Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/StbC(antitoxin)
Location 1277389..1278021 Replicon chromosome
Accession NZ_CP019510
Organism Janthinobacterium sp. LM6

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BZG29_RS05715 Protein ID WP_077399893.1
Coordinates 1277605..1278021 (+) Length 139 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BZG29_RS05710 Protein ID WP_077399890.1
Coordinates 1277389..1277598 (+) Length 70 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BZG29_RS05690 1273172..1274410 - 1239 WP_171984943.1 alpha/beta hydrolase -
BZG29_RS05695 1274733..1275971 + 1239 WP_077399881.1 bifunctional glutamate N-acetyltransferase/amino-acid acetyltransferase ArgJ -
BZG29_RS05700 1275968..1276849 + 882 WP_077399884.1 ATP-binding protein -
BZG29_RS05705 1276846..1277268 + 423 WP_077399887.1 NUDIX domain-containing protein -
BZG29_RS05710 1277389..1277598 + 210 WP_077399890.1 hypothetical protein Antitoxin
BZG29_RS05715 1277605..1278021 + 417 WP_077399893.1 PIN domain-containing protein Toxin
BZG29_RS05720 1278164..1278355 - 192 WP_034748814.1 DNA gyrase inhibitor YacG -
BZG29_RS05725 1278374..1279129 - 756 WP_077399896.1 cell division protein ZapD -
BZG29_RS05730 1279192..1279839 - 648 WP_077399899.1 dephospho-CoA kinase -
BZG29_RS05735 1279871..1280740 - 870 WP_077408974.1 A24 family peptidase -
BZG29_RS05740 1280847..1282043 - 1197 WP_077399902.1 type II secretion system F family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-119)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 14993.29 Da        Isoelectric Point: 6.2252

>T72577 WP_077399893.1 NZ_CP019510:1277605-1278021 [Janthinobacterium sp. LM6]
MSAYLVDTDVIVAARKGSAAPEGVRAFFERVVPEMRYVPVQVIAQLRAGIQRSWRREAALEALALEGWLEAVLADYAPRL
LEFDLDCALVCARLHARGHAHGVDGQIAAMGIAYGLTVVSGRLDSFAAQGLRLENPFT

Download         Length: 417 bp

>T72577 NZ_CP019510:1277605-1278021 [Janthinobacterium sp. LM6]
ATGTCCGCCTACCTGGTCGACACGGATGTGATTGTTGCAGCGCGCAAGGGCAGCGCTGCGCCGGAGGGCGTGCGTGCTTT
TTTCGAACGGGTGGTGCCGGAAATGCGCTATGTGCCGGTGCAGGTGATCGCGCAGTTGCGCGCAGGCATACAGCGCAGCT
GGCGGCGCGAAGCGGCGCTGGAAGCACTGGCGCTGGAAGGCTGGCTGGAAGCCGTGCTGGCAGACTATGCGCCGCGGCTG
CTGGAATTCGACCTCGATTGCGCGCTCGTGTGCGCACGCCTGCATGCTCGCGGCCATGCGCATGGCGTCGATGGGCAGAT
CGCGGCGATGGGCATCGCCTATGGCTTGACGGTGGTCAGCGGCAGGCTCGACAGTTTCGCGGCGCAGGGGCTGCGCCTGG
AAAATCCGTTTACCTGA

Antitoxin


Download         Length: 70 a.a.        Molecular weight: 7928.13 Da        Isoelectric Point: 6.7248

>AT72577 WP_077399890.1 NZ_CP019510:1277389-1277598 [Janthinobacterium sp. LM6]
MPLTLTFTDTDELLIAALHKRARAHGRSIEDEHRDILRSALRPLPKRPLDDILRGMPDVGLDADFERRI

Download         Length: 210 bp

>AT72577 NZ_CP019510:1277389-1277598 [Janthinobacterium sp. LM6]
ATGCCGCTGACACTGACCTTTACCGATACCGATGAATTGCTGATTGCCGCCCTGCACAAGCGTGCCCGCGCGCATGGCCG
CAGCATCGAAGACGAACACCGCGACATTCTGCGCAGCGCCTTGCGGCCGCTGCCGAAGCGTCCGCTCGATGATATTCTGC
GCGGCATGCCCGACGTGGGGCTGGACGCGGATTTCGAGCGTCGCATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References