Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 297321..297775 Replicon chromosome
Accession NZ_CP019508
Organism Brevundimonas sp. LM2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BZG35_RS01525 Protein ID WP_077354032.1
Coordinates 297321..297596 (-) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag BZG35_RS01530 Protein ID WP_077354033.1
Coordinates 297596..297775 (-) Length 60 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BZG35_RS01500 293993..294445 - 453 WP_077354028.1 DUF3576 domain-containing protein -
BZG35_RS01505 294811..295206 + 396 WP_077354029.1 hypothetical protein -
BZG35_RS01510 295203..295853 - 651 WP_077357723.1 thiamine phosphate synthase -
BZG35_RS01515 295852..296577 + 726 WP_077354030.1 YggS family pyridoxal phosphate-dependent enzyme -
BZG35_RS01520 296638..297324 + 687 WP_077354031.1 response regulator transcription factor -
BZG35_RS01525 297321..297596 - 276 WP_077354032.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
BZG35_RS01530 297596..297775 - 180 WP_077354033.1 stability determinant Antitoxin
BZG35_RS01535 297821..298615 - 795 WP_077354034.1 exodeoxyribonuclease III -
BZG35_RS01540 298865..299500 - 636 WP_077357724.1 outer membrane lipoprotein carrier protein LolA -
BZG35_RS01545 299852..302263 - 2412 WP_077354035.1 DNA translocase FtsK -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10486.09 Da        Isoelectric Point: 10.6845

>T72564 WP_077354032.1 NZ_CP019508:c297596-297321 [Brevundimonas sp. LM2]
MSHVAWDKRARSDLSTAITYIAARNPDAAQSLKSMIETATERLSAFPYLHRVGRTPGTREMVVHPNYIVIYRVETNVIRI
LRVLHARQHYP

Download         Length: 276 bp

>T72564 NZ_CP019508:c297596-297321 [Brevundimonas sp. LM2]
ATGTCACACGTCGCCTGGGATAAGCGGGCGCGATCAGACCTTTCTACCGCGATCACCTATATCGCAGCCCGCAATCCCGA
CGCGGCCCAATCTCTGAAGTCCATGATCGAGACCGCAACCGAACGCCTGTCCGCCTTTCCGTATCTGCACAGGGTCGGAC
GGACGCCGGGCACCCGGGAGATGGTCGTCCATCCGAACTACATCGTTATCTATCGTGTGGAGACGAACGTGATCCGAATT
TTGCGCGTCCTGCACGCGAGACAACACTACCCTTAA

Antitoxin


Download         Length: 60 a.a.        Molecular weight: 6468.19 Da        Isoelectric Point: 4.1933

>AT72564 WP_077354033.1 NZ_CP019508:c297775-297596 [Brevundimonas sp. LM2]
MPALSPIESEFASTEEAAAHDAWFRAKVQEALDDPSEPIPHDQVMAELQSIIDAHKPKA

Download         Length: 180 bp

>AT72564 NZ_CP019508:c297775-297596 [Brevundimonas sp. LM2]
ATGCCTGCCCTGTCGCCCATCGAATCCGAGTTTGCCTCGACTGAAGAGGCTGCAGCCCATGACGCCTGGTTCCGCGCCAA
GGTACAGGAGGCGCTTGATGATCCCAGCGAACCCATTCCGCACGACCAGGTGATGGCGGAGCTGCAGTCCATCATCGACG
CCCACAAACCGAAGGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References