73161

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 478555..479194 Replicon chromosome
Accession NZ_CP019686
Organism Proteus sp. CD3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BTA34_RS02105 Protein ID WP_151434306.1
Coordinates 478555..478959 (-) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BTA34_RS02110 Protein ID WP_099074198.1
Coordinates 478952..479194 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTA34_RS02080 (BTA34_02085) 474361..474831 + 471 WP_036932916.1 6,7-dimethyl-8-ribityllumazine synthase -
BTA34_RS02085 (BTA34_02090) 474860..475273 + 414 WP_006535124.1 transcription antitermination factor NusB -
BTA34_RS02090 (BTA34_02095) 475377..476360 + 984 WP_151434303.1 thiamine-phosphate kinase -
BTA34_RS02095 (BTA34_02100) 476423..477319 - 897 WP_151434304.1 hypothetical protein -
BTA34_RS02100 (BTA34_02105) 477780..478115 - 336 WP_151434305.1 zinc ribbon domain-containing protein YjdM -
BTA34_RS02105 (BTA34_02110) 478555..478959 - 405 WP_151434306.1 type II toxin-antitoxin system VapC family toxin Toxin
BTA34_RS02110 (BTA34_02115) 478952..479194 - 243 WP_099074198.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
BTA34_RS02115 (BTA34_02120) 479324..480331 - 1008 WP_265576156.1 ribose operon transcriptional repressor RbsR -
BTA34_RS02120 (BTA34_02125) 480336..481262 - 927 WP_151434307.1 ribokinase -
BTA34_RS02125 (BTA34_02130) 481341..482231 - 891 WP_151434308.1 ribose ABC transporter substrate-binding protein RbsB -
BTA34_RS02130 (BTA34_02135) 482274..483239 - 966 WP_069368591.1 ribose ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-125)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 15304.51 Da        Isoelectric Point: 7.5228

>T73161 WP_151434306.1 NZ_CP019686:c478959-478555 [Proteus sp. CD3]
MIKYLLDTNIVIFTIKRRPEFLLPKFNQHAEQLAISTITLAELVFGAEKSLNSTKNLATVNDFVSRLTVLSYDELAAFHY
GDIRATLEKQGKRIGDNELHIAAHARSKGLIVVTNNTREFERVDGLRIEDWTHH

Download         Length: 405 bp

>T73161 NZ_CP019686:c478959-478555 [Proteus sp. CD3]
ATGATTAAATACCTGTTAGATACAAACATCGTTATATTTACCATTAAACGCAGACCTGAGTTTTTGCTACCGAAATTTAA
TCAACATGCAGAACAATTAGCTATTTCTACAATCACACTCGCTGAGCTAGTTTTTGGTGCTGAAAAAAGTTTAAATTCAA
CTAAAAACTTAGCTACAGTTAACGACTTTGTTTCTCGACTCACTGTTTTATCTTACGATGAGCTAGCCGCTTTTCATTAC
GGAGATATAAGAGCAACACTTGAGAAACAAGGAAAACGCATTGGTGATAATGAGTTACACATAGCAGCACATGCTAGAAG
TAAAGGGCTAATCGTAGTGACAAATAATACTCGAGAATTTGAAAGAGTTGATGGATTAAGGATTGAGGATTGGACTCATC
ATTAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9378.43 Da        Isoelectric Point: 4.6028

>AT73161 WP_099074198.1 NZ_CP019686:c479194-478952 [Proteus sp. CD3]
MIQHGKVFMSNRTQNVRLPAETRFPDDVKEVFVRVKGKERIITPIQNAWDSFFLSDQSVTDDFLSERPDQVTSERESFDD

Download         Length: 243 bp

>AT73161 NZ_CP019686:c479194-478952 [Proteus sp. CD3]
ATGATCCAGCATGGCAAAGTATTTATGAGCAATAGAACACAAAATGTTCGTTTACCCGCTGAGACTCGATTTCCTGATGA
TGTAAAAGAAGTTTTTGTTCGCGTCAAAGGAAAAGAAAGAATAATCACACCTATACAAAATGCATGGGATAGCTTTTTCT
TATCAGATCAGTCTGTAACAGATGATTTTTTATCTGAAAGACCTGATCAAGTCACAAGTGAAAGAGAATCCTTTGATGAT
TAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References