73163

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) sanaTA/AbiEii-DUF6088
Location 1386298..1387651 Replicon chromosome
Accession NZ_CP019686
Organism Proteus sp. CD3

Toxin (Protein)


Gene name sanaT Uniprot ID -
Locus tag BTA34_RS06325 Protein ID WP_151434922.1
Coordinates 1386298..1387263 (-) Length 322 a.a.

Antitoxin (Protein)


Gene name sanaA Uniprot ID -
Locus tag BTA34_RS06330 Protein ID WP_151434923.1
Coordinates 1387247..1387651 (-) Length 135 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTA34_RS06315 (BTA34_06315) 1383575..1384927 + 1353 WP_151434921.1 OprD family outer membrane porin -
BTA34_RS06320 (BTA34_06320) 1385335..1386213 + 879 WP_088495802.1 protease HtpX -
BTA34_RS06325 (BTA34_06325) 1386298..1387263 - 966 WP_151434922.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
BTA34_RS06330 (BTA34_06330) 1387247..1387651 - 405 WP_151434923.1 DUF6088 family protein Antitoxin
BTA34_RS06335 (BTA34_06335) 1388029..1388883 - 855 WP_265576320.1 hypothetical protein -
BTA34_RS06340 (BTA34_06340) 1389028..1390419 - 1392 WP_151434924.1 L-cystine transporter -
BTA34_RS06345 (BTA34_06345) 1390663..1391229 - 567 WP_151434925.1 metal-dependent hydrolase -
BTA34_RS06350 (BTA34_06350) 1391539..1392207 - 669 WP_151434926.1 hexitol phosphatase HxpB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-298)

Antitoxin

Protein of unknown function DUF6088

(6-132)


Sequences

Toxin        


Download         Length: 322 a.a.        Molecular weight: 37648.26 Da        Isoelectric Point: 6.8998

>T73163 WP_151434922.1 NZ_CP019686:c1387263-1386298 [Proteus sp. CD3]
MKKQIDLFPDVADALGIDSVSIVEKDFYIIELLKIIKDAAYHSHQLVFSGGTALSKSGIALNRMSEDVDIKMVPNVQFSS
KSREQRKKIRRELIGLIIKKIESLDFFKINLENAIKRDEYRYYEVEIQYPQKHQQAPCLRPFIKLEFIETELLEPPENRN
ISSLVTQLTDQGDVIESLPCATNESTHVEKLISIMRRTASLNRGYDRFDDKSLVRHIYDNYCIVTHQPPDYQKLSIFMYN
CIQQDIARYSNQYPEFCEFPLKELQLGLDRLRDDPIHEQRYLKFVLPMVFSKNKITWKNAYATFHSTASILLNILNEKYY
D

Download         Length: 966 bp

>T73163 NZ_CP019686:c1387263-1386298 [Proteus sp. CD3]
ATGAAAAAACAAATTGATTTATTCCCTGATGTTGCAGATGCTCTCGGTATTGATTCCGTATCTATTGTTGAAAAAGACTT
TTATATCATTGAGCTATTAAAAATAATTAAAGATGCAGCTTACCATTCCCATCAACTTGTTTTTTCTGGTGGTACAGCAC
TATCTAAATCAGGAATAGCATTAAACAGAATGTCTGAAGATGTTGATATAAAAATGGTACCAAATGTTCAGTTTTCATCC
AAGTCAAGGGAGCAGCGTAAAAAAATTAGGCGTGAATTAATTGGCTTAATTATAAAGAAAATAGAATCATTAGATTTTTT
TAAAATTAACTTAGAAAATGCAATTAAACGTGATGAATATCGCTACTACGAAGTAGAAATACAATACCCTCAAAAGCACC
AGCAAGCACCTTGCTTAAGACCCTTCATTAAACTTGAATTTATCGAAACAGAATTATTAGAGCCACCCGAAAATAGAAAC
ATTAGCTCATTAGTTACACAATTAACGGATCAAGGAGATGTAATTGAATCACTTCCATGTGCTACAAATGAATCAACTCA
TGTGGAGAAACTTATATCAATAATGCGTAGAACAGCATCATTAAATCGTGGTTATGATCGATTTGACGATAAATCATTAG
TTAGGCATATTTATGATAATTATTGTATTGTCACTCACCAACCACCTGATTATCAAAAACTCAGTATTTTTATGTATAAC
TGTATACAACAAGATATAGCACGATACTCAAACCAGTATCCTGAATTTTGCGAGTTTCCACTTAAAGAATTGCAACTAGG
GCTAGATAGATTACGTGATGACCCAATTCATGAGCAACGTTATCTAAAATTTGTTTTACCGATGGTCTTTAGCAAAAACA
AAATCACATGGAAAAATGCATATGCAACATTTCATTCAACAGCCTCTATTTTATTAAATATCCTTAACGAAAAATATTAT
GATTAA

Antitoxin


Download         Length: 135 a.a.        Molecular weight: 15069.51 Da        Isoelectric Point: 10.9154

>AT73163 WP_151434923.1 NZ_CP019686:c1387651-1387247 [Proteus sp. CD3]
MTIKDKIETRLKRSKRNVFFRKDFNDIAGYDQIGRVLNLLIQEGVLLRVGQGVYTKARRNQITGKTMPAAPGGSASVIIE
TLDRLKIPYLLGDATKAYNEGSSTQIPAYVEIKTPRRFSRKLIIGNSKINEKTN

Download         Length: 405 bp

>AT73163 NZ_CP019686:c1387651-1387247 [Proteus sp. CD3]
ATGACAATAAAAGATAAAATTGAAACACGTTTAAAACGTTCAAAACGTAATGTTTTCTTTCGTAAAGATTTTAATGATAT
AGCAGGTTATGATCAAATAGGTCGGGTTTTAAACTTACTTATCCAAGAAGGTGTTTTGCTAAGAGTTGGGCAAGGTGTTT
ATACCAAAGCCCGCCGTAACCAAATTACAGGAAAAACAATGCCAGCAGCCCCTGGTGGGTCAGCATCAGTTATTATTGAA
ACACTTGATCGTCTCAAAATACCTTATTTACTTGGTGATGCCACCAAAGCATACAATGAGGGTAGTTCAACTCAAATTCC
TGCATATGTTGAAATAAAAACCCCTCGTCGTTTTAGCCGAAAACTCATAATAGGGAATAGCAAAATTAATGAAAAAACAA
ATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References