Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PP_4151-4152/excise(antitoxin)
Location 511615..512732 Replicon chromosome
Accession NZ_CP019510
Organism Janthinobacterium sp. LM6

Toxin (Protein)


Gene name PP_4152 Uniprot ID -
Locus tag BZG29_RS02215 Protein ID WP_077398566.1
Coordinates 512079..512732 (+) Length 218 a.a.

Antitoxin (Protein)


Gene name PP_4151 Uniprot ID -
Locus tag BZG29_RS02210 Protein ID WP_150131078.1
Coordinates 511615..512079 (+) Length 155 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BZG29_RS02190 507970..509289 + 1320 WP_171984923.1 AAA family ATPase -
BZG29_RS02195 509286..510752 + 1467 WP_077398560.1 hypothetical protein -
BZG29_RS02200 510810..511232 + 423 WP_077398562.1 DNA mismatch endonuclease Vsr -
BZG29_RS02210 511615..512079 + 465 WP_150131078.1 helix-turn-helix domain-containing protein Antitoxin
BZG29_RS02215 512079..512732 + 654 WP_077398566.1 PIN domain-containing protein Toxin
BZG29_RS02220 512961..515618 + 2658 WP_077408917.1 TonB-dependent receptor -
BZG29_RS02225 515806..517158 + 1353 WP_077398568.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(9-116)

Antitoxin

Helix-turn-helix domain, group 17

(85-132)


Sequences

Toxin        


Download         Length: 218 a.a.        Molecular weight: 24301.16 Da        Isoelectric Point: 5.6726

>T72576 WP_077398566.1 NZ_CP019510:512079-512732 [Janthinobacterium sp. LM6]
MAGYYRYTAVLDACVLYPAPLRDLLLSLAADGIFSARWTAQIQEEWQRNLLLKRPDLDPSALVRTSALMAEAVEDGVIDS
YEYLIDTLILPDPDDRHVLAAAIVGHADAIVTFNLKDFPDALMRGHNIEVLHPDDFLVAQYELAPIRMLSVVKENRARLR
KPPRSSAELIATYEAQGLPQLGKLLRSAIALLWRLLQQPGNSRSTALPPLKYLPPFF

Download         Length: 654 bp

>T72576 NZ_CP019510:512079-512732 [Janthinobacterium sp. LM6]
ATGGCCGGATACTACCGTTACACTGCCGTTCTCGATGCCTGTGTGTTATATCCTGCACCCTTGCGCGATCTATTGCTGAG
TTTGGCGGCGGACGGTATCTTCAGCGCGCGCTGGACAGCGCAGATACAGGAGGAGTGGCAACGCAACTTGCTGCTCAAGC
GACCTGATCTCGACCCTTCGGCGTTGGTGCGCACCAGCGCGCTGATGGCCGAGGCAGTGGAGGATGGCGTGATCGATTCT
TACGAATACCTGATCGATACCTTGATCTTGCCCGATCCGGACGACCGGCACGTTCTGGCGGCTGCTATCGTGGGACATGC
TGATGCCATCGTCACGTTCAATCTCAAGGATTTCCCGGACGCACTCATGCGCGGGCACAACATTGAAGTCTTGCACCCGG
ATGATTTTCTGGTGGCCCAGTATGAATTGGCCCCGATACGCATGCTCAGCGTCGTCAAGGAAAACCGGGCACGATTGCGC
AAACCGCCCAGATCCTCAGCCGAATTGATTGCCACCTACGAAGCGCAAGGCTTGCCGCAACTGGGCAAGTTGCTGCGTTC
CGCGATTGCTTTGCTCTGGCGTCTGCTTCAGCAACCCGGCAATAGCCGTTCCACCGCTCTTCCTCCCTTGAAATACCTGC
CTCCGTTTTTCTGA

Antitoxin


Download         Length: 155 a.a.        Molecular weight: 17371.91 Da        Isoelectric Point: 6.2479

>AT72576 WP_150131078.1 NZ_CP019510:511615-512079 [Janthinobacterium sp. LM6]
MSNVIDRLDNKEDLELAKAAQRCLVSALDHSRAVQIAVLEEGAQDLGDAPLLRLPPNVLRLFADVLGTLAQGKAVTVMPK
ELDVTTQEAAMYLNMSRPYLVRLFEAGKIPYHKVGTHRRLRFEDVVQYKDERKRRSEQALQALADQAQELEQGY

Download         Length: 465 bp

>AT72576 NZ_CP019510:511615-512079 [Janthinobacterium sp. LM6]
ATGTCGAATGTAATCGATCGTCTGGACAATAAAGAAGACCTGGAACTGGCGAAAGCGGCGCAGCGTTGCCTGGTCAGTGC
GCTCGATCATTCGCGTGCCGTGCAGATTGCCGTTCTGGAAGAGGGTGCGCAGGACCTGGGCGACGCCCCCTTGCTGCGCT
TGCCGCCGAATGTATTGCGCCTGTTTGCCGATGTGCTGGGCACCTTGGCGCAAGGGAAGGCCGTGACGGTCATGCCCAAG
GAGCTCGATGTAACGACCCAGGAAGCGGCGATGTATTTGAATATGTCACGGCCGTATCTGGTGCGCTTGTTTGAAGCGGG
GAAAATTCCCTATCATAAGGTGGGTACGCACCGCCGGCTGCGCTTTGAGGATGTGGTGCAGTACAAGGATGAGCGCAAAC
GGCGTTCGGAACAGGCCTTGCAAGCCTTGGCAGATCAGGCGCAGGAGCTTGAACAGGGGTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References