Detailed information of TA system TA073111

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-yefM/YoeB-RelB
• Location: 2719643..2720158
• Replicon: chromosome
• Accession: NZ_CP019640
• Organism: Planococcus sp. Y42

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: B0X71_RS13895
• Protein ID: WP_077589988.1
• Coordinates: 2719643..2719900 (-)
• Length: 86 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: B0X71_RS13900
• Protein ID: WP_077589989.1
• Coordinates: 2719901..2720158 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B0X71_RS13880	2716734..2716982	-	249	WP_077589985.1	hypothetical protein	-
B0X71_RS13885	2716984..2717586	-	603	WP_077589986.1	hypothetical protein	-
B0X71_RS13890	2718394..2719347	+	954	WP_077589987.1	alpha/beta hydrolase	-
B0X71_RS13895	2719643..2719900	-	258	WP_077589988.1	Txe/YoeB family addiction module toxin	Toxin
B0X71_RS13900	2719901..2720158	-	258	WP_077589989.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
B0X71_RS13905	2720339..2721694	+	1356	WP_077589990.1	hypothetical protein	-
B0X71_RS13910	2721837..2722262	-	426	WP_077589991.1	CBS domain-containing protein	-
B0X71_RS13915	2722597..2723667	+	1071	WP_077589992.1	aldo/keto reductase	-
B0X71_RS13920	2723838..2724437	+	600	WP_077589993.1	DsbA family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (2-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 86 a.a.
• Molecular weight: 10341.78 Da
• Isoelectric Point: 8.7881

>T73111 WP_077589988.1 NZ_CP019640:c2719900-2719643 [Planococcus sp. Y42]
VNLVFTEQAWAEYVSWQTEDKKTLKRINLLIQDIQRNGYEGIGKPEPLRFDLAGYWSRRINETDRLVYRIDEKNVYILQC
KYHYK

Nucleotide

• Length: 258 bp

>T73111 NZ_CP019640:c2719900-2719643 [Planococcus sp. Y42]
GTGAATCTTGTCTTTACAGAACAGGCTTGGGCAGAATATGTTTCTTGGCAGACAGAGGACAAAAAAACGTTGAAACGGAT
TAACCTGCTTATCCAAGATATTCAGCGCAATGGATATGAAGGTATCGGTAAGCCTGAACCGCTTCGCTTTGATTTGGCGG
GATATTGGTCAAGAAGAATTAACGAAACCGATCGCTTAGTTTATCGGATTGATGAAAAAAACGTCTATATTCTGCAGTGT
AAATATCACTATAAATAA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9938.11 Da
• Isoelectric Point: 4.5482

>AT73111 WP_077589989.1 NZ_CP019640:c2720158-2719901 [Planococcus sp. Y42]
MEAVNYSTFRTNLKDYLDRVTDDYETLIVTRKNEKNVVIISADEYDNLMENVHLLGNEANRRRLMESKKQLEEGLAASRN
LLETD

Nucleotide

• Length: 258 bp

>AT73111 NZ_CP019640:c2720158-2719901 [Planococcus sp. Y42]
ATGGAAGCAGTCAATTACTCCACTTTCCGAACAAATTTAAAAGATTATTTAGATCGGGTGACAGATGACTATGAGACATT
AATCGTTACACGTAAAAATGAAAAGAATGTTGTCATAATCTCTGCAGATGAATACGATAATTTAATGGAAAATGTCCATT
TGCTTGGTAACGAAGCGAACCGTCGACGCTTGATGGAGTCCAAAAAGCAGTTGGAAGAAGGCTTGGCTGCATCACGCAAC
CTACTGGAGACGGATTAA