Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 2569545..2571049 Replicon chromosome
Accession NZ_CP019633
Organism Sedimentisphaera cyanobacteriorum strain L21-RPul-D3

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag L21SP3_RS10345 Protein ID WP_161488179.1
Coordinates 2570144..2571049 (+) Length 302 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag L21SP3_RS10340 Protein ID WP_077541240.1
Coordinates 2569545..2570147 (+) Length 201 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L21SP3_RS10320 2564712..2565752 + 1041 WP_123785186.1 thiamine phosphate synthase -
L21SP3_RS10325 2565881..2567170 + 1290 WP_077541234.1 hemolysin family protein -
L21SP3_RS10330 2567176..2567928 + 753 WP_077541236.1 DNA repair protein RecO -
L21SP3_RS10335 2568074..2569273 - 1200 WP_077541238.1 DNA-binding transcriptional regulator -
L21SP3_RS10340 2569545..2570147 + 603 WP_077541240.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
L21SP3_RS10345 2570144..2571049 + 906 WP_161488179.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
L21SP3_RS10350 2571040..2571627 + 588 WP_077541244.1 hypothetical protein -
L21SP3_RS10355 2571630..2572142 + 513 WP_077541246.1 hypothetical protein -
L21SP3_RS10360 2572520..2573770 + 1251 Protein_2001 IS5 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(35-271)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(6-50)


Sequences

Toxin        


Download         Length: 302 a.a.        Molecular weight: 35019.31 Da        Isoelectric Point: 8.9912

>T73107 WP_161488179.1 NZ_CP019633:2570144-2571049 [Sedimentisphaera cyanobacteriorum]
VTSRKAQSIRQQLLNITNERSVDYNLTLIWYALERLLYRLSRSKYSSRFILKGAMLFTVWSGRSFRPTKDIDFLGFGKSS
AQDLKNLFTEIIQINDDLNDGLVFLSESLSVQPIREEQEYGGQRITLNALLGNARIRLQIDIGFGDAITPVPEKIQFPTL
LEMPAPEILIYNRETVIAEKFHAINVLGLASSRMKDYYDLWILSKQYEFDGNLLAKAIQTTFERRKTSLPEKMPLGLTDE
FYKDEIILTRWNAFVRKTELGIVEKRLEAVVERLQLFFDDVIRALATSENFDKKWDKNQWK

Download         Length: 906 bp

>T73107 NZ_CP019633:2570144-2571049 [Sedimentisphaera cyanobacteriorum]
GTGACATCCAGAAAAGCTCAGTCCATTCGACAACAACTTCTTAATATCACCAATGAAAGATCTGTCGATTATAACCTCAC
TCTAATCTGGTATGCCCTGGAACGGCTGCTCTATAGACTTAGCAGGTCTAAGTATTCAAGTCGTTTCATTCTTAAGGGTG
CTATGCTTTTTACTGTTTGGTCAGGGAGATCATTCAGACCAACAAAAGATATTGATTTTTTAGGTTTTGGCAAATCTTCA
GCGCAAGATCTCAAGAATCTATTTACTGAGATTATTCAAATAAATGACGACTTGAATGACGGCCTTGTGTTTTTAAGTGA
AAGCCTTAGTGTACAGCCTATTCGTGAAGAGCAGGAATACGGAGGACAGCGAATTACCCTGAATGCCTTGCTTGGAAATG
CCCGTATTCGTTTGCAAATTGATATTGGCTTCGGAGATGCCATAACGCCTGTACCGGAAAAGATTCAGTTTCCCACTCTG
TTAGAGATGCCTGCACCAGAAATTCTAATTTATAATAGAGAGACGGTAATTGCAGAAAAATTTCATGCCATAAATGTACT
GGGGCTTGCAAGTAGCAGAATGAAAGACTACTACGATCTGTGGATACTATCGAAGCAATATGAGTTCGACGGAAATCTTC
TGGCAAAAGCTATCCAGACAACTTTTGAGAGGCGAAAGACATCGTTGCCAGAAAAAATGCCGCTTGGGCTAACAGATGAA
TTTTACAAGGATGAAATTATTCTTACACGATGGAATGCTTTTGTTAGAAAAACAGAATTGGGCATAGTCGAGAAAAGATT
GGAAGCAGTCGTTGAAAGATTACAGCTATTTTTCGATGATGTAATCAGGGCGTTAGCGACAAGCGAAAATTTTGACAAAA
AATGGGACAAAAATCAATGGAAATAA

Antitoxin


Download         Length: 201 a.a.        Molecular weight: 23041.71 Da        Isoelectric Point: 10.4577

>AT73107 WP_077541240.1 NZ_CP019633:2569545-2570147 [Sedimentisphaera cyanobacteriorum]
MNDKEKILKYAAKKGAISPREIESVGISRQKLYRLYREGKLVRVDRGTYSIRNVEPTEWHTYVTVAVAFPKSVICLLSAL
QFHNLTTQNPHNVWIALDREADRRNPKRSRQPVSIVRFSGDSFSQGIETHSIEGVHVQIYSAAKTVADCFKYRNKIGLEI
AIEAMTDCIRKKKATRDRIWQFAKICRVSKVIRPYMEAIT

Download         Length: 603 bp

>AT73107 NZ_CP019633:2569545-2570147 [Sedimentisphaera cyanobacteriorum]
ATGAACGACAAAGAAAAAATACTGAAATATGCTGCTAAAAAAGGGGCAATCAGTCCCAGAGAAATCGAGAGTGTGGGTAT
TTCACGGCAAAAGCTCTATAGACTTTATCGTGAAGGCAAACTGGTTCGAGTAGACCGTGGTACATATTCTATTCGGAATG
TTGAGCCGACCGAATGGCATACTTACGTTACTGTAGCAGTGGCTTTCCCTAAATCTGTAATATGTCTGCTTTCCGCACTT
CAATTTCATAACCTTACAACACAGAATCCCCATAACGTTTGGATTGCTCTTGACCGAGAAGCGGACAGAAGGAATCCGAA
ACGCAGTCGCCAGCCGGTTTCGATTGTTCGATTTTCAGGAGATTCTTTTTCACAGGGTATTGAAACTCACAGTATCGAAG
GGGTTCACGTTCAAATATACAGTGCAGCGAAAACCGTGGCAGACTGCTTTAAGTATCGCAACAAGATAGGGCTGGAAATA
GCAATAGAAGCAATGACTGATTGTATTCGTAAGAAAAAAGCTACGCGAGATCGAATCTGGCAGTTCGCCAAAATATGCAG
AGTATCAAAAGTCATCAGACCTTACATGGAGGCAATAACGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References