Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PhRel-ATphRel/-
Location 5415649..5416684 Replicon chromosome
Accession NZ_CP019572
Organism Rhodococcus sp. MTM3W5.2

Toxin (Protein)


Gene name phRel Uniprot ID -
Locus tag BTZ20_RS24780 Protein ID WP_189636546.1
Coordinates 5415649..5416464 (+) Length 272 a.a.

Antitoxin (Protein)


Gene name ATphRel Uniprot ID -
Locus tag BTZ20_RS24785 Protein ID WP_077043176.1
Coordinates 5416457..5416684 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BTZ20_RS24750 5411280..5412272 - 993 WP_189636700.1 hypothetical protein -
BTZ20_RS24765 5413225..5413953 - 729 WP_077043173.1 dienelactone hydrolase family protein -
BTZ20_RS24770 5414068..5415157 + 1090 Protein_4883 histidinol-phosphate transaminase -
BTZ20_RS27450 5415375..5415587 - 213 WP_077043174.1 hypothetical protein -
BTZ20_RS24780 5415649..5416464 + 816 WP_189636546.1 GTP pyrophosphokinase family protein Toxin
BTZ20_RS24785 5416457..5416684 + 228 WP_077043176.1 hypothetical protein Antitoxin
BTZ20_RS24790 5416774..5417967 - 1194 WP_077043177.1 phage major capsid protein -
BTZ20_RS24795 5418407..5418715 - 309 WP_077043178.1 hypothetical protein -
BTZ20_RS26990 5418855..5419160 - 306 WP_189636547.1 HNH endonuclease -
BTZ20_RS27455 5419192..5419401 - 210 WP_189636548.1 hypothetical protein -
BTZ20_RS27000 5419601..5419840 - 240 Protein_4891 hypothetical protein -
BTZ20_RS27460 5419847..5420017 - 171 WP_189636549.1 hypothetical protein -
BTZ20_RS24815 5420514..5420858 - 345 WP_077043181.1 hypothetical protein -
BTZ20_RS24820 5420876..5421067 - 192 WP_077043182.1 hypothetical protein -
BTZ20_RS24825 5421067..5421525 - 459 WP_077043183.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RelA/SpoT

(70-167)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 272 a.a.        Molecular weight: 30622.25 Da        Isoelectric Point: 4.7071

>T72678 WP_189636546.1 NZ_CP019572:5415649-5416464 [Rhodococcus sp. MTM3W5.2]
VDLTETLPWSRRKLRRLGEALAAGDESPDGCPHYDEVMLWHNDLAAEVAATLAITDWTTIDSDSFDLAARPKTLDTLVQK
LRRRPPRLTLDQVQDIAGVRVDAEFTLDSQLALAHEVVAFFGEDSVVKDIRDNPHSGYRAVHVWLRLPPGRVEIQLRTTT
QSAWANTYERLADRIGRGIRYGEIPDAPGIRGVVEHLHTFSNEIAALEQLEQQLSDLQAELEAVPHGDRDDNHRALVRRV
GEIEDGVRDSRSRYIELLLDLKRTLDDMEDA

Download         Length: 816 bp

>T72678 NZ_CP019572:5415649-5416464 [Rhodococcus sp. MTM3W5.2]
GTGGATCTGACGGAAACCCTGCCGTGGTCGCGCCGGAAGCTGCGACGCCTCGGCGAAGCCCTTGCGGCCGGCGACGAATC
GCCAGATGGTTGCCCTCACTACGACGAGGTCATGCTCTGGCACAACGACCTGGCCGCCGAGGTAGCAGCGACACTCGCGA
TCACCGATTGGACGACGATAGATTCAGATTCATTCGACTTGGCTGCACGGCCGAAAACGCTCGACACCCTGGTCCAGAAG
CTCCGCCGCCGTCCGCCGCGGCTCACCTTAGACCAGGTCCAGGACATCGCAGGGGTGCGAGTGGATGCAGAGTTCACACT
CGATTCTCAGCTCGCACTCGCTCACGAGGTTGTTGCTTTCTTCGGCGAGGACTCCGTTGTCAAGGACATACGGGACAATC
CTCATAGCGGCTACCGGGCGGTGCATGTGTGGCTCCGGCTTCCACCCGGCCGTGTGGAGATCCAGTTACGCACGACTACG
CAGAGCGCATGGGCGAACACTTACGAACGTCTCGCCGACAGGATCGGACGCGGAATCCGCTATGGGGAGATTCCGGACGC
CCCCGGCATCCGCGGAGTCGTCGAACACCTCCACACCTTCTCGAATGAGATTGCAGCCCTGGAGCAGCTGGAGCAGCAAC
TTTCCGACCTCCAAGCCGAGCTAGAGGCCGTCCCACACGGTGACAGAGATGACAATCATCGTGCCCTAGTCCGGCGCGTC
GGTGAGATCGAAGATGGTGTCAGGGATTCAAGAAGCAGGTACATTGAGCTGCTACTTGACCTGAAACGTACTCTTGACGA
TATGGAGGATGCTTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8954.14 Da        Isoelectric Point: 8.5812

>AT72678 WP_077043176.1 NZ_CP019572:5416457-5416684 [Rhodococcus sp. MTM3W5.2]
MLDMPGYVIEFNRRTRDRRVHEFVDHQDAMRYRLRLEAERVDRDVEIAALISKSLETLQRTHSRYFTGKELASAS

Download         Length: 228 bp

>AT72678 NZ_CP019572:5416457-5416684 [Rhodococcus sp. MTM3W5.2]
ATGCTTGACATGCCTGGCTACGTCATTGAGTTCAATCGTCGCACCCGAGATCGCCGAGTCCACGAGTTCGTGGACCACCA
GGACGCGATGCGGTACCGCCTTCGTCTTGAAGCCGAACGAGTCGACCGAGATGTGGAAATCGCCGCACTGATCAGCAAGT
CTTTGGAGACACTGCAGCGAACACACTCGCGCTACTTCACTGGCAAGGAGCTTGCCTCGGCCTCGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References