Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 670919..671515 Replicon chromosome
Accession NZ_CP019398
Organism Pseudomonas sp. S34

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PspS34_RS02890 Protein ID WP_150813566.1
Coordinates 671213..671515 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A6I6VCV4
Locus tag PspS34_RS02885 Protein ID WP_057397803.1
Coordinates 670919..671209 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PspS34_RS02865 667121..669238 - 2118 WP_154861091.1 TonB-dependent copper receptor -
PspS34_RS02870 669431..669874 - 444 WP_150813569.1 DUF2946 domain-containing protein -
PspS34_RS02875 669896..670375 - 480 WP_150813568.1 copper chaperone PCu(A)C -
PspS34_RS02880 670423..670821 - 399 WP_150813567.1 DUF2946 domain-containing protein -
PspS34_RS02885 670919..671209 - 291 WP_057397803.1 putative addiction module antidote protein Antitoxin
PspS34_RS02890 671213..671515 - 303 WP_150813566.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PspS34_RS02895 671717..672433 - 717 WP_150813565.1 cobalt-precorrin-6A reductase -
PspS34_RS02900 672430..673527 - 1098 WP_154861090.1 cobalt-precorrin-5B (C(1))-methyltransferase -
PspS34_RS02905 673520..674731 - 1212 WP_154861089.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
PspS34_RS02910 674870..675517 - 648 WP_154861088.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Uncharacterized protein HI1420

(4-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11560.18 Da        Isoelectric Point: 8.8458

>T72401 WP_150813566.1 NZ_CP019398:c671515-671213 [Pseudomonas sp. S34]
MVEFERSRVFADWLNSLRDTIGKARIIARLRAAEYGNFGDCESVGAAVYEMRVHYGPGYRLYFTRRDEVIYLLLIGGDKS
TQKRDIKRAIQMAHNIGNEE

Download         Length: 303 bp

>T72401 NZ_CP019398:c671515-671213 [Pseudomonas sp. S34]
ATGGTCGAATTTGAGCGATCCCGAGTATTTGCTGACTGGCTCAACTCGCTGAGGGACACCATTGGCAAAGCTCGAATAAT
CGCGAGACTCCGGGCAGCCGAGTATGGAAATTTTGGTGATTGTGAATCTGTAGGTGCTGCGGTGTATGAGATGCGCGTTC
ACTACGGCCCAGGCTACAGGTTGTACTTCACTCGCAGAGATGAGGTGATTTACTTGCTGTTGATCGGGGGTGACAAGTCG
ACTCAAAAACGAGATATCAAACGTGCTATTCAAATGGCACACAATATCGGTAATGAGGAGTAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10382.95 Da        Isoelectric Point: 4.8096

>AT72401 WP_057397803.1 NZ_CP019398:c671209-670919 [Pseudomonas sp. S34]
MAEQFTRFDAAEFLKTPEEMAAYLDACFEEDAGDGVLIRAALNDIARAKGMTQIARDAGLGRESLYKALSSSGNPEFATI
MKVMKALGLRLHAIAV

Download         Length: 291 bp

>AT72401 NZ_CP019398:c671209-670919 [Pseudomonas sp. S34]
ATGGCCGAACAATTTACCCGTTTTGATGCCGCCGAGTTTCTCAAGACACCGGAAGAAATGGCGGCTTATCTGGATGCCTG
CTTTGAAGAGGATGCTGGAGACGGCGTGCTGATACGTGCAGCGCTCAACGATATCGCCCGGGCAAAGGGCATGACACAAA
TAGCCCGTGATGCCGGCTTGGGGCGCGAGAGTCTGTACAAGGCACTGAGCAGTAGTGGCAATCCGGAATTCGCGACTATC
ATGAAGGTTATGAAAGCCTTGGGTCTGCGTTTGCACGCCATCGCTGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A6I6VCV4

References