Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/PHD(antitoxin) |
| Location | 2176945..2177627 | Replicon | chromosome |
| Accession | NZ_CP019400 | ||
| Organism | Acidipropionibacterium acidipropionici strain WSH1105 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | BWX38_RS09990 | Protein ID | WP_051281999.1 |
| Coordinates | 2176945..2177364 (-) | Length | 140 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | K7SF30 |
| Locus tag | BWX38_RS09995 | Protein ID | WP_015068797.1 |
| Coordinates | 2177364..2177627 (-) | Length | 88 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BWX38_RS09945 | 2171956..2172339 | + | 384 | WP_028701411.1 | D-ribose pyranase | - |
| BWX38_RS09950 | 2172356..2173117 | - | 762 | WP_015068790.1 | ABC transporter permease | - |
| BWX38_RS09955 | 2173114..2173917 | - | 804 | WP_028701410.1 | ATP-binding cassette domain-containing protein | - |
| BWX38_RS09960 | 2173914..2174321 | - | 408 | WP_126133026.1 | DUF1048 domain-containing protein | - |
| BWX38_RS09965 | 2174321..2174638 | - | 318 | WP_198027931.1 | PadR family transcriptional regulator | - |
| BWX38_RS09970 | 2174800..2175717 | - | 918 | WP_081685417.1 | SDR family oxidoreductase | - |
| BWX38_RS09980 | 2176105..2176472 | + | 368 | Protein_1956 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| BWX38_RS09985 | 2176472..2176783 | + | 312 | WP_081685418.1 | helix-turn-helix domain-containing protein | - |
| BWX38_RS09990 | 2176945..2177364 | - | 420 | WP_051281999.1 | type II toxin-antitoxin system VapC family toxin | Toxin |
| BWX38_RS09995 | 2177364..2177627 | - | 264 | WP_015068797.1 | type II toxin-antitoxin system prevent-host-death family antitoxin | Antitoxin |
| BWX38_RS10000 | 2177749..2178015 | - | 267 | WP_015068798.1 | hypothetical protein | - |
| BWX38_RS10005 | 2178245..2178694 | + | 450 | WP_015068799.1 | CBS domain-containing protein | - |
| BWX38_RS10010 | 2178747..2180039 | + | 1293 | WP_028701406.1 | ArsB/NhaD family transporter | - |
| BWX38_RS10015 | 2180103..2180900 | - | 798 | WP_157756374.1 | MFS transporter | - |
| BWX38_RS17035 | 2181624..2181776 | - | 153 | WP_154662074.1 | hypothetical protein | - |
| BWX38_RS10025 | 2181773..2182207 | - | 435 | WP_028701403.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 140 a.a. Molecular weight: 15091.37 Da Isoelectric Point: 4.9147
>T72414 WP_051281999.1 NZ_CP019400:c2177364-2176945 [Acidipropionibacterium acidipropionici]
MFYADTSALVKLVVIEPESGALLDWLGHRDAALATSDLARTELVRSMRRRAPEAITQARDVLSRLLLVRADAQIFDEAAR
LMPPEVRSLDAVHLATALALGDDLEGVITYNLRMADAAHSLGLEVVAPGTPRNPQPNII
MFYADTSALVKLVVIEPESGALLDWLGHRDAALATSDLARTELVRSMRRRAPEAITQARDVLSRLLLVRADAQIFDEAAR
LMPPEVRSLDAVHLATALALGDDLEGVITYNLRMADAAHSLGLEVVAPGTPRNPQPNII
Download Length: 420 bp
>T72414 NZ_CP019400:c2177364-2176945 [Acidipropionibacterium acidipropionici]
ATGTTCTACGCGGACACCTCTGCACTGGTGAAACTCGTCGTCATCGAGCCGGAGTCCGGAGCCCTGCTGGACTGGCTCGG
ACACCGCGACGCCGCCCTGGCGACCAGCGACCTTGCCCGCACCGAGCTGGTGCGCTCCATGCGCCGCAGGGCTCCAGAGG
CCATCACGCAGGCCCGCGACGTGCTGTCACGACTGCTCCTGGTGAGGGCCGATGCCCAGATCTTCGACGAAGCCGCACGT
CTCATGCCGCCAGAGGTTCGAAGTCTCGACGCCGTGCATCTCGCCACTGCACTGGCACTGGGGGACGATCTCGAGGGAGT
CATCACCTACAACCTCCGGATGGCCGACGCCGCCCACAGCCTGGGGCTGGAGGTCGTCGCACCGGGGACACCACGAAACC
CCCAGCCAAACATCATCTGA
ATGTTCTACGCGGACACCTCTGCACTGGTGAAACTCGTCGTCATCGAGCCGGAGTCCGGAGCCCTGCTGGACTGGCTCGG
ACACCGCGACGCCGCCCTGGCGACCAGCGACCTTGCCCGCACCGAGCTGGTGCGCTCCATGCGCCGCAGGGCTCCAGAGG
CCATCACGCAGGCCCGCGACGTGCTGTCACGACTGCTCCTGGTGAGGGCCGATGCCCAGATCTTCGACGAAGCCGCACGT
CTCATGCCGCCAGAGGTTCGAAGTCTCGACGCCGTGCATCTCGCCACTGCACTGGCACTGGGGGACGATCTCGAGGGAGT
CATCACCTACAACCTCCGGATGGCCGACGCCGCCCACAGCCTGGGGCTGGAGGTCGTCGCACCGGGGACACCACGAAACC
CCCAGCCAAACATCATCTGA
Antitoxin
Download Length: 88 a.a. Molecular weight: 9390.67 Da Isoelectric Point: 10.3568
>AT72414 WP_015068797.1 NZ_CP019400:c2177627-2177364 [Acidipropionibacterium acidipropionici]
MSEVGIRELKQNASSVVRRAAAGEEITVTDRGRPVARLSAIDHGGVRGLLAADRARPPIRALSDLPAPTIAADVSSVLRQ
MRDEERY
MSEVGIRELKQNASSVVRRAAAGEEITVTDRGRPVARLSAIDHGGVRGLLAADRARPPIRALSDLPAPTIAADVSSVLRQ
MRDEERY
Download Length: 264 bp
>AT72414 NZ_CP019400:c2177627-2177364 [Acidipropionibacterium acidipropionici]
ATGAGTGAGGTCGGCATCCGCGAGTTGAAGCAGAACGCCTCGAGCGTCGTCCGCCGGGCCGCCGCTGGCGAGGAGATCAC
GGTGACCGATCGGGGTCGTCCGGTCGCGCGACTCTCCGCCATCGATCACGGCGGAGTGCGCGGGCTGCTCGCCGCCGACC
GGGCCCGCCCACCGATCCGGGCACTGAGCGATCTCCCCGCGCCCACGATCGCCGCCGACGTCTCCTCGGTTCTCCGGCAG
ATGCGCGACGAGGAGCGCTACTGA
ATGAGTGAGGTCGGCATCCGCGAGTTGAAGCAGAACGCCTCGAGCGTCGTCCGCCGGGCCGCCGCTGGCGAGGAGATCAC
GGTGACCGATCGGGGTCGTCCGGTCGCGCGACTCTCCGCCATCGATCACGGCGGAGTGCGCGGGCTGCTCGCCGCCGACC
GGGCCCGCCCACCGATCCGGGCACTGAGCGATCTCCCCGCGCCCACGATCGCCGCCGACGTCTCCTCGGTTCTCCGGCAG
ATGCGCGACGAGGAGCGCTACTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|