Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/COG3657-dnstrm_HI1420
Location 6392518..6393107 Replicon chromosome
Accession NZ_CP019399
Organism Pseudomonas chlororaphis strain R47

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PchlR47_RS28600 Protein ID WP_053270039.1
Coordinates 6392808..6393107 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag PchlR47_RS28595 Protein ID WP_028683469.1
Coordinates 6392518..6392811 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PchlR47_RS28575 6388059..6389222 - 1164 WP_124302191.1 acyltransferase -
PchlR47_RS28580 6389417..6390607 - 1191 WP_028683472.1 serine hydrolase -
PchlR47_RS28585 6390734..6391621 + 888 WP_009051074.1 LysR family transcriptional regulator -
PchlR47_RS28590 6391993..6392385 + 393 WP_009051075.1 hypothetical protein -
PchlR47_RS28595 6392518..6392811 - 294 WP_028683469.1 putative addiction module antidote protein Antitoxin
PchlR47_RS28600 6392808..6393107 - 300 WP_053270039.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PchlR47_RS28605 6393278..6393727 + 450 WP_124302193.1 DUF3828 domain-containing protein -
PchlR47_RS28610 6393752..6394762 - 1011 WP_173424526.1 NAD(P)-dependent alcohol dehydrogenase -
PchlR47_RS28615 6394820..6395119 - 300 WP_009051080.1 ArsR family transcriptional regulator -
PchlR47_RS28620 6395183..6396274 - 1092 WP_009051081.1 nitrite reductase, copper-containing -
PchlR47_RS28625 6396500..6396742 + 243 WP_007924102.1 exodeoxyribonuclease VII small subunit -
PchlR47_RS28630 6396739..6397626 + 888 WP_124302194.1 (2E,6E)-farnesyl diphosphate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-96)

Antitoxin

Uncharacterized protein HI1420

(11-92)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11267.01 Da        Isoelectric Point: 10.4277

>T72411 WP_053270039.1 NZ_CP019399:c6393107-6392808 [Pseudomonas chlororaphis]
MIEIKQTATFMEWENRLKDSRARALIAARIFRLANGLAGDVPPVGEGVSELRIHYGPGYRVYFQQLGSQLVILLCGGDKS
RQSRDIELAKYLARRWSRS

Download         Length: 300 bp

>T72411 NZ_CP019399:c6393107-6392808 [Pseudomonas chlororaphis]
ATGATCGAGATCAAACAGACCGCGACCTTTATGGAGTGGGAAAACAGGCTCAAGGATTCCAGAGCCAGGGCGTTGATCGC
TGCGCGGATTTTTCGCCTGGCCAATGGCCTTGCCGGTGACGTGCCACCGGTGGGCGAGGGCGTCAGCGAGTTGCGCATCC
ATTACGGGCCGGGCTACCGAGTTTATTTCCAGCAGCTTGGTTCGCAACTTGTCATTTTGTTATGCGGCGGCGACAAGAGT
CGCCAGAGCCGCGATATCGAACTGGCCAAATACCTGGCCCGTCGTTGGAGCCGATCATGA

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10444.96 Da        Isoelectric Point: 5.6642

>AT72411 WP_028683469.1 NZ_CP019399:c6392811-6392518 [Pseudomonas chlororaphis]
MNEPLFDYDPATALRDPQAIALFMADAFETGDAGYIAKALGVVARAKGMTELAHETGLSREQLYRSFSDKGNPTLKTLLA
VMRALGLEMTARVHGAS

Download         Length: 294 bp

>AT72411 NZ_CP019399:c6392811-6392518 [Pseudomonas chlororaphis]
ATGAACGAACCGCTTTTCGACTATGACCCCGCCACGGCCTTGCGCGACCCGCAAGCCATTGCCCTGTTCATGGCGGACGC
CTTCGAGACCGGCGATGCCGGCTACATCGCCAAAGCCCTGGGCGTGGTGGCGCGGGCCAAGGGCATGACCGAACTGGCCC
ATGAAACCGGGCTGTCCCGCGAGCAGCTGTACCGCTCGTTCAGTGACAAGGGCAACCCGACCCTGAAGACCCTGCTGGCG
GTGATGCGCGCCCTGGGGCTGGAGATGACGGCGCGGGTGCATGGGGCGTCTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References