Isoelectric Point: 10.1687

>T73168 WP_151436252.1 NZ_CP019686:c3364698-3364405 [Proteus sp. CD3]
MIFNIEFDKRALKEWQKLDQSIKEQFKKKLKKLQENPYIESARLKGDLSGCYKIKLRASGFRLVYQIIDSEVVILVIAIG
KSEESKAYSLAEMRIQK

Download         Length: 294 bp

>T73168 NZ_CP019686:c3364698-3364405 [Proteus sp. CD3]
ATGATCTTTAATATTGAGTTTGATAAGCGTGCATTAAAAGAATGGCAGAAACTTGATCAAAGCATTAAAGAACAATTTAA
AAAGAAATTAAAAAAATTACAGGAAAACCCTTATATAGAGTCTGCTCGCTTAAAAGGTGATCTCTCGGGTTGCTATAAGA
TTAAATTACGAGCATCTGGTTTTCGATTGGTTTACCAAATCATTGATTCAGAAGTCGTTATTTTAGTTATTGCTATTGGT
AAGAGTGAAGAAAGTAAAGCGTATTCATTAGCTGAAATGAGAATTCAAAAGTAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9841.29 Da        Isoelectric Point: 4.5748

>AT73168 WP_023583073.1 NZ_CP019686:c3364942-3364688 [Proteus sp. CD3]
MTTIQVRVDDELKKEAYQVFEKMNLSPSDAIRLFLRYVSENEKLPFSEVSVVVGEQDEDEDILAVVRERLKKPCKRIRVN
IDDL

Download         Length: 255 bp

>AT73168 NZ_CP019686:c3364942-3364688 [Proteus sp. CD3]
ATGACAACAATACAAGTTAGAGTAGACGATGAGCTAAAAAAAGAAGCTTATCAAGTATTTGAAAAAATGAATCTATCTCC
TTCAGATGCTATAAGATTGTTTCTACGTTATGTTTCTGAAAATGAAAAGTTACCTTTCTCTGAAGTTTCTGTCGTTGTTG
GTGAACAAGATGAAGATGAGGATATTTTAGCTGTTGTACGTGAGCGTTTGAAGAAACCATGTAAACGTATAAGAGTAAAT
ATTGATGATCTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References