Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2834413..2835809 Replicon chromosome
Accession NZ_CP019633
Organism Sedimentisphaera cyanobacteriorum strain L21-RPul-D3

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag L21SP3_RS11255 Protein ID WP_161488195.1
Coordinates 2834413..2835138 (-) Length 242 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag L21SP3_RS11260 Protein ID WP_077541575.1
Coordinates 2835201..2835809 (-) Length 203 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L21SP3_RS11240 2830067..2832253 + 2187 WP_077541567.1 amino acid adenylation domain-containing protein -
L21SP3_RS11245 2832250..2832672 + 423 WP_077541569.1 hypothetical protein -
L21SP3_RS11920 2832653..2832871 + 219 WP_123785191.1 hypothetical protein -
L21SP3_RS11250 2832934..2833743 - 810 WP_077541571.1 KilA-N domain-containing protein -
L21SP3_RS11925 2833934..2834194 - 261 WP_123785192.1 hypothetical protein -
L21SP3_RS12040 2834191..2834337 - 147 WP_161488194.1 hypothetical protein -
L21SP3_RS11255 2834413..2835138 - 726 WP_161488195.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
L21SP3_RS11260 2835201..2835809 - 609 WP_077541575.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
L21SP3_RS11265 2835865..2836509 - 645 WP_077541577.1 hypothetical protein -
L21SP3_RS11275 2837706..2838632 - 927 WP_077541581.1 RluA family pseudouridine synthase -
L21SP3_RS11280 2838685..2838900 - 216 WP_077541583.1 hypothetical protein -
L21SP3_RS11285 2839089..2839634 - 546 WP_077541584.1 chromate transporter -
L21SP3_RS11290 2839631..2840164 - 534 WP_118084584.1 chromate transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(17-239)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(8-53)


Sequences

Toxin        


Download         Length: 242 a.a.        Molecular weight: 27925.65 Da        Isoelectric Point: 5.2397

>T73108 WP_161488195.1 NZ_CP019633:c2835138-2834413 [Sedimentisphaera cyanobacteriorum]
MQREDRGLTLTNYAIERFLYRLSNSQYANDFVLKGAQLFRVWGNNPYRPTRDLDLLGFGNPDVSRLEEVFRNICRIETDV
QDGITYKAESVRGQAIREDNMYDGVRIKLEYRIGRTGEFMQIDIGFGDEVYPPEKQAAFPAILNMPAPKLRTYSYELAVA
EKIEAMVTLGFANSRMKDFYDVYQLAGKFEFDGKLLAQAIQNTFRRRGTAIPEELPTSFTREFYEDKLKQSQWDALSQKI
A

Download         Length: 726 bp

>T73108 NZ_CP019633:c2835138-2834413 [Sedimentisphaera cyanobacteriorum]
ATGCAAAGGGAAGATCGCGGCCTTACGCTGACAAATTATGCAATAGAGCGTTTTCTTTATCGATTGAGCAATTCTCAATA
TGCCAACGATTTTGTTCTCAAGGGAGCGCAGCTTTTTCGGGTATGGGGGAATAATCCTTACCGGCCAACGAGAGATCTTG
ATTTGCTTGGGTTTGGCAATCCTGATGTTTCCCGGCTGGAGGAGGTTTTCAGAAATATTTGCCGGATCGAAACTGATGTG
CAGGACGGAATCACATATAAAGCGGAATCTGTGAGAGGGCAGGCAATTCGGGAAGATAATATGTATGACGGCGTAAGGAT
TAAGCTTGAATACAGAATAGGGCGTACGGGAGAATTTATGCAGATAGACATTGGGTTTGGTGATGAGGTTTATCCGCCTG
AAAAGCAGGCCGCTTTCCCTGCAATACTTAATATGCCGGCACCAAAGCTAAGGACATACTCGTATGAGCTGGCAGTAGCT
GAAAAGATTGAAGCAATGGTAACTCTGGGGTTTGCGAACAGCCGTATGAAAGATTTTTACGATGTGTATCAGCTTGCCGG
AAAATTTGAATTCGACGGCAAACTGTTAGCTCAGGCGATTCAAAACACATTTAGGCGAAGAGGTACAGCAATCCCCGAAG
AACTGCCTACATCTTTTACCAGAGAATTCTATGAAGACAAATTGAAACAGAGCCAGTGGGATGCTTTATCTCAAAAAATA
GCCTAA

Antitoxin


Download         Length: 203 a.a.        Molecular weight: 23254.11 Da        Isoelectric Point: 10.2898

>AT73108 WP_077541575.1 NZ_CP019633:c2835809-2835201 [Sedimentisphaera cyanobacteriorum]
MGIKAQKLIEHLRQYGMLKTGEIVELGISKEYLRKLTVQGTVERVSRGLYSLPNNDYSPMQSIAEASKQVPKGVICLLSA
LRLHGFTTQNPFEVWIAIENRSRKPEIKASAKVRYVRFSKRAFTEGIQEKRIDQLKVRVYSPAKTVADCFKYRNKIGLDT
ALEALREGWREKHFTMDELWKYAKVCRVSNVIQPYLESITAL

Download         Length: 609 bp

>AT73108 NZ_CP019633:c2835809-2835201 [Sedimentisphaera cyanobacteriorum]
ATGGGAATAAAGGCTCAAAAACTAATTGAACATCTCAGACAGTATGGAATGCTCAAAACAGGAGAAATCGTTGAGCTTGG
CATCTCGAAGGAGTATCTTCGAAAGCTTACGGTACAAGGAACTGTGGAGAGGGTTTCCCGCGGCCTCTACAGTCTGCCCA
ACAATGATTACTCGCCGATGCAGAGCATTGCTGAGGCTTCGAAACAGGTGCCTAAAGGGGTAATTTGCCTTCTTTCTGCC
CTGCGTCTTCACGGATTTACAACACAGAATCCATTTGAGGTCTGGATTGCGATAGAAAATCGTTCCCGCAAACCCGAAAT
TAAAGCTTCTGCAAAGGTGAGATATGTGCGGTTTTCGAAAAGGGCATTTACCGAAGGAATACAGGAGAAACGGATAGATC
AGCTTAAGGTGCGAGTTTATTCGCCGGCAAAGACGGTGGCGGATTGTTTTAAATATCGCAACAAGATTGGGCTGGATACA
GCTCTGGAAGCCCTTAGAGAAGGCTGGCGGGAAAAGCATTTTACAATGGATGAGCTTTGGAAATACGCCAAAGTGTGCAG
GGTGAGCAATGTGATTCAGCCATATCTTGAAAGCATTACTGCATTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References