Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbE-relB/ParE-YafN
Location 201918..202434 Replicon chromosome
Accession NZ_CP019399
Organism Pseudomonas chlororaphis strain R47

Toxin (Protein)


Gene name stbE Uniprot ID A0A8A9Z863
Locus tag PchlR47_RS00865 Protein ID WP_028681510.1
Coordinates 202153..202434 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A554PKE4
Locus tag PchlR47_RS00860 Protein ID WP_009046356.1
Coordinates 201918..202163 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PchlR47_RS00835 197686..198681 + 996 WP_124312600.1 sulfotransferase family protein -
PchlR47_RS00840 198647..199405 - 759 WP_009046352.1 slipin family protein -
PchlR47_RS00845 199407..200792 - 1386 WP_009046353.1 nodulation protein NfeD -
PchlR47_RS00850 201016..201477 + 462 WP_016705004.1 YbaK/EbsC family protein -
PchlR47_RS00855 201608..201853 + 246 WP_009046355.1 DUF2789 domain-containing protein -
PchlR47_RS00860 201918..202163 + 246 WP_009046356.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PchlR47_RS00865 202153..202434 + 282 WP_028681510.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PchlR47_RS00870 202567..202995 + 429 WP_028681511.1 winged helix DNA-binding protein -
PchlR47_RS00875 202992..205076 + 2085 WP_101281622.1 FUSC family protein -
PchlR47_RS00880 205073..205282 + 210 WP_007932080.1 DUF1656 domain-containing protein -
PchlR47_RS00885 205279..206175 + 897 WP_038630331.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-70)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10907.82 Da        Isoelectric Point: 10.6258

>T72404 WP_028681510.1 NZ_CP019399:202153-202434 [Pseudomonas chlororaphis]
MTYKLQFLPSARKEWDKLGHTLREQFKRKLAERLEMPRVPADALHGMADCYKIKLKASGYRLVYQVIEDQVVVSVVAVGK
RERSAVYERARKR

Download         Length: 282 bp

>T72404 NZ_CP019399:202153-202434 [Pseudomonas chlororaphis]
ATGACTTATAAGCTCCAGTTCCTGCCTTCGGCGCGCAAGGAATGGGACAAGCTCGGTCATACCCTGCGCGAGCAATTCAA
GAGGAAGCTGGCCGAGCGCCTGGAAATGCCGCGGGTGCCCGCGGACGCCCTTCACGGTATGGCGGACTGCTACAAGATCA
AGCTCAAGGCCTCTGGCTATCGCCTGGTTTACCAAGTGATCGAGGATCAGGTCGTGGTTTCGGTGGTGGCCGTGGGCAAA
CGTGAACGCAGTGCCGTGTATGAGCGGGCCCGAAAGCGCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8814.14 Da        Isoelectric Point: 4.7164

>AT72404 WP_009046356.1 NZ_CP019399:201918-202163 [Pseudomonas chlororaphis]
MQSVLADKAVSVSELKKNPSAVLNGAQGGAVAVLNHNRVMGYMVPADVFEAMMERLDDLELAEIVRARRHETPVPVNLDD
L

Download         Length: 246 bp

>AT72404 NZ_CP019399:201918-202163 [Pseudomonas chlororaphis]
ATGCAAAGCGTATTGGCTGATAAAGCTGTCAGCGTGTCTGAACTGAAAAAAAATCCTTCGGCTGTCCTGAACGGCGCACA
GGGTGGTGCGGTTGCGGTGCTCAATCACAACCGGGTCATGGGCTATATGGTCCCGGCCGACGTGTTTGAAGCCATGATGG
AGCGTCTTGACGATCTTGAACTGGCGGAGATTGTCCGTGCCCGTCGTCACGAGACCCCGGTCCCGGTAAATCTGGATGAC
TTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A8A9Z863

Antitoxin

Source ID Structure
AlphaFold DB A0A554PKE4

References