Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 787578..788086 Replicon chromosome
Accession NZ_CP019448
Organism Simonsiella muelleri ATCC 29453

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BWP33_RS03865 Protein ID WP_104930313.1
Coordinates 787578..787838 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag BWP33_RS03870 Protein ID WP_104930314.1
Coordinates 787829..788086 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BWP33_RS03850 784688..785389 + 702 WP_002643086.1 type IV secretion system protein -
BWP33_RS03855 785386..786207 + 822 WP_002643087.1 TrbG/VirB9 family P-type conjugative transfer protein -
BWP33_RS03860 786220..787530 + 1311 WP_002643088.1 type IV secretion system protein VirB10 -
BWP33_RS03865 787578..787838 - 261 WP_104930313.1 Txe/YoeB family addiction module toxin Toxin
BWP33_RS03870 787829..788086 - 258 WP_104930314.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
BWP33_RS03875 788150..789214 + 1065 Protein_752 P-type DNA transfer ATPase VirB11 -
BWP33_RS03880 789264..789458 + 195 WP_002641864.1 hypothetical protein -
BWP33_RS03885 789448..789720 + 273 WP_002641863.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family -
BWP33_RS03890 789816..790817 + 1002 WP_002641862.1 IS5 family transposase -
BWP33_RS03895 790955..791401 - 447 Protein_756 lytic transglycosylase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10501.98 Da        Isoelectric Point: 7.2761

>T72474 WP_104930313.1 NZ_CP019448:c787838-787578 [Simonsiella muelleri ATCC 29453]
MRLTFSDDAWDDYIFWQTTDRKILKRINTLIKDIKRNPFDGIGKPEPLRFHLSGFWSRRIDEEHRLVYAIENEQILIASC
RYHYVE

Download         Length: 261 bp

>T72474 NZ_CP019448:c787838-787578 [Simonsiella muelleri ATCC 29453]
ATGCGATTAACTTTTTCTGATGATGCATGGGACGATTATATTTTTTGGCAAACGACAGACCGAAAAATATTAAAACGCAT
CAACACATTAATTAAAGACATCAAACGCAACCCTTTTGACGGCATTGGTAAACCCGAACCCTTACGGTTTCATTTGTCAG
GCTTTTGGTCGCGTAGGATTGATGAAGAACATCGGTTGGTCTATGCAATTGAAAATGAACAAATTTTGATTGCTTCGTGT
CGGTATCATTACGTGGAATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9911.26 Da        Isoelectric Point: 7.1332

>AT72474 WP_104930314.1 NZ_CP019448:c788086-787829 [Simonsiella muelleri ATCC 29453]
MYTLTYSEARQNLAKTMQEVVQNHEPVLITRAKNEDCVLMSLSHYRSLEETAYLLRSPANAKRLQRSIEQLRQNGGKERE
LIECD

Download         Length: 258 bp

>AT72474 NZ_CP019448:c788086-787829 [Simonsiella muelleri ATCC 29453]
ATGTATACCTTAACTTATTCGGAAGCCCGTCAAAATCTTGCTAAAACCATGCAAGAAGTCGTTCAAAATCATGAGCCTGT
CTTAATCACACGCGCCAAAAATGAAGATTGTGTTTTGATGTCGCTGTCGCATTACCGTTCTTTGGAAGAAACGGCATATT
TGTTGCGTTCTCCAGCCAATGCCAAGCGTTTGCAGCGTTCTATTGAACAATTGCGTCAAAATGGTGGTAAGGAACGGGAA
CTGATTGAATGCGATTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References