Detailed information of TA system TA072619

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relB-parE/ParE-RHH
• Location: 2067495..2068051
• Replicon: chromosome
• Accession: NZ_CP019515
• Organism: Xanthomonas oryzae pv. oryzae strain SK2-3

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: BXU03_RS10335
• Protein ID: WP_027703932.1
• Coordinates: 2067761..2068051 (+)
• Length: 97 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A854CIX2
• Locus tag: BXU03_RS10330
• Protein ID: WP_011408759.1
• Coordinates: 2067495..2067773 (+)
• Length: 93 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BXU03_RS10300	2062612..2063217	-	606	Protein_1849	DNA-3-methyladenine glycosylase	-
BXU03_RS10305	2063319..2064284	-	966	WP_109181970.1	IS1595-like element ISXo5 family transposase	-
BXU03_RS10315	2064865..2066049	+	1185	WP_117231633.1	IS256 family transposase	-
BXU03_RS10320	2066810..2067010	+	201	WP_027703931.1	ribbon-helix-helix protein, CopG family	-
BXU03_RS24910	2066913..2067299	+	387	WP_205421001.1	hypothetical protein	-
BXU03_RS24915	2067211..2067414	+	204	WP_198912807.1	hypothetical protein	-
BXU03_RS10330	2067495..2067773	+	279	WP_011408759.1	CopG family ribbon-helix-helix protein	Antitoxin
BXU03_RS10335	2067761..2068051	+	291	WP_027703932.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
BXU03_RS24920	2068312..2068509	+	198	WP_153296741.1	hypothetical protein	-
BXU03_RS10345	2068653..2068832	+	180	WP_015463309.1	hypothetical protein	-
BXU03_RS10365	2069696..2070097	-	402	WP_011259345.1	H-NS histone family protein	-
BXU03_RS10370	2070319..2070495	+	177	Protein_1860	DUF3606 domain-containing protein	-
BXU03_RS24620	2070511..2070717	+	207	Protein_1861	hypothetical protein	-
BXU03_RS10380	2070777..2071093	+	317	Protein_1862	ATP-dependent DNA ligase	-
BXU03_RS10385	2071190..2072281	-	1092	WP_011408756.1	ribonuclease D	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-94)

Antitoxin

• Ribbon-helix-helix protein, CopG (5-42)

Sequences

Toxin

Protein

• Length: 97 a.a.
• Molecular weight: 10915.48 Da
• Isoelectric Point: 9.5554

>T72619 WP_027703932.1 NZ_CP019515:2067761-2068051 [Xanthomonas oryzae pv. oryzae]
MPQVIFAPAAIGDMLRLREFLRPKNPDAARRAGEAIRRGVQALGAHPRMGRLIEDLSEQYREWLIDFGDSGYVARYRFDG
DTVTILAVRHQKEAGY

Nucleotide

• Length: 291 bp

>T72619 NZ_CP019515:2067761-2068051 [Xanthomonas oryzae pv. oryzae]
ATGCCACAAGTAATCTTTGCGCCGGCGGCGATCGGGGACATGCTACGGCTGCGTGAATTCCTGAGGCCGAAGAATCCCGA
TGCCGCGAGGCGGGCCGGCGAAGCGATTAGGCGCGGCGTCCAGGCTCTCGGTGCCCACCCTCGAATGGGGCGGCTCATAG
AAGATCTGTCTGAACAGTATCGGGAGTGGCTTATCGATTTTGGGGATAGCGGCTATGTGGCTCGGTACCGCTTCGATGGG
GATACCGTCACGATTTTGGCCGTGCGACACCAGAAGGAAGCGGGGTACTGA

Antitoxin

Protein

• Length: 93 a.a.
• Molecular weight: 10826.11 Da
• Isoelectric Point: 4.9736

>AT72619 WP_011408759.1 NZ_CP019515:2067495-2067773 [Xanthomonas oryzae pv. oryzae]
MVTATSIKLDDELKGRVQHLAESRRRTPHWIMREAIEQYVEREEKREALNRDTLKAWDEFQATGLHVTAEEVDKWLASWG
TDDELPPPECHK

Nucleotide

• Length: 279 bp

>AT72619 NZ_CP019515:2067495-2067773 [Xanthomonas oryzae pv. oryzae]
ATGGTTACGGCAACTTCCATCAAGCTTGATGATGAATTGAAAGGGCGGGTTCAGCACTTGGCAGAGTCGCGCCGGCGTAC
CCCGCATTGGATCATGCGCGAAGCCATTGAGCAGTACGTCGAGCGCGAGGAAAAGCGCGAGGCGCTGAACCGGGACACGC
TCAAGGCATGGGATGAATTTCAGGCGACTGGCCTGCATGTGACCGCTGAGGAAGTGGACAAGTGGCTCGCGAGCTGGGGA
ACTGACGACGAACTGCCTCCGCCAGAATGCCACAAGTAA

Structures

Antitoxin

• AlphaFold DB: A0A854CIX2