Detailed information of TA system TA073160

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): FicTA/-
• Location: 1062287..1062948
• Replicon: chromosome
• Accession: NZ_CP019684
• Organism: Campylobacter sputorum bv. paraureolyticus LMG 11764 strain LMG 17589

Toxin (Protein)

• Gene name: Fic
• Uniprot ID: -
• Locus tag: CSPARA_RS08805
• Protein ID: WP_153038894.1
• Coordinates: 1062517..1062948 (+)
• Length: 144 a.a.

Antitoxin (Protein)

• Gene name: Fti
• Uniprot ID: -
• Locus tag: CSPARA_RS05285
• Protein ID: WP_089189518.1
• Coordinates: 1062287..1062520 (+)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CSPARA_RS05255	1058251..1059024	-	774	WP_089189516.1	5-oxoprolinase subunit PxpA	-
CSPARA_RS05260	1059335..1060030	+	696	WP_089182651.1	ABC transporter permease	-
CSPARA_RS05265	1060174..1060863	+	690	WP_089182652.1	TVP38/TMEM64 family protein	-
CSPARA_RS05270	1060829..1061458	+	630	WP_089182653.1	TVP38/TMEM64 family protein	-
CSPARA_RS05275	1061703..1061933	+	231	WP_089189517.1	hypothetical protein	-
CSPARA_RS05280	1061917..1062148	+	232	Protein_1035	cell filamentation protein Fic	-
CSPARA_RS05285	1062287..1062520	+	234	WP_089189518.1	hypothetical protein	Antitoxin
CSPARA_RS08805	1062517..1062948	+	432	WP_153038894.1	hypothetical protein	Toxin
CSPARA_RS08810	1062938..1063190	+	253	Protein_1038	Fic family protein	-
CSPARA_RS05295	1063582..1063968	+	387	WP_089182655.1	rhodanese-like domain-containing protein	-
CSPARA_RS05300	1063965..1065413	+	1449	WP_089189519.1	TIGR04282 family arsenosugar biosynthesis glycosyltransferase	-
CSPARA_RS05305	1065398..1066054	+	657	WP_089189520.1	TIGR04283 family arsenosugar biosynthesis glycosyltransferase	-
CSPARA_RS05310	1066041..1067012	+	972	WP_089182658.1	(Fe-S)-binding protein	-
CSPARA_RS05315	1067063..1067923	+	861	WP_089189983.1	arsenosugar biosynthesis radical SAM protein ArsS	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-122)

Antitoxin

• Ribbon-helix-helix protein, CopG (2-38)

Sequences

Toxin

Protein

• Length: 144 a.a.
• Molecular weight: 16833.44 Da
• Isoelectric Point: 9.6264

>T73160 WP_153038894.1 NZ_CP019684:1062517-1062948 [Campylobacter sputorum bv. paraureolyticus LMG 11764]
VIDKILNFMNNCIPKNDFDRQLLASNLVGAKNLKELNRLERIITIQKINDLDINPIKGNFDYQHLKNIHKFIFEYVYVFA
GFDRADIGLQGAFLKGNQHFVPGNEIKKYSKIIFDELKEQNYLKNSKDLNQFAKKYCKFYYGT

Nucleotide

• Length: 432 bp

>T73160 NZ_CP019684:1062517-1062948 [Campylobacter sputorum bv. paraureolyticus LMG 11764]
GTGATAGATAAAATATTGAATTTTATGAATAATTGCATTCCTAAAAATGACTTTGATAGACAACTTTTAGCTTCAAATTT
AGTTGGTGCAAAAAATTTAAAAGAATTAAATAGACTTGAGCGGATTATTACCATACAAAAAATCAACGATTTGGATATTA
ATCCTATAAAAGGAAATTTTGACTATCAACACTTAAAAAATATTCATAAGTTCATTTTTGAATATGTATATGTCTTTGCT
GGATTTGATAGAGCAGATATTGGATTACAAGGTGCATTTTTAAAAGGAAATCAACATTTTGTTCCTGGTAACGAAATTAA
AAAATACTCTAAGATAATTTTTGATGAATTAAAAGAACAAAATTATTTAAAAAACTCTAAAGATTTAAATCAATTTGCAA
AAAAATACTGCAAATTTTATTATGGAACTTAA

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 9162.46 Da
• Isoelectric Point: 5.6880

>AT73160 WP_089189518.1 NZ_CP019684:1062287-1062520 [Campylobacter sputorum bv. paraureolyticus LMG 11764]
MTYPEVHSLKESLAILDKYKNELNKEQYNSINSTIHNFAIESMYANERDILNMIRVQKREITADEIIVQYKKEWGVL

Nucleotide

• Length: 234 bp

>AT73160 NZ_CP019684:1062287-1062520 [Campylobacter sputorum bv. paraureolyticus LMG 11764]
ATGACATATCCAGAAGTACATAGTTTAAAAGAGAGCTTAGCAATACTTGATAAATATAAAAATGAGCTTAATAAAGAGCA
ATACAATAGCATAAACTCTACAATACACAACTTTGCTATTGAAAGTATGTATGCCAATGAAAGAGATATTTTAAATATGA
TCAGAGTTCAAAAAAGAGAGATAACAGCGGATGAAATTATAGTCCAGTATAAAAAAGAATGGGGCGTATTGTGA