72572

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 2971296..2973007 Replicon chromosome
Accession NZ_CP019509
Organism Aquaspirillum sp. LM1

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag BXU06_RS12780 Protein ID WP_077300276.1
Coordinates 2972366..2973007 (-) Length 214 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag BXU06_RS12775 Protein ID WP_077300273.1
Coordinates 2971296..2972366 (-) Length 357 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BXU06_RS12745 2967205..2967726 + 522 WP_077300258.1 xanthine phosphoribosyltransferase -
BXU06_RS12750 2967728..2968924 - 1197 WP_077300261.1 urate hydroxylase PuuD -
BXU06_RS12755 2968924..2969277 - 354 WP_077300264.1 hydroxyisourate hydrolase -
BXU06_RS12760 2969511..2970029 + 519 WP_077302872.1 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase -
BXU06_RS12765 2970037..2970504 - 468 WP_077300267.1 cupin domain-containing protein -
BXU06_RS12770 2970569..2970997 - 429 WP_077300270.1 PaaI family thioesterase -
BXU06_RS12775 2971296..2972366 - 1071 WP_077300273.1 macro domain-containing protein Antitoxin
BXU06_RS12780 2972366..2973007 - 642 WP_077300276.1 DUF4433 domain-containing protein Toxin
BXU06_RS12785 2973161..2974135 - 975 WP_077302874.1 LysR family transcriptional regulator -
BXU06_RS12790 2974237..2977122 - 2886 WP_077300278.1 bifunctional diguanylate cyclase/phosphodiesterase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(14-213)

Antitoxin

Macro domain

(18-130)


Sequences

Toxin        


Download         Length: 214 a.a.        Molecular weight: 24614.14 Da        Isoelectric Point: 7.6105

>T72572 WP_077300276.1 NZ_CP019509:c2973007-2972366 [Aquaspirillum sp. LM1]
MRYTSLNPGKALIWRIVHRDNLPWILDHGLHCGNSAIHALQWVSIGHPELIGKRATHPVPLPPGGFLNDYVPFYFTPFSP
MLSNIHTGRGVQKRQNDEIVILVSSMHHLQQQGVSCLFTDSHAYYQWAQFYSNLADLDKIDWPLLQRRDFKRDADDPAKF
ERYQAEALVHQHLPVNGLLGIVCYTETLKQDIEQAVQIRQLNLPVHVRTGWYF

Download         Length: 642 bp

>T72572 NZ_CP019509:c2973007-2972366 [Aquaspirillum sp. LM1]
ATGCGCTATACCAGCCTCAACCCGGGAAAAGCCCTGATCTGGCGCATCGTTCATCGCGATAATCTGCCCTGGATTCTGGA
CCATGGCCTGCACTGCGGAAACAGTGCCATTCATGCCTTGCAGTGGGTGAGCATTGGCCATCCAGAGTTGATCGGCAAAC
GCGCCACCCATCCCGTGCCATTGCCACCCGGTGGGTTTTTGAACGACTATGTGCCGTTCTACTTCACCCCATTCTCGCCA
ATGCTGAGCAATATCCATACGGGCAGAGGGGTTCAGAAACGGCAAAATGACGAGATCGTGATTCTGGTCTCCAGCATGCA
TCATCTGCAGCAGCAAGGTGTGTCGTGTTTGTTTACCGATAGCCATGCCTACTACCAATGGGCACAGTTTTATTCCAACC
TCGCCGACCTCGATAAAATTGACTGGCCGCTGTTGCAGCGACGAGATTTTAAACGGGATGCGGATGATCCTGCCAAATTC
GAGCGTTACCAGGCTGAAGCGCTGGTTCATCAGCATCTGCCTGTCAATGGATTACTTGGCATCGTGTGCTACACCGAAAC
ACTGAAGCAAGACATTGAACAGGCCGTGCAAATCCGTCAGCTCAATCTGCCGGTGCATGTTCGAACAGGGTGGTATTTCT
GA

Antitoxin


Download         Length: 357 a.a.        Molecular weight: 40105.17 Da        Isoelectric Point: 7.7271

>AT72572 WP_077300273.1 NZ_CP019509:c2972366-2971296 [Aquaspirillum sp. LM1]
MITFTQGNLLEARSEALVNTVNTVGVMGKGIALMFKERFADNFRLYAAACKAQQVQTGKMFITQVNELEGPRWVVNFPTK
QHWRSPSQLSWVEEGLQDLRRFLLENQIKSIAIPPLGAGHGGLDWAEVRPCIEAALGDLDIDILVFEPTRQYQNIAKRTG
VAHLTPARALIAELVRRYWVPGMECSLLEIQKLAWFLERKIAQFGLPSLDLRFQAHKYGPYADRLRHLLTGLDGSYLHCE
KRISDASPLDVIWFDDSRKTVLQTYLKTEASEYTPALEASATLIDGFESPFGMELLATVDWLLCRNGVPPSVPALREGLR
HWQGGPDAAARKVRLFNDRALEIALTRLRYDAARSA

Download         Length: 1071 bp

>AT72572 NZ_CP019509:c2972366-2971296 [Aquaspirillum sp. LM1]
ATGATTACGTTTACACAAGGTAATTTACTGGAGGCCCGCAGCGAGGCGCTGGTCAACACGGTCAACACCGTGGGCGTCAT
GGGCAAGGGCATTGCGCTGATGTTCAAAGAGCGCTTTGCTGACAATTTTCGTTTGTACGCCGCTGCATGCAAAGCGCAGC
AAGTACAAACCGGCAAGATGTTCATCACCCAGGTCAACGAACTGGAAGGGCCTCGTTGGGTGGTGAACTTTCCCACCAAA
CAGCACTGGCGCTCACCGTCGCAGTTGAGCTGGGTGGAAGAGGGCTTGCAGGATTTGCGTCGCTTTTTGCTGGAAAACCA
GATCAAGTCGATCGCGATTCCTCCACTGGGGGCCGGTCATGGCGGACTGGACTGGGCGGAAGTCAGGCCATGCATTGAAG
CAGCGTTGGGTGATCTCGATATCGACATCCTGGTGTTTGAACCCACCAGGCAGTACCAGAATATCGCCAAACGCACAGGC
GTTGCACACCTCACGCCCGCACGCGCCTTAATTGCCGAACTGGTGCGGCGCTACTGGGTGCCTGGTATGGAATGCAGCCT
GCTGGAAATTCAGAAGCTTGCCTGGTTTCTGGAGCGCAAGATTGCACAGTTTGGCCTGCCATCCCTGGATCTACGCTTTC
AAGCGCACAAATATGGGCCATACGCTGACCGTTTGCGCCATCTGCTGACAGGGCTGGATGGCAGCTATCTGCACTGCGAA
AAACGTATCAGTGATGCAAGTCCCCTGGATGTGATCTGGTTTGACGATAGCCGCAAAACCGTATTGCAAACCTATCTGAA
AACCGAAGCCAGTGAGTACACTCCCGCGCTGGAGGCTAGCGCTACGCTGATTGATGGCTTTGAGTCACCATTTGGCATGG
AATTGCTGGCCACGGTAGATTGGCTGTTGTGTCGTAACGGTGTTCCCCCCTCTGTGCCAGCGCTGCGCGAGGGTCTGCGC
CATTGGCAAGGCGGCCCCGACGCAGCGGCGCGCAAAGTCCGGCTATTTAACGATCGTGCACTGGAGATTGCGTTGACGCG
TTTACGTTACGACGCAGCCAGATCAGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References