Detailed information of TA system TA073110

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 1720533..1721015
• Replicon: chromosome
• Accession: NZ_CP019640
• Organism: Planococcus sp. Y42

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: B0X71_RS08795
• Protein ID: WP_077589060.1
• Coordinates: 1720533..1720796 (-)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: B0X71_RS08800
• Protein ID: WP_077589061.1
• Coordinates: 1720803..1721015 (-)
• Length: 71 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B0X71_RS20880	1716701..1716796	+	96	WP_156889942.1	hypothetical protein	-
B0X71_RS08775	1718534..1718944	-	411	WP_077589057.1	heme-binding protein	-
B0X71_RS08780	1719270..1719518	+	249	WP_156889824.1	hypothetical protein	-
B0X71_RS08785	1719604..1719855	+	252	WP_077589059.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	-
B0X71_RS21220	1720034..1720314	-	281	Protein_1658	AbrB family transcriptional regulator	-
B0X71_RS08795	1720533..1720796	-	264	WP_077589060.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
B0X71_RS08800	1720803..1721015	-	213	WP_077589061.1	hypothetical protein	Antitoxin
B0X71_RS08805	1721281..1722456	+	1176	WP_077589062.1	IS256 family transposase	-
B0X71_RS08810	1723067..1724767	+	1701	WP_077589063.1	acetate--CoA ligase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	IScluster/Tn	-	-	1717050..1722456	5406

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-86)

Antitoxin

• Protein of unknown function DUF6290 (1-68)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10191.92 Da
• Isoelectric Point: 10.0689

>T73110 WP_077589060.1 NZ_CP019640:c1720796-1720533 [Planococcus sp. Y42]
MYAVRFSDVALKKLKKMDRYQASLLIGWIEKNLQDSSDPRTLGKALVANHKGKWRYRVGDYRILALIEDEKILITIIDVG
HRKDIYE

Nucleotide

• Length: 264 bp

>T73110 NZ_CP019640:c1720796-1720533 [Planococcus sp. Y42]
ATGTATGCTGTTCGTTTTTCAGATGTCGCCTTGAAGAAATTAAAAAAGATGGATCGTTACCAAGCTTCGCTCCTGATTGG
CTGGATTGAAAAAAACTTGCAGGATTCCAGCGATCCCCGAACACTTGGAAAGGCATTGGTTGCGAACCACAAGGGAAAGT
GGCGTTACCGCGTCGGTGATTACCGTATCCTGGCTTTAATCGAAGATGAAAAAATCCTTATTACCATAATCGATGTCGGG
CATCGAAAAGATATCTACGAATAA

Antitoxin

Protein

• Length: 71 a.a.
• Molecular weight: 8130.27 Da
• Isoelectric Point: 4.6579

>AT73110 WP_077589061.1 NZ_CP019640:c1721015-1720803 [Planococcus sp. Y42]
MATISLRVDDRDSKLIRDYAKMKKTSVSDLMRNATIEKIEDEIDVENFDRVLASMEKTHSLDDVKKELDL

Nucleotide

• Length: 213 bp

>AT73110 NZ_CP019640:c1721015-1720803 [Planococcus sp. Y42]
ATGGCCACCATTTCCTTGCGTGTGGACGACCGCGACAGCAAACTCATACGCGATTACGCCAAAATGAAGAAGACGTCCGT
TTCCGATTTGATGCGAAACGCCACCATTGAAAAAATCGAAGATGAGATTGATGTGGAGAATTTTGACCGTGTGCTTGCCA
GTATGGAAAAAACCCATTCCTTGGATGACGTCAAGAAAGAATTGGATCTATAA