Detailed information of TA system TA073106

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/LOTUS_5_Limkain_b1-Phd
• Location: 47098..47744
• Replicon: plasmid unnamed2
• Accession: NZ_CP019632
• Organism: Labrenzia aggregata strain RMAR6-6

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: B0E33_RS30465
• Protein ID: WP_062492135.1
• Coordinates: 47098..47505 (-)
• Length: 136 a.a.

Antitoxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: B0E33_RS30470
• Protein ID: WP_077294775.1
• Coordinates: 47502..47744 (-)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
B0E33_RS30445	43672..43959	-	288	WP_077294769.1	hypothetical protein	-
B0E33_RS30450	44264..44608	-	345	WP_077294866.1	DUF736 family protein	-
B0E33_RS30455	44884..46602	-	1719	WP_077294772.1	Fic family protein	-
B0E33_RS30460	46667..46873	-	207	WP_062492137.1	antitoxin VbhA family protein	-
B0E33_RS30465	47098..47505	-	408	WP_062492135.1	type II toxin-antitoxin system VapC family toxin	Toxin
B0E33_RS30470	47502..47744	-	243	WP_077294775.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
B0E33_RS30475	47859..49115	-	1257	WP_077294778.1	replication protein C	-
B0E33_RS30480	49339..50340	-	1002	WP_077294781.1	plasmid partitioning protein RepB	-
B0E33_RS30485	50344..51537	-	1194	WP_077294784.1	plasmid partitioning protein RepA	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..94445	94445

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (3-118)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (2-50)

Sequences

Toxin

Protein

• Length: 136 a.a.
• Molecular weight: 15120.26 Da
• Isoelectric Point: 5.2058

>T73106 WP_062492135.1 NZ_CP019632:c47505-47098 [Labrenzia aggregata]
MIYVLDTNVITAARRAERAPKVAAWLSDKPEETLYVSVVTLGEIERGIRLQERRNMDFAKHLRQWLDRTVSMFGDRLLEF
TASDALCWGELSARIGHNGADLMIAAQALTRNGWVVTGNASDFEPTGVQLVDPFV

Nucleotide

• Length: 408 bp

>T73106 NZ_CP019632:c47505-47098 [Labrenzia aggregata]
TTGATCTATGTTCTGGATACAAACGTGATTACTGCCGCAAGGCGTGCGGAAAGAGCGCCCAAGGTCGCTGCCTGGTTGTC
GGATAAGCCGGAGGAAACGCTCTATGTGAGCGTTGTCACGCTTGGCGAAATTGAAAGAGGAATCCGGCTTCAGGAACGGC
GGAATATGGATTTTGCCAAGCATCTTCGTCAGTGGTTGGACCGGACGGTTTCAATGTTTGGAGACCGGTTGTTGGAGTTT
ACCGCATCAGATGCCTTATGTTGGGGTGAGCTCTCCGCGAGAATTGGTCACAACGGCGCTGATCTGATGATTGCTGCTCA
GGCTTTGACCCGTAACGGATGGGTCGTTACCGGGAACGCGTCTGATTTTGAACCGACAGGCGTGCAACTTGTCGATCCAT
TCGTTTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 8988.22 Da
• Isoelectric Point: 10.4416

>AT73106 WP_077294775.1 NZ_CP019632:c47744-47502 [Labrenzia aggregata]
MISLQDAKNRFSAVVEAAMAGRPQEVSRRGKPAVVVISSEEYRRLLREAKGRRESFADHVLSFPGEGIERSKVSPRDVEF

Nucleotide

• Length: 243 bp

>AT73106 NZ_CP019632:c47744-47502 [Labrenzia aggregata]
ATGATTTCTCTTCAAGATGCAAAGAACAGATTCAGCGCTGTGGTTGAAGCCGCAATGGCTGGCCGGCCTCAGGAAGTGTC
CCGCAGAGGCAAACCAGCTGTCGTCGTTATTTCCTCGGAAGAGTATCGCCGGCTTCTCAGAGAAGCGAAGGGGCGGCGCG
AGAGCTTTGCAGACCATGTCCTCAGCTTCCCGGGAGAGGGCATTGAGCGATCAAAGGTATCGCCCCGGGATGTCGAATTT
TGA