Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1863786..1864585 Replicon chromosome
Accession NZ_CP019686
Organism Proteus sp. CD3

Toxin (Protein)


Gene name TacT3 Uniprot ID -
Locus tag BTA34_RS08495 Protein ID WP_151435279.1
Coordinates 1863786..1864310 (-) Length 175 a.a.

Antitoxin (Protein)


Gene name TacA3 Uniprot ID -
Locus tag BTA34_RS08500 Protein ID WP_099075495.1
Coordinates 1864307..1864585 (-) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTA34_RS08480 (BTA34_08465) 1860114..1861055 - 942 WP_151435277.1 glyoxylate/hydroxypyruvate reductase GhrA -
BTA34_RS08490 (BTA34_08475) 1862010..1863710 + 1701 WP_151435278.1 C4-dicarboxylic acid transporter DauA -
BTA34_RS08495 (BTA34_08480) 1863786..1864310 - 525 WP_151435279.1 GNAT family N-acetyltransferase Toxin
BTA34_RS08500 (BTA34_08485) 1864307..1864585 - 279 WP_099075495.1 DUF1778 domain-containing protein Antitoxin
BTA34_RS08505 (BTA34_08490) 1864738..1865667 - 930 WP_151435280.1 TIGR01212 family radical SAM protein -
BTA34_RS08510 (BTA34_08495) 1865676..1866530 - 855 WP_151435281.1 3-deoxy-8-phosphooctulonate synthase -
BTA34_RS08515 (BTA34_08500) 1866588..1867397 - 810 WP_265576330.1 invasion regulator SirB1 -
BTA34_RS08520 (BTA34_08505) 1867381..1868229 - 849 WP_100160218.1 peptide chain release factor N(5)-glutamine methyltransferase -
BTA34_RS08525 (BTA34_08510) 1868229..1869311 - 1083 WP_088495429.1 peptide chain release factor 1 -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Vibrio phage ICP1, Orf50

(4-87)


Sequences

Toxin        


Download         Length: 175 a.a.        Molecular weight: 19224.17 Da        Isoelectric Point: 9.3652

>T73164 WP_151435279.1 NZ_CP019686:c1864310-1863786 [Proteus sp. CD3]
MTIPNWHEEAISKKHDRNTFNCGDAVLNQFLYRHARQNHENGSAKTYLAINTNNNIIIGYYSLCPASIEFERTPEVIARG
LARHDIPVFRLARLATDLSVQGKGLGGQLLLAAGKRCLAVASELGGVALLIDAKNERVANWYISYGAVPLLDSPLSLLIS
FKTIYTALRMANKI

Download         Length: 525 bp

>T73164 NZ_CP019686:c1864310-1863786 [Proteus sp. CD3]
ATGACAATACCGAATTGGCATGAAGAAGCGATAAGTAAAAAGCATGATAGAAATACATTTAATTGTGGCGATGCAGTGCT
TAATCAATTCCTGTATCGTCACGCAAGACAAAATCATGAAAATGGGAGTGCTAAAACCTATTTAGCGATTAATACAAATA
ACAATATTATTATAGGCTATTACAGCTTATGTCCCGCCTCAATTGAATTCGAACGGACTCCTGAAGTGATCGCACGAGGC
TTAGCACGTCATGATATCCCTGTGTTTAGGCTTGCCCGTTTAGCAACTGACTTATCCGTTCAAGGAAAAGGGCTTGGAGG
ACAATTATTGCTTGCAGCAGGAAAACGCTGTCTTGCTGTTGCGAGTGAATTAGGCGGTGTTGCATTGCTTATAGATGCTA
AAAATGAAAGAGTCGCTAATTGGTATATTAGCTATGGAGCTGTGCCATTATTAGACTCACCTCTCTCTTTATTAATTTCC
TTCAAGACAATTTATACTGCACTGAGAATGGCAAACAAAATATGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10339.00 Da        Isoelectric Point: 6.3497

>AT73164 WP_099075495.1 NZ_CP019686:c1864585-1864307 [Proteus sp. CD3]
MAQTLVENSERVSIRITTEDKSLLVRAASLENTNLTEFVLRNIVPVARQIIENNERLKLSEKDTLRVMELLDNPPKPNAK
LLAAAFALPDKV

Download         Length: 279 bp

>AT73164 NZ_CP019686:c1864585-1864307 [Proteus sp. CD3]
ATGGCTCAAACACTTGTAGAAAACAGTGAGAGAGTATCAATTCGTATTACTACAGAAGATAAATCACTGCTTGTTCGTGC
GGCTAGTTTGGAAAATACAAACCTAACAGAGTTCGTCCTTCGTAATATCGTACCTGTCGCTCGGCAAATCATTGAAAATA
ATGAGCGTTTAAAATTATCGGAAAAAGACACATTGCGTGTTATGGAACTTTTAGATAATCCGCCAAAGCCTAATGCTAAG
TTACTTGCTGCGGCTTTTGCTTTACCGGACAAAGTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References