Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 1464627..1465140 Replicon chromosome
Accession NZ_CP019398
Organism Pseudomonas sp. S34

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PspS34_RS06375 Protein ID WP_154861764.1
Coordinates 1464627..1464911 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PspS34_RS06380 Protein ID WP_154861762.1
Coordinates 1464901..1465140 (-) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PspS34_RS06355 1460583..1461509 + 927 WP_154861772.1 hydroxymethylglutaryl-CoA lyase -
PspS34_RS06360 1461683..1463014 + 1332 WP_154861768.1 MFS transporter -
PspS34_RS06365 1463133..1463621 - 489 WP_150814264.1 DMT family transporter -
PspS34_RS06370 1463699..1464607 + 909 WP_154861766.1 LysR family transcriptional regulator -
PspS34_RS06375 1464627..1464911 - 285 WP_154861764.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PspS34_RS06380 1464901..1465140 - 240 WP_154861762.1 ribbon-helix-helix protein, CopG family Antitoxin
PspS34_RS06385 1465294..1465932 + 639 WP_150814266.1 LysE family translocator -
PspS34_RS06390 1466012..1467358 + 1347 WP_154861760.1 GGDEF domain-containing protein -
PspS34_RS06395 1467477..1467635 + 159 WP_007976786.1 stress protein -
PspS34_RS06400 1467708..1468211 + 504 WP_154861758.1 DUF4142 domain-containing protein -
PspS34_RS06405 1468267..1468677 - 411 WP_090453624.1 low affinity iron permease family protein -
PspS34_RS06410 1468890..1469975 + 1086 WP_102672066.1 type I restriction enzyme HsdR N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-89)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-41)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10918.63 Da        Isoelectric Point: 10.8916

>T72402 WP_154861764.1 NZ_CP019398:c1464911-1464627 [Pseudomonas sp. S34]
MRVEWLRTALKNLDDEAAYIAIENPKAAADFVQAILASVDHLARFPATGREGRLPGTREWVIPDRPYLIPYRVRQGRLQV
LRIFHTRRLPPSNW

Download         Length: 285 bp

>T72402 NZ_CP019398:c1464911-1464627 [Pseudomonas sp. S34]
ATGCGCGTTGAGTGGTTGCGTACGGCGTTAAAGAATCTGGATGACGAAGCCGCGTACATTGCCATCGAGAATCCAAAAGC
TGCAGCAGATTTTGTCCAGGCAATTCTCGCCAGTGTCGATCACCTTGCCCGATTTCCAGCGACGGGCCGTGAAGGACGCC
TACCCGGTACCCGGGAATGGGTCATTCCTGATCGCCCCTATTTGATTCCCTACCGGGTTCGCCAAGGTCGGCTTCAGGTA
CTACGGATTTTTCATACGCGTCGCCTGCCACCTTCCAATTGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8757.80 Da        Isoelectric Point: 4.3193

>AT72402 WP_154861762.1 NZ_CP019398:c1465140-1464901 [Pseudomonas sp. S34]
MSVMSLRIPDEIADTLASLSKATGRSKSFLAVDALREYLAREAWQIEEIQKALKEADDGDFATQEDVNAIADKWTANAR

Download         Length: 240 bp

>AT72402 NZ_CP019398:c1465140-1464901 [Pseudomonas sp. S34]
ATGTCAGTTATGTCCCTGCGCATACCAGACGAAATCGCCGATACTCTCGCGAGTCTTTCCAAAGCAACGGGCCGCAGCAA
ATCATTTCTGGCCGTGGATGCGCTGCGTGAGTACCTGGCCCGTGAAGCGTGGCAAATCGAGGAAATTCAGAAAGCCTTGA
AAGAAGCCGATGACGGTGACTTCGCGACACAAGAAGACGTGAACGCAATTGCAGACAAGTGGACGGCGAATGCGCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References