Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazF-pemI/MazF(toxin)
Location 503427..504099 Replicon chromosome
Accession NZ_CP019640
Organism Planococcus sp. Y42

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag B0X71_RS02710 Protein ID WP_077588013.1
Coordinates 503749..504099 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag B0X71_RS02705 Protein ID WP_077588012.1
Coordinates 503427..503744 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B0X71_RS02680 499204..499683 + 480 WP_077588008.1 PH domain-containing protein -
B0X71_RS02685 499676..501165 + 1490 Protein_501 PH domain-containing protein -
B0X71_RS02690 501202..501825 - 624 WP_077588009.1 rhomboid family intramembrane serine protease -
B0X71_RS02695 501896..502261 + 366 WP_077588010.1 holo-ACP synthase -
B0X71_RS02700 502263..503354 + 1092 WP_077588011.1 alanine racemase -
B0X71_RS02705 503427..503744 + 318 WP_077588012.1 transcriptional regulator Antitoxin
B0X71_RS02710 503749..504099 + 351 WP_077588013.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
B0X71_RS02715 504283..505110 + 828 WP_077588014.1 STAS domain-containing protein -
B0X71_RS02720 505107..505469 + 363 WP_077588015.1 STAS domain-containing protein -
B0X71_RS02725 505473..505874 + 402 WP_077588016.1 anti-sigma regulatory factor -
B0X71_RS02730 505887..506888 + 1002 WP_077588017.1 PP2C family protein-serine/threonine phosphatase -
B0X71_RS02735 507024..507353 + 330 WP_077588018.1 STAS domain-containing protein -
B0X71_RS02740 507356..507826 + 471 WP_077588019.1 anti-sigma B factor RsbW -
B0X71_RS02745 507804..508586 + 783 WP_077588020.1 RNA polymerase sigma factor SigB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(4-110)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12670.65 Da        Isoelectric Point: 5.7300

>T73109 WP_077588013.1 NZ_CP019640:503749-504099 [Planococcus sp. Y42]
MIVKRGDVFFAELSPVVGSEQGGTRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEISAKANGFERDSVVLLEQI
RTIDKSRLTDKITHLDDGLMEKVDEALEVSVGLVKF

Download         Length: 351 bp

>T73109 NZ_CP019640:503749-504099 [Planococcus sp. Y42]
TTGATTGTAAAACGCGGAGACGTTTTTTTTGCAGAGTTATCACCAGTAGTCGGTTCCGAGCAGGGCGGGACCCGGCCTGT
TCTGGTTATTCAAAACGATATTGGAAACCGCTTCAGCCCGACAGTCATTGTAGCGGCGATCACAGCACAGATTCAGAAAG
CGAAATTGCCGACTCATGTTGAAATCAGCGCGAAAGCGAATGGGTTTGAACGTGACTCGGTCGTTTTGCTTGAACAGATC
CGGACCATTGACAAGTCACGGCTGACGGATAAAATTACCCATCTTGATGATGGACTCATGGAAAAAGTGGACGAAGCGCT
GGAAGTCAGCGTTGGACTTGTGAAATTTTAG

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11783.30 Da        Isoelectric Point: 5.5974

>AT73109 WP_077588012.1 NZ_CP019640:503427-503744 [Planococcus sp. Y42]
MGFREVSAVYENESAKTKEVIVKLPKTMVSELTACTYEHVEEAGDYVYVSTQRVKRTTYGSNHIREAMIKGYVEMSQINL
SIACECSHAEYEAEHNLSVRLVSGG

Download         Length: 318 bp

>AT73109 NZ_CP019640:503427-503744 [Planococcus sp. Y42]
ATGGGGTTCCGGGAGGTGTCAGCTGTGTACGAGAACGAAAGTGCGAAGACAAAAGAAGTGATTGTGAAGCTGCCAAAAAC
CATGGTGTCAGAACTGACAGCATGCACATATGAACATGTGGAAGAAGCTGGCGACTACGTTTACGTGTCGACACAACGGG
TAAAGAGAACTACTTATGGTTCAAATCACATTCGGGAAGCGATGATCAAGGGCTACGTGGAGATGTCACAGATCAATCTT
TCGATTGCCTGTGAGTGTTCTCACGCGGAATACGAAGCGGAGCATAACCTGTCAGTGCGACTCGTAAGCGGAGGGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References