72433

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 1918956..1919475 Replicon chromosome
Accession NZ_CP019428
Organism Pseudomonas sp. R76

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PspR76_RS08735 Protein ID WP_159954833.1
Coordinates 1918956..1919246 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PspR76_RS08740 Protein ID WP_159954834.1
Coordinates 1919236..1919475 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PspR76_RS08705 1914366..1914926 - 561 WP_003172487.1 glycine cleavage system protein R -
PspR76_RS08710 1915200..1916078 + 879 WP_159954830.1 4-hydroxy-tetrahydrodipicolinate synthase -
PspR76_RS08715 1916096..1917211 + 1116 WP_159954831.1 outer membrane protein assembly factor BamC -
PspR76_RS08720 1917216..1917974 + 759 WP_159954832.1 MBL fold metallo-hydrolase -
PspR76_RS08725 1918002..1918715 + 714 WP_010212191.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
PspR76_RS08735 1918956..1919246 - 291 WP_159954833.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PspR76_RS08740 1919236..1919475 - 240 WP_159954834.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PspR76_RS08745 1919819..1921045 - 1227 WP_159954835.1 MFS transporter -
PspR76_RS08750 1921328..1921582 + 255 WP_159954836.1 hypothetical protein -
PspR76_RS08755 1921730..1922287 + 558 WP_159954837.1 cytochrome b -
PspR76_RS08760 1922322..1922873 + 552 WP_174245597.1 hypothetical protein -
PspR76_RS08765 1922934..1923431 + 498 WP_159961367.1 RNA polymerase sigma factor -
PspR76_RS08770 1923428..1924195 + 768 WP_159954838.1 transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-73)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11319.15 Da        Isoelectric Point: 9.9154

>T72433 WP_159954833.1 NZ_CP019428:c1919246-1918956 [Pseudomonas sp. R76]
MTYSLDFDARALKEWQKLGDTLRQQLKKKLVEILKNPRIEANRLHDLPDCYKIKLRSSGYRLVYQVIDQEITVVVVAIGK
REREQAYRIAGERLSE

Download         Length: 291 bp

>T72433 NZ_CP019428:c1919246-1918956 [Pseudomonas sp. R76]
ATGACCTATAGCCTTGATTTCGATGCGCGAGCATTGAAGGAGTGGCAAAAGCTAGGCGACACCCTTCGTCAGCAGCTCAA
GAAGAAGCTAGTGGAAATTCTGAAAAACCCACGTATTGAAGCTAATCGCCTGCATGACCTGCCCGACTGCTACAAAATCA
AGCTGCGTAGCAGCGGTTACAGGCTGGTTTATCAAGTGATCGATCAGGAAATCACTGTGGTGGTGGTGGCCATCGGTAAG
CGGGAACGCGAGCAGGCTTATCGTATAGCGGGCGAACGTTTGAGCGAGTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8958.42 Da        Isoelectric Point: 4.5881

>AT72433 WP_159954834.1 NZ_CP019428:c1919475-1919236 [Pseudomonas sp. R76]
MASISIRIDDDLKARAYLELEKLGVTPSELMRQALQYVADRGQLPFKPVLMTEEDEALMAIVRERLASPQRVKVSIDDL

Download         Length: 240 bp

>AT72433 NZ_CP019428:c1919475-1919236 [Pseudomonas sp. R76]
ATGGCGTCTATAAGTATCCGTATCGATGACGACCTGAAAGCGCGCGCCTATCTCGAATTGGAAAAGCTCGGCGTTACGCC
TTCAGAACTGATGCGCCAGGCCCTGCAATACGTAGCGGATCGCGGCCAACTGCCGTTCAAGCCTGTTCTGATGACCGAGG
AAGATGAAGCGTTGATGGCCATCGTTCGGGAACGATTGGCATCTCCTCAACGGGTAAAGGTTTCTATAGATGACCTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References