Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 2504040..2504695 Replicon chromosome
Accession NZ_CP019508
Organism Brevundimonas sp. LM2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BZG35_RS12375 Protein ID WP_077355931.1
Coordinates 2504040..2504441 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BZG35_RS12380 Protein ID WP_077355932.1
Coordinates 2504438..2504695 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BZG35_RS12360 2499461..2499886 + 426 WP_077355928.1 DUF2147 domain-containing protein -
BZG35_RS12365 2500137..2502902 + 2766 WP_077355929.1 TonB-dependent receptor -
BZG35_RS12370 2502989..2503978 - 990 WP_077355930.1 aldo/keto reductase -
BZG35_RS12375 2504040..2504441 - 402 WP_077355931.1 type II toxin-antitoxin system VapC family toxin Toxin
BZG35_RS12380 2504438..2504695 - 258 WP_077355932.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
BZG35_RS12385 2504730..2506541 - 1812 WP_077355933.1 aminopeptidase P family protein -
BZG35_RS17685 2506592..2507074 - 483 WP_150126024.1 hypothetical protein -
BZG35_RS12395 2507127..2507996 - 870 WP_077355935.1 50S ribosomal protein L11 methyltransferase -
BZG35_RS17690 2508002..2508232 - 231 WP_150126025.1 hypothetical protein -
BZG35_RS12405 2508243..2508707 + 465 WP_150126026.1 hypothetical protein -
BZG35_RS12410 2508781..2508993 - 213 WP_077355938.1 DUF3126 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-128)

Antitoxin

Antitoxin VapB-like

(2-66)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14183.38 Da        Isoelectric Point: 8.0069

>T72566 WP_077355931.1 NZ_CP019508:c2504441-2504040 [Brevundimonas sp. LM2]
VIVDTSAIVAIIRNEPEKDLFSGRLVGARSAGEATRISAATLVELTTVVDRYKEARASRLLDALLAELRLEVVPVDGALA
VVARAANLKFGKGFHPARLNLGDCFAYALAKQTGERLLFKGSDFAQTDIVSAV

Download         Length: 402 bp

>T72566 NZ_CP019508:c2504441-2504040 [Brevundimonas sp. LM2]
GTGATCGTGGACACGTCGGCGATCGTGGCGATCATTCGGAACGAGCCAGAAAAGGATCTGTTCTCCGGTCGGCTGGTCGG
CGCTCGATCCGCCGGAGAAGCGACACGGATCTCGGCGGCGACCCTGGTCGAGCTGACCACCGTGGTGGATCGTTACAAGG
AAGCAAGGGCCTCTCGTCTTCTCGACGCTCTCCTCGCGGAGCTGCGGCTCGAAGTGGTTCCGGTCGATGGCGCGCTTGCA
GTGGTCGCCCGTGCCGCGAACCTCAAATTCGGAAAGGGCTTTCATCCCGCCCGCCTGAACCTCGGTGACTGCTTCGCCTA
TGCGCTCGCCAAACAGACTGGCGAGCGCCTGCTGTTCAAGGGCAGCGACTTTGCACAGACGGACATCGTTTCGGCCGTCT
GA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9344.67 Da        Isoelectric Point: 4.3135

>AT72566 WP_077355932.1 NZ_CP019508:c2504695-2504438 [Brevundimonas sp. LM2]
MLNIKNPIAHELAVEVAAATGESLTDAVIVALRERRDRLKANPRGIDIDKVEAILAEMRAALPKEFFEEEDPSAFLYDPE
TGLPA

Download         Length: 258 bp

>AT72566 NZ_CP019508:c2504695-2504438 [Brevundimonas sp. LM2]
ATGCTCAATATCAAGAACCCCATCGCGCATGAGTTGGCAGTGGAGGTCGCAGCAGCGACGGGCGAGAGCCTGACCGACGC
TGTCATCGTCGCGTTGAGGGAGCGGCGTGATCGCCTGAAGGCCAATCCCCGCGGGATCGACATCGACAAGGTCGAGGCCA
TTCTGGCCGAGATGCGCGCGGCCCTGCCGAAAGAGTTCTTCGAGGAGGAAGACCCCAGCGCGTTTCTCTACGACCCGGAG
ACGGGTCTGCCGGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References