Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/GNAT-DUF1778
Location 2880515..2881296 Replicon chromosome
Accession NZ_CP019509
Organism Aquaspirillum sp. LM1

Toxin (Protein)


Gene name tacT Uniprot ID -
Locus tag BXU06_RS12335 Protein ID WP_077300026.1
Coordinates 2880790..2881296 (+) Length 169 a.a.

Antitoxin (Protein)


Gene name tacA Uniprot ID -
Locus tag BXU06_RS12330 Protein ID WP_077300023.1
Coordinates 2880515..2880793 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BXU06_RS12300 2875756..2876601 + 846 WP_171982217.1 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase -
BXU06_RS12310 2876768..2877724 + 957 WP_077300012.1 ribose-phosphate pyrophosphokinase -
BXU06_RS12315 2877834..2878394 + 561 WP_077300015.1 50S ribosomal protein L25/general stress protein Ctc -
BXU06_RS12320 2878501..2879070 + 570 WP_077300017.1 aminoacyl-tRNA hydrolase -
BXU06_RS12325 2879115..2880206 + 1092 WP_077300020.1 redox-regulated ATPase YchF -
BXU06_RS12330 2880515..2880793 + 279 WP_077300023.1 DUF1778 domain-containing protein Antitoxin
BXU06_RS12335 2880790..2881296 + 507 WP_077300026.1 GNAT family N-acetyltransferase Toxin
BXU06_RS12340 2881634..2884837 - 3204 WP_077300029.1 type I restriction endonuclease subunit R -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-145)

Antitoxin

Vibrio phage ICP1, Orf50

(11-86)


Sequences

Toxin        


Download         Length: 169 a.a.        Molecular weight: 18272.01 Da        Isoelectric Point: 7.2632

>T72571 WP_077300026.1 NZ_CP019509:2880790-2881296 [Aquaspirillum sp. LM1]
MSAAYESVRKLTPADSTEGFDCGQAPLNQFLQRYALVNQQANSAQTYVCCLGGQVVGFYSLAVGSIDPQGTPARVMKGLA
RHPVPVMILARLAVDRDHQGQGLGKALLKDALLRTAQAADIAGIRCLLVHAKDEAARQWYESWEFDPSPTDPYHLFLMLK
DLKALLAG

Download         Length: 507 bp

>T72571 NZ_CP019509:2880790-2881296 [Aquaspirillum sp. LM1]
TTGAGTGCAGCGTATGAGTCCGTCCGCAAGCTCACGCCTGCGGACTCGACCGAAGGCTTTGACTGCGGGCAAGCGCCACT
CAACCAGTTTTTGCAACGCTACGCTCTGGTCAACCAGCAAGCCAACAGCGCCCAGACTTATGTGTGCTGCCTTGGCGGCC
AGGTCGTGGGCTTCTACAGTCTGGCGGTTGGAAGTATTGATCCGCAGGGCACCCCAGCGCGCGTCATGAAGGGCTTGGCC
CGGCATCCCGTGCCGGTCATGATCCTGGCGCGGTTGGCCGTGGATCGTGATCACCAGGGACAGGGTCTGGGCAAGGCGCT
GCTCAAGGACGCGCTGCTGCGCACCGCACAGGCCGCTGACATTGCGGGCATTCGCTGCCTGCTGGTTCATGCCAAGGATG
AGGCCGCGCGGCAGTGGTATGAGTCCTGGGAGTTCGACCCCAGTCCGACCGACCCTTATCATCTGTTCTTGATGCTCAAG
GATCTCAAGGCGCTACTGGCGGGTTGA

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10148.61 Da        Isoelectric Point: 8.5493

>AT72571 WP_077300023.1 NZ_CP019509:2880515-2880793 [Aquaspirillum sp. LM1]
MSASNLSKTERIDVRASSAVKQLLQEAARSCHKNVSEFLLDAGVIAANQALADRRCFVLDDEQWQAFQQALDRPVQAKPR
LKKLLSEPGVLG

Download         Length: 279 bp

>AT72571 NZ_CP019509:2880515-2880793 [Aquaspirillum sp. LM1]
ATGAGCGCCTCGAATCTCTCTAAAACCGAACGGATCGATGTCCGCGCCAGCAGTGCGGTCAAACAGTTGCTGCAGGAGGC
TGCGCGCTCTTGCCATAAAAACGTCAGTGAATTCCTGCTGGATGCCGGGGTGATCGCGGCCAACCAAGCATTGGCAGACC
GTCGTTGCTTTGTGCTGGACGATGAGCAGTGGCAGGCGTTTCAGCAGGCGCTGGATCGTCCCGTGCAAGCCAAGCCGCGC
TTGAAGAAACTGCTCAGTGAACCTGGGGTTCTGGGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References