72563

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-paaA/RelE(toxin)
Location 137819..138271 Replicon chromosome
Accession NZ_CP019508
Organism Brevundimonas sp. LM2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BZG35_RS00650 Protein ID WP_077353851.1
Coordinates 137996..138271 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name paaA Uniprot ID -
Locus tag BZG35_RS00645 Protein ID WP_077353849.1
Coordinates 137819..137992 (+) Length 58 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BZG35_RS00620 133179..134297 + 1119 WP_077353841.1 helix-turn-helix domain-containing protein -
BZG35_RS00625 134320..135504 + 1185 WP_077353843.1 flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase -
BZG35_RS00630 135612..136193 + 582 WP_077353844.1 hypothetical protein -
BZG35_RS17800 136238..136723 - 486 WP_171981844.1 hypothetical protein -
BZG35_RS17805 136908..137768 + 861 WP_171981845.1 alpha/beta hydrolase -
BZG35_RS00645 137819..137992 + 174 WP_077353849.1 stability determinant Antitoxin
BZG35_RS00650 137996..138271 + 276 WP_077353851.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BZG35_RS00655 138375..139154 - 780 WP_077353853.1 sulfite exporter TauE/SafE family protein -
BZG35_RS00660 139365..139676 + 312 WP_077353855.1 hypothetical protein -
BZG35_RS00665 139758..140825 + 1068 WP_077353857.1 peptide chain release factor 1 -
BZG35_RS00670 140887..141603 + 717 WP_077353858.1 heme ABC transporter permease CcmC -
BZG35_RS00675 141603..141797 + 195 WP_077353860.1 heme exporter protein CcmD -
BZG35_RS00680 141794..142384 + 591 WP_077353862.1 DsbE family thiol:disulfide interchange protein -
BZG35_RS00685 142456..142704 + 249 WP_077353864.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10204.52 Da        Isoelectric Point: 5.0893

>T72563 WP_077353851.1 NZ_CP019508:137996-138271 [Brevundimonas sp. LM2]
VAVVAWTDEAFDDLDAISLYIGTRNPAAADRLAETIWTAAERLGERPFAYRAGREPGTREAVVHPNYTMVYAVGLETIRI
LRVLHTSREYP

Download         Length: 276 bp

>T72563 NZ_CP019508:137996-138271 [Brevundimonas sp. LM2]
GTGGCGGTCGTCGCCTGGACCGATGAGGCCTTCGACGATCTGGATGCCATCAGCCTGTATATTGGCACTCGGAATCCAGC
GGCGGCCGATAGGTTGGCAGAGACGATATGGACTGCGGCCGAACGATTGGGCGAGCGACCCTTCGCCTACCGGGCCGGCC
GAGAGCCCGGAACGCGGGAAGCTGTCGTCCACCCCAACTATACCATGGTCTACGCCGTAGGCCTCGAGACCATCAGGATC
CTGCGCGTCCTCCACACCAGCCGCGAATACCCCTGA

Antitoxin


Download         Length: 58 a.a.        Molecular weight: 6279.13 Da        Isoelectric Point: 4.6286

>AT72563 WP_077353849.1 NZ_CP019508:137819-137992 [Brevundimonas sp. LM2]
MPALDPIVSEFASTEDEAAYDVWFRAKVREALANPGPDIPHDEVVARIKARLASLKT

Download         Length: 174 bp

>AT72563 NZ_CP019508:137819-137992 [Brevundimonas sp. LM2]
ATGCCCGCCCTGGACCCTATCGTTTCCGAGTTCGCCTCGACCGAGGATGAGGCCGCCTATGACGTGTGGTTCCGCGCCAA
GGTGCGAGAGGCTTTAGCCAACCCTGGTCCCGATATTCCCCATGACGAGGTGGTTGCCAGGATCAAGGCCCGTCTCGCGT
CGCTGAAAACGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References