Detailed information of TA system TA073165

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tacAT/DUF1778(antitoxin)
• Location: 2162068..2162807
• Replicon: chromosome
• Accession: NZ_CP019686
• Organism: Proteus sp. CD3

Toxin (Protein)

• Gene name: tacT
• Uniprot ID: -
• Locus tag: BTA34_RS09840
• Protein ID: WP_151435480.1
• Coordinates: 2162322..2162807 (+)
• Length: 162 a.a.

Antitoxin (Protein)

• Gene name: tacA
• Uniprot ID: -
• Locus tag: BTA34_RS09835
• Protein ID: WP_151435479.1
• Coordinates: 2162068..2162334 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BTA34_RS09800 (BTA34_09785)	2157719..2158201	+	483	WP_006533151.1	flagellar basal body-associated protein FliL	-
BTA34_RS09805 (BTA34_09790)	2158207..2159238	+	1032	WP_151435474.1	flagellar motor switch protein FliM	-
BTA34_RS09810 (BTA34_09795)	2159231..2159641	+	411	WP_023581830.1	flagellar motor switch protein FliN	-
BTA34_RS09815 (BTA34_09800)	2159645..2160091	+	447	WP_151435475.1	flagellar biosynthetic protein FliO	-
BTA34_RS09820 (BTA34_09805)	2160091..2160861	+	771	WP_151435476.1	flagellar type III secretion system pore protein FliP	-
BTA34_RS09825 (BTA34_09810)	2160877..2161146	+	270	WP_151435477.1	flagellar biosynthesis protein FliQ	-
BTA34_RS09830 (BTA34_09815)	2161152..2161934	+	783	WP_151435478.1	flagellar biosynthetic protein FliR	-
BTA34_RS09835 (BTA34_09820)	2162068..2162334	+	267	WP_151435479.1	DUF1778 domain-containing protein	Antitoxin
BTA34_RS09840 (BTA34_09825)	2162322..2162807	+	486	WP_151435480.1	GNAT family N-acetyltransferase	Toxin
BTA34_RS09845 (BTA34_09830)	2162896..2163840	-	945	WP_151435481.1	flagellar hook-associated protein FlgL	-
BTA34_RS09850 (BTA34_09835)	2163868..2165508	-	1641	WP_151435482.1	flagellar hook-associated protein FlgK	-
BTA34_RS09855 (BTA34_09840)	2165626..2166612	-	987	WP_151435483.1	flagellar assembly peptidoglycan hydrolase FlgJ	-
BTA34_RS09860 (BTA34_09845)	2166612..2167718	-	1107	WP_151435484.1	flagellar basal body P-ring protein FlgI	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (28-151)

Antitoxin

• Vibrio phage ICP1, Orf50 (6-81)

Sequences

Toxin

Protein

• Length: 162 a.a.
• Molecular weight: 17823.43 Da
• Isoelectric Point: 8.9704

>T73165 WP_151435480.1 NZ_CP019686:2162322-2162807 [Proteus sp. CD3]
MGKVTAPEPLSSSHEVADFYSSEIVLDNWIKQRGFKNQLLGASRTFVVCKENSHYVVGYYSLATGSVNHTEAINSIRRNM
SDPIPVIILARLAVDISFHGKGLGADLLRDAVLRCYHVAENIGVKAIMVHSLTENAKQFYLHNGFKASSTQENTLFLALK
K

Nucleotide

• Length: 486 bp

>T73165 NZ_CP019686:2162322-2162807 [Proteus sp. CD3]
ATGGGAAAAGTAACAGCGCCTGAGCCGTTATCAAGTTCGCATGAAGTCGCTGATTTTTATAGTAGTGAAATTGTATTAGA
TAACTGGATAAAGCAAAGAGGTTTCAAAAACCAATTATTGGGTGCATCTCGTACTTTTGTGGTCTGTAAAGAAAATAGCC
ACTATGTTGTTGGCTATTATTCTTTAGCAACAGGAAGTGTTAATCATACTGAAGCCATCAACTCGATTCGTCGTAATATG
TCAGATCCAATACCTGTTATCATTTTAGCTAGACTTGCCGTCGATATCTCTTTCCATGGAAAAGGTCTTGGCGCTGATTT
ATTAAGAGATGCTGTTTTACGTTGTTATCATGTTGCTGAAAATATTGGCGTTAAAGCGATTATGGTTCATTCTCTCACAG
AAAATGCAAAACAGTTTTATCTTCATAATGGTTTTAAAGCCTCTTCAACACAAGAAAACACTTTATTTCTAGCATTAAAG
AAATGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10127.62 Da
• Isoelectric Point: 4.5256

>AT73165 WP_151435479.1 NZ_CP019686:2162068-2162334 [Proteus sp. CD3]
MKSDVQLNIRAKESQRALIDTAAEILHKSRTDFILETACQAAEDVILDRRTFNLNDAQYAEFIEIIDAPVDIDPALEKLL
MRKPLWEK

Nucleotide

• Length: 267 bp

>AT73165 NZ_CP019686:2162068-2162334 [Proteus sp. CD3]
ATGAAATCAGATGTACAACTTAATATTCGCGCTAAAGAATCACAACGCGCTCTTATTGATACTGCTGCTGAAATTCTCCA
TAAATCTCGTACTGACTTTATTCTTGAAACAGCATGTCAAGCTGCTGAGGATGTCATTTTAGACCGTCGAACCTTTAATT
TAAATGATGCTCAATATGCCGAATTTATAGAAATTATTGATGCACCGGTTGATATTGACCCTGCTCTTGAAAAGTTATTA
ATGAGAAAACCATTATGGGAAAAGTAA