Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 3125034..3125581 Replicon chromosome
Accession NZ_CP019427
Organism Pseudomonas sp. S04

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PspS04_RS13830 Protein ID WP_159995940.1
Coordinates 3125306..3125581 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PspS04_RS13825 Protein ID WP_095170298.1
Coordinates 3125034..3125306 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PspS04_RS13805 3120515..3121933 + 1419 WP_159995932.1 aminotransferase -
PspS04_RS13810 3121987..3122838 + 852 WP_159995934.1 LuxR family transcriptional regulator -
PspS04_RS13815 3122848..3123219 - 372 WP_159995936.1 hypothetical protein -
PspS04_RS13820 3123224..3124738 - 1515 WP_159995938.1 hypothetical protein -
PspS04_RS13825 3125034..3125306 + 273 WP_095170298.1 ribbon-helix-helix domain-containing protein Antitoxin
PspS04_RS13830 3125306..3125581 + 276 WP_159995940.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PspS04_RS13835 3125676..3126503 - 828 WP_159995942.1 phosphonoacetaldehyde hydrolase -
PspS04_RS13840 3126586..3127458 - 873 WP_095170278.1 LysR family transcriptional regulator -
PspS04_RS13845 3127499..3128794 - 1296 WP_095170279.1 MFS transporter -
PspS04_RS13850 3128922..3130013 - 1092 WP_159995944.1 iron-containing alcohol dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10735.34 Da        Isoelectric Point: 9.5570

>T72429 WP_159995940.1 NZ_CP019427:3125306-3125581 [Pseudomonas sp. S04]
MELKWTSKGLSDIARLYEFLAAVNQPAAAHTIQQLTAAPRTLLTNPRIGERLEEFQPRDVRRIIIGHYEMRYEIQGSTLY
LLRLWHTREDR

Download         Length: 276 bp

>T72429 NZ_CP019427:3125306-3125581 [Pseudomonas sp. S04]
ATGGAGTTGAAGTGGACCAGCAAGGGGCTTTCCGACATTGCCCGGCTGTATGAGTTTCTGGCCGCGGTGAACCAGCCCGC
CGCCGCGCATACGATTCAACAGCTCACGGCTGCTCCTCGTACGTTGCTGACAAATCCACGCATTGGCGAACGGCTTGAAG
AGTTCCAGCCACGGGATGTGCGCCGAATTATTATCGGCCACTACGAGATGCGGTACGAGATTCAGGGTTCCACCCTCTAT
CTGCTACGCCTGTGGCACACACGCGAGGATCGATAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10104.45 Da        Isoelectric Point: 5.7066

>AT72429 WP_095170298.1 NZ_CP019427:3125034-3125306 [Pseudomonas sp. S04]
MVTTAKTRSVTAHVPVQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSL
STESPLPVPR

Download         Length: 273 bp

>AT72429 NZ_CP019427:3125034-3125306 [Pseudomonas sp. S04]
ATGGTTACTACCGCCAAGACCCGATCCGTCACGGCTCATGTCCCTGTGCAACTGGCTGAGAAGGTCGATTTGATGGCTGA
GCGCCTTGAGCGCTCCAAGAACTGGATCGTCAAACAGGCCCTTTCTGCCTGGATTGACCAAGAAGAAGAACGCAGTCGCC
TGACCCGAGAGGCCTTGGCTGATGTGGACGCCGGCCGGGTAATTGACCACCAGGCTGTCCAGGCTTGGGCCGACAGCCTG
AGTACAGAATCCCCGCTGCCAGTGCCGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References