Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-CC2985
Location 3315066..3315603 Replicon chromosome
Accession NZ_CP019511
Organism Sphingomonas sp. LM7

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag BXU08_RS15395 Protein ID WP_077510856.1
Coordinates 3315319..3315603 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag BXU08_RS15390 Protein ID WP_171982539.1
Coordinates 3315066..3315329 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BXU08_RS15355 3310790..3311404 - 615 WP_077510851.1 glutathione S-transferase N-terminal domain-containing protein -
BXU08_RS15360 3311482..3312072 + 591 WP_077510852.1 TetR/AcrR family transcriptional regulator -
BXU08_RS15365 3312078..3312647 + 570 WP_077512470.1 DUF2585 domain-containing protein -
BXU08_RS15370 3312663..3313442 + 780 WP_077510853.1 sterol desaturase family protein -
BXU08_RS15375 3313408..3313797 + 390 WP_077512472.1 DUF2141 domain-containing protein -
BXU08_RS15380 3313825..3314136 + 312 WP_077510854.1 alkylphosphonate utilization protein -
BXU08_RS15385 3314562..3314900 - 339 WP_077510855.1 hypothetical protein -
BXU08_RS15390 3315066..3315329 + 264 WP_171982539.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
BXU08_RS15395 3315319..3315603 + 285 WP_077510856.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BXU08_RS15400 3315881..3317029 + 1149 WP_150125661.1 hypothetical protein -
BXU08_RS15405 3317091..3317368 - 278 Protein_3078 phosphomethylpyrimidine synthase ThiC -
BXU08_RS15410 3317478..3317831 - 354 Protein_3079 hypothetical protein -
BXU08_RS15415 3318023..3318340 - 318 Protein_3080 hypothetical protein -
BXU08_RS15420 3318578..3320473 - 1896 WP_077510857.1 phosphomethylpyrimidine synthase ThiC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

Antitoxin ParD

(4-66)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10815.39 Da        Isoelectric Point: 5.1238

>T72578 WP_077510856.1 NZ_CP019511:3315319-3315603 [Sphingomonas sp. LM7]
MRLELSREAQADLDDIRDYSVAQFGVPRAIAYLDAVEQAFRRVLDFPEIGAVRPELAGVRSLGCQQHRLFYTVDGETIRI
VRILHKAMDVEQWL

Download         Length: 285 bp

>T72578 NZ_CP019511:3315319-3315603 [Sphingomonas sp. LM7]
ATGCGGCTTGAGCTGAGCCGCGAGGCTCAGGCCGATCTCGACGATATTCGCGACTATAGCGTCGCACAGTTCGGCGTCCC
CCGCGCGATCGCGTATCTGGATGCAGTGGAACAGGCATTTCGTCGGGTGCTGGATTTCCCCGAAATCGGCGCAGTGCGGC
CAGAGCTTGCCGGCGTTCGATCGCTTGGCTGCCAGCAGCACCGGCTTTTCTACACCGTCGATGGCGAGACGATCCGTATT
GTGCGCATCCTGCACAAGGCGATGGATGTCGAGCAGTGGCTTTGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9689.80 Da        Isoelectric Point: 5.1634

>AT72578 WP_171982539.1 NZ_CP019511:3315066-3315329 [Sphingomonas sp. LM7]
MAQMNISIPDKLKGWAEQRVAEGRYSSTSDYVRDLVRRDQEHAEKLRALRAAIDNGLASGVSERDPFELLDEMRDGLRAA
ARSADAA

Download         Length: 264 bp

>AT72578 NZ_CP019511:3315066-3315329 [Sphingomonas sp. LM7]
ATGGCGCAGATGAACATCTCGATCCCCGACAAGCTCAAGGGCTGGGCGGAACAGCGCGTCGCCGAGGGGCGCTACAGCAG
CACCAGCGACTATGTGCGTGATCTGGTGCGGCGGGATCAGGAACATGCGGAGAAGCTGCGGGCGCTGCGAGCCGCGATCG
ACAACGGGTTGGCGTCGGGCGTGAGCGAGCGCGATCCGTTCGAGCTTCTGGACGAAATGCGCGACGGTTTGCGCGCGGCG
GCGCGGAGCGCGGATGCGGCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References