Detailed information of TA system TA072403

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 4361186..4361636
• Replicon: chromosome
• Accession: NZ_CP019398
• Organism: Pseudomonas sp. S34

Toxin (Protein)

• Gene name: relE
• Uniprot ID: A0A6I6VLX1
• Locus tag: PspS34_RS19415
• Protein ID: WP_046043167.1
• Coordinates: 4361186..4361455 (-)
• Length: 90 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: PspS34_RS19420
• Protein ID: WP_154861482.1
• Coordinates: 4361445..4361636 (-)
• Length: 64 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PspS34_RS19390	4358364..4358879	-	516	WP_154947191.1	PaaI family thioesterase	-
PspS34_RS19395	4358946..4359482	-	537	WP_154947190.1	VOC family protein	-
PspS34_RS19400	4359689..4360141	-	453	WP_154947189.1	hypothetical protein	-
PspS34_RS19405	4360161..4360616	-	456	WP_154947203.1	GNAT family N-acetyltransferase	-
PspS34_RS19410	4360667..4361074	-	408	WP_159390279.1	VOC family protein	-
PspS34_RS19415	4361186..4361455	-	270	WP_046043167.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PspS34_RS19420	4361445..4361636	-	192	WP_154861482.1	antitoxin	Antitoxin
PspS34_RS19425	4362203..4362562	+	360	WP_154947187.1	hypothetical protein	-
PspS34_RS19430	4362713..4363678	-	966	WP_154947185.1	alpha/beta hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-88)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 90 a.a.
• Molecular weight: 10425.95 Da
• Isoelectric Point: 6.2181

>T72403 WP_046043167.1 NZ_CP019398:c4361455-4361186 [Pseudomonas sp. S34]
MLVEWRPEARAELWQILNYIGDRNFVAASELFQAIEAATSALPEHPYLYRFGRVPGTREIVVHPNYLVVYRVTDRIEILS
VLHARQEYP

Nucleotide

• Length: 270 bp

>T72403 NZ_CP019398:c4361455-4361186 [Pseudomonas sp. S34]
ATGCTGGTTGAGTGGCGGCCCGAAGCACGGGCCGAACTCTGGCAAATCCTGAATTACATTGGCGACCGAAACTTCGTAGC
GGCCAGCGAGCTATTTCAAGCCATTGAAGCTGCTACATCGGCCCTTCCCGAACATCCCTACCTTTATCGATTCGGTCGAG
TGCCCGGCACTCGGGAGATTGTCGTGCATCCCAACTACCTGGTGGTTTACCGAGTGACGGATCGAATCGAGATATTGAGC
GTGTTGCATGCTCGGCAGGAATATCCCTGA

Antitoxin

Protein

• Length: 64 a.a.
• Molecular weight: 7172.01 Da
• Isoelectric Point: 5.6401

>AT72403 WP_154861482.1 NZ_CP019398:c4361636-4361445 [Pseudomonas sp. S34]
MSAELSPIVSEFETKEQAASYDRWFRAKVQASLDDPRPNVPHDQVMADMRALIESKRNKHDAG

Nucleotide

• Length: 192 bp

>AT72403 NZ_CP019398:c4361636-4361445 [Pseudomonas sp. S34]
ATGAGCGCCGAACTTTCCCCTATCGTTTCAGAGTTTGAGACCAAAGAGCAGGCCGCCAGCTATGACCGTTGGTTCCGCGC
CAAGGTCCAAGCTTCGCTTGACGACCCACGCCCGAATGTCCCGCACGATCAGGTGATGGCCGATATGCGAGCCCTCATCG
AATCAAAGCGCAACAAACACGATGCTGGTTGA

Structures

Toxin

• AlphaFold DB: A0A6I6VLX1