Detailed information of TA system TA072569

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PP_4151-4152/excise(antitoxin)
• Location: 1328991..1330030
• Replicon: chromosome
• Accession: NZ_CP019509
• Organism: Aquaspirillum sp. LM1

Toxin (Protein)

• Gene name: PP_4152
• Uniprot ID: -
• Locus tag: BXU06_RS05750
• Protein ID: WP_077297674.1
• Coordinates: 1328991..1329560 (-)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: PP_4151
• Uniprot ID: -
• Locus tag: BXU06_RS05755
• Protein ID: WP_077297676.1
• Coordinates: 1329557..1330030 (-)
• Length: 158 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BXU06_RS05735	1324570..1325196	-	627	WP_077297669.1	TetR family transcriptional regulator C-terminal domain-containing protein	-
BXU06_RS17650	1325239..1325403	+	165	WP_171982121.1	hypothetical protein	-
BXU06_RS05745	1325600..1328521	+	2922	WP_171982122.1	DUF4062 domain-containing protein	-
BXU06_RS05750	1328991..1329560	-	570	WP_077297674.1	PIN domain-containing protein	Toxin
BXU06_RS05755	1329557..1330030	-	474	WP_077297676.1	helix-turn-helix domain-containing protein	Antitoxin
BXU06_RS05760	1330172..1330480	-	309	WP_150125118.1	hypothetical protein	-
BXU06_RS05765	1330570..1333806	+	3237	WP_077297680.1	TIR domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (6-112)

Antitoxin

• SinI-like, DNA-binding domain (84-129)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21978.40 Da
• Isoelectric Point: 6.8303

>T72569 WP_077297674.1 NZ_CP019509:c1329560-1328991 [Aquaspirillum sp. LM1]
VSVFTVIYDACVLYPAPLRDILLQLATTDLFRARWTARIHDEWMRNALKNHPTMCPETLQRTRALMDSHVRDALITGYEY
LESRLHLPDHDDRHVLAAAIHGQADAIVTFNLRDFPDEKLAPHRVEAINPDDFLMDLWDLDKARVLMSVQTVRARLKRPP
LTADEYIALILRQRLPQFAHVLREFHALI

Nucleotide

• Length: 570 bp

>T72569 NZ_CP019509:c1329560-1328991 [Aquaspirillum sp. LM1]
GTGAGCGTGTTCACCGTCATTTACGACGCCTGCGTGCTATACCCGGCGCCATTGCGTGACATCCTGTTGCAACTGGCGAC
TACCGACCTGTTTCGGGCTCGCTGGACTGCCCGCATTCATGATGAGTGGATGAGAAATGCGCTGAAAAACCACCCCACGA
TGTGTCCCGAAACTTTGCAGCGCACTCGGGCATTGATGGACAGCCATGTCCGTGATGCGCTGATTACTGGGTATGAATAC
TTGGAGTCGCGGTTGCACCTGCCAGATCACGATGACAGGCATGTGCTGGCAGCGGCCATTCATGGGCAAGCCGATGCGAT
AGTGACGTTCAACTTGCGGGATTTTCCGGACGAGAAGCTGGCGCCACATAGGGTTGAGGCGATCAACCCCGATGATTTCT
TGATGGACCTATGGGACTTGGATAAAGCCAGGGTGCTGATGTCGGTGCAAACGGTTCGGGCTCGCCTCAAGCGCCCGCCA
TTGACCGCAGACGAGTATATCGCGCTGATCTTGCGCCAGCGTTTGCCACAGTTTGCGCATGTGTTGCGTGAATTTCATGC
GTTGATTTGA

Antitoxin

Protein

• Length: 158 a.a.
• Molecular weight: 17189.74 Da
• Isoelectric Point: 6.4908

>AT72569 WP_077297676.1 NZ_CP019509:c1330030-1329557 [Aquaspirillum sp. LM1]
MNTLVRDMPLLPTEAETLLARKSASALSVHLASCHAPQSIVIIDHAGEKQAVELPSAVYPLLLDALAEIARGNAVTLTPV
HAELTTQEAADLLNVSRPYLVKLLDEGKIPHRKVGRHRRVLYRDMLDYKQRTDSQRSQALDELAAMAQEAGMGYAGE

Nucleotide

• Length: 474 bp

>AT72569 NZ_CP019509:c1330030-1329557 [Aquaspirillum sp. LM1]
ATGAATACGCTTGTTCGCGATATGCCGCTTCTTCCCACCGAAGCAGAAACCTTGCTCGCTCGCAAAAGCGCCAGCGCCTT
GTCGGTGCATCTGGCCAGTTGCCATGCCCCGCAAAGCATTGTGATTATTGATCATGCTGGCGAAAAGCAGGCTGTCGAGC
TGCCTTCGGCGGTTTACCCGTTGTTGCTGGATGCGCTGGCCGAGATTGCCCGTGGCAATGCCGTCACCTTGACGCCTGTG
CATGCCGAGCTGACCACGCAGGAAGCCGCTGACCTGCTGAATGTGTCGCGCCCTTATCTGGTCAAGCTGCTGGATGAAGG
CAAGATCCCCCATCGCAAGGTGGGCCGCCATCGCCGGGTGCTGTATCGCGATATGCTGGACTACAAACAGCGCACCGATA
GCCAGCGCAGCCAGGCTTTGGATGAGTTGGCGGCCATGGCGCAAGAAGCCGGCATGGGCTATGCGGGAGAGTGA