Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 413828..415067 Replicon chromosome
Accession NZ_CP019630
Organism Labrenzia aggregata strain RMAR6-6

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag B0E33_RS02050 Protein ID WP_077293108.1
Coordinates 414447..415067 (+) Length 207 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag B0E33_RS02045 Protein ID WP_077290288.1
Coordinates 413828..414397 (+) Length 190 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
B0E33_RS02025 409876..410724 - 849 WP_023000192.1 phosphonate ABC transporter, permease protein PhnE -
B0E33_RS02030 410907..411821 - 915 WP_077290287.1 phosphonate ABC transporter substrate-binding protein -
B0E33_RS02035 411880..412713 - 834 WP_077293107.1 phosphonate ABC transporter ATP-binding protein -
B0E33_RS02040 413113..413739 + 627 WP_055659209.1 chloramphenicol acetyltransferase -
B0E33_RS02045 413828..414397 + 570 WP_077290288.1 helix-turn-helix transcriptional regulator Antitoxin
B0E33_RS02050 414447..415067 + 621 WP_077293108.1 HD domain-containing protein Toxin
B0E33_RS02055 415207..415578 + 372 WP_077290289.1 STAS/SEC14 domain-containing protein -
B0E33_RS02060 415663..416451 - 789 WP_023000199.1 class II glutamine amidotransferase -
B0E33_RS02065 416468..417934 - 1467 WP_077290290.1 aminotransferase class V-fold PLP-dependent enzyme -
B0E33_RS02070 418039..418500 + 462 WP_023000201.1 Lrp/AsnC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 278113..442920 164807


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HD domain

(28-168)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-68)


Sequences

Toxin        


Download         Length: 207 a.a.        Molecular weight: 23074.28 Da        Isoelectric Point: 4.6200

>T73103 WP_077293108.1 NZ_CP019630:414447-415067 [Labrenzia aggregata]
MTKTPPSLDLPEIPHTRLTGLLDFLQAAEQLKDTLRSGTTTGGRPESTAEHSWRLALMVLLFEPELKEVDLLKLLKLTLV
HDLGEAISGDVPAPLQTPGDDRQERERRDFLTLCEPLPGDVAGELTSLWDEYAAARTVEARLAKAFDKLETMLQHVLMPR
QAPSFYEFNLGYGRDRTDCSALTRQLRDEVDELTRTMMTGAGREIA

Download         Length: 621 bp

>T73103 NZ_CP019630:414447-415067 [Labrenzia aggregata]
ATGACAAAGACGCCCCCTTCCCTCGATCTTCCTGAAATTCCCCACACCAGACTGACGGGCCTGCTGGACTTCCTTCAGGC
TGCAGAGCAGCTGAAAGACACGCTTCGCTCGGGAACGACAACCGGCGGCAGGCCGGAGAGCACTGCCGAACATAGCTGGC
GACTGGCCTTGATGGTTCTGTTGTTCGAACCAGAGCTGAAAGAAGTCGACTTGCTCAAACTCCTGAAGCTGACGCTTGTG
CATGACCTGGGCGAAGCCATCTCCGGAGATGTCCCCGCTCCACTCCAGACGCCGGGTGACGACCGGCAGGAACGCGAGAG
GCGGGACTTCCTGACCTTGTGTGAACCGCTGCCGGGTGACGTGGCTGGGGAGCTAACCTCTCTCTGGGATGAGTATGCAG
CGGCACGAACCGTCGAAGCCCGACTTGCCAAGGCGTTCGACAAGCTGGAGACCATGCTTCAGCACGTTCTGATGCCAAGG
CAAGCGCCTTCATTTTATGAGTTCAACCTGGGTTACGGCCGTGATCGTACCGATTGCAGTGCTCTCACGCGCCAGTTGCG
GGACGAAGTCGACGAGCTGACCCGCACCATGATGACGGGCGCCGGACGGGAAATCGCCTGA

Antitoxin


Download         Length: 190 a.a.        Molecular weight: 21683.64 Da        Isoelectric Point: 6.9737

>AT73103 WP_077290288.1 NZ_CP019630:413828-414397 [Labrenzia aggregata]
MQTETAVLESSLGPSLRRWRVLNRVKQEALAHELGVSQTRISRWESGMSQPDDSDRAKITRLLRARPESAADKALLDLVS
RSAVPVHLVCDLTHRLLAMSVPRACEWRAPVNEFLNRPLWRFASEGIRATEHRLTDYGWFEPDSPDIVYRTEHVDFPEMT
IPESIIRISRLPLSDGRFARLVREEQDSA

Download         Length: 570 bp

>AT73103 NZ_CP019630:413828-414397 [Labrenzia aggregata]
ATGCAAACAGAAACCGCCGTTCTTGAAAGCAGTCTTGGACCGTCGCTGCGGCGCTGGCGCGTACTGAACCGGGTCAAGCA
AGAAGCTCTGGCGCATGAACTCGGCGTCTCGCAGACGAGGATATCGCGCTGGGAGAGTGGCATGTCGCAGCCGGACGACA
GCGACAGGGCGAAGATCACCCGTCTGCTGAGGGCACGTCCGGAGAGCGCCGCCGACAAGGCCCTGCTTGATCTTGTCTCC
CGGTCCGCAGTTCCCGTGCATCTGGTCTGCGACCTCACACACAGGCTGCTGGCCATGTCCGTACCGCGTGCCTGCGAATG
GCGCGCACCGGTGAACGAGTTTCTGAACCGGCCCCTGTGGCGTTTTGCGTCCGAAGGCATCCGGGCAACGGAGCACAGAC
TGACCGACTATGGCTGGTTCGAGCCGGATTCTCCGGACATTGTCTACCGAACAGAACACGTTGATTTTCCGGAAATGACC
ATCCCGGAGAGCATCATCCGGATTTCGCGCCTGCCGCTGTCAGACGGACGGTTTGCGCGGCTGGTCCGTGAAGAACAGGA
TTCCGCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References