Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 3271720..3272202 Replicon chromosome
Accession NZ_CP019401
Organism Planococcus faecalis strain AJ003

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag AJGP001_RS16205 Protein ID WP_071152809.1
Coordinates 3271939..3272202 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag AJGP001_RS16200 Protein ID WP_071152808.1
Coordinates 3271720..3271932 (+) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AJGP001_RS16170 3267417..3268106 - 690 WP_071152802.1 copper homeostasis protein CutC -
AJGP001_RS16175 3268405..3268785 + 381 WP_071152803.1 VOC family protein -
AJGP001_RS16180 3268998..3269285 + 288 WP_071152804.1 hypothetical protein -
AJGP001_RS16185 3269332..3270294 + 963 WP_071152805.1 DUF3885 domain-containing protein -
AJGP001_RS16190 3270514..3270804 - 291 WP_071152806.1 helix-turn-helix domain-containing protein -
AJGP001_RS16195 3270810..3271262 - 453 WP_071152807.1 hypothetical protein -
AJGP001_RS16200 3271720..3271932 + 213 WP_071152808.1 hypothetical protein Antitoxin
AJGP001_RS16205 3271939..3272202 + 264 WP_071152809.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
AJGP001_RS17415 3272412..3272489 + 78 Protein_3142 AbrB family transcriptional regulator -
AJGP001_RS16210 3272832..3273128 - 297 WP_071152810.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein -
AJGP001_RS16215 3273369..3273761 + 393 WP_071152811.1 disulfide bond formation protein DsbD -
AJGP001_RS16220 3273817..3274017 + 201 WP_071152812.1 hypothetical protein -
AJGP001_RS16225 3274075..3274254 + 180 WP_071152813.1 hypothetical protein -
AJGP001_RS16230 3274273..3274725 + 453 WP_071152814.1 GNAT family N-acetyltransferase -
AJGP001_RS16235 3274754..3275959 - 1206 WP_071152815.1 ABC transporter permease -
AJGP001_RS16240 3275946..3276845 - 900 WP_071152816.1 ATP-binding cassette domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin

Protein of unknown function DUF6290

(1-68)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10341.12 Da        Isoelectric Point: 10.0437

>T72418 WP_071152809.1 NZ_CP019401:3271939-3272202 [Planococcus faecalis]
MYAVHFSDVALKKLKKMDRYQASLLIGWIEKNLKDTDDPRIQGKALVANHKGKWRYRVGDYRILALIEDEKIIITIIDVR
HRKDIYE

Download         Length: 264 bp

>T72418 NZ_CP019401:3271939-3272202 [Planococcus faecalis]
ATGTATGCAGTTCATTTCTCAGATGTCGCGTTGAAGAAATTAAAAAAGATGGACCGGTACCAGGCCTCTCTCCTGATTGG
CTGGATTGAAAAGAACTTGAAGGATACCGACGATCCACGAATACAGGGCAAGGCATTGGTTGCAAACCACAAAGGCAAGT
GGCGTTATCGGGTTGGTGATTACCGTATTCTAGCGTTGATCGAAGACGAAAAGATCATTATTACCATTATCGATGTTAGA
CATCGAAAAGATATCTACGAATAA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8053.16 Da        Isoelectric Point: 4.4734

>AT72418 WP_071152808.1 NZ_CP019401:3271720-3271932 [Planococcus faecalis]
MATISLRVDDRDSKLIRDYAKLKNTSVSDLMRNAIIEKIEDELDVENFDRLLATMETTHSLDDVKKELGL

Download         Length: 213 bp

>AT72418 NZ_CP019401:3271720-3271932 [Planococcus faecalis]
ATGGCCACTATTTCTTTGCGTGTGGATGACCGCGACAGCAAACTCATCCGCGACTACGCCAAACTGAAAAACACATCTGT
TTCGGATTTGATGCGGAATGCCATCATCGAGAAGATTGAAGATGAACTGGATGTCGAAAACTTTGACCGGCTCCTTGCCA
CTATGGAAACAACCCATTCCTTGGATGACGTCAAAAAAGAATTGGGTTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References