Detailed information of TA system TA072430

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 5572934..5573450
• Replicon: chromosome
• Accession: NZ_CP019427
• Organism: Pseudomonas sp. S04

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PspS04_RS25000
• Protein ID: WP_159998235.1
• Coordinates: 5572934..5573221 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: PspS04_RS25005
• Protein ID: WP_159998237.1
• Coordinates: 5573211..5573450 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PspS04_RS24990	5568473..5572216	+	3744	WP_159998233.1	bifunctional diguanylate cyclase/phosphodiesterase	-
PspS04_RS25000	5572934..5573221	-	288	WP_159998235.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PspS04_RS25005	5573211..5573450	-	240	WP_159998237.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
PspS04_RS25010	5573771..5574025	-	255	Protein_4902	HipA N-terminal domain-containing protein	-
PspS04_RS25015	5574025..5574222	-	198	WP_159998926.1	transcriptional regulator	-
PspS04_RS25020	5574492..5575286	+	795	WP_095170607.1	lipopolysaccharide biosynthesis protein	-
PspS04_RS25025	5575377..5575838	+	462	WP_095170609.1	Lrp/AsnC family transcriptional regulator	-
PspS04_RS25030	5575979..5577661	+	1683	WP_095170611.1	NAD(P)/FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-79)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11263.19 Da
• Isoelectric Point: 10.2588

>T72430 WP_159998235.1 NZ_CP019427:c5573221-5572934 [Pseudomonas sp. S04]
MTYSLEFDARALKEWHKLGDTVRQQLKKKLATILVNPRIEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVMVFVVAVDK
REREQVYRKAVERLS

Nucleotide

• Length: 288 bp

>T72430 NZ_CP019427:c5573221-5572934 [Pseudomonas sp. S04]
ATGACCTATAGCCTTGAGTTCGATGCGCGGGCGTTAAAGGAGTGGCACAAACTGGGGGATACCGTTCGCCAGCAACTCAA
GAAGAAACTGGCTACGATCCTGGTCAATCCGCGTATTGAAGCCAACCGTCTGCATGCGTTGCCCGACTGCTACAAGATCA
AGTTGCGTAGCAGCGGCTATCGGCTGGTTTATCAAGTGATCGACCAAGAGGTCATGGTGTTTGTGGTGGCCGTTGATAAG
CGCGAGCGTGAGCAGGTTTATCGTAAAGCGGTTGAGCGGTTGAGCTAG

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8949.32 Da
• Isoelectric Point: 4.7962

>AT72430 WP_159998237.1 NZ_CP019427:c5573450-5573211 [Pseudomonas sp. S04]
MASINVRIDDDLKARAYHELEKLGVTPSELMRQALQYVAERGQLPFKPVLMTEDDEALIATVRERLAAPQRVKVSLDDL

Nucleotide

• Length: 240 bp

>AT72430 NZ_CP019427:c5573450-5573211 [Pseudomonas sp. S04]
ATGGCATCCATCAATGTCCGTATCGACGACGACCTCAAGGCGCGTGCTTACCACGAGCTGGAAAAACTCGGCGTCACCCC
GTCTGAGTTGATGCGCCAAGCCTTGCAGTACGTGGCAGAGCGCGGTCAGCTACCCTTCAAGCCCGTCCTGATGACCGAGG
ACGATGAAGCCTTGATCGCTACGGTGCGCGAGCGACTGGCTGCTCCCCAGCGGGTTAAGGTTTCACTAGATGACCTATAG