Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 450258..450847 Replicon chromosome
Accession NZ_CP019398
Organism Pseudomonas sp. S34

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag PspS34_RS01970 Protein ID WP_090452714.1
Coordinates 450258..450563 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PspS34_RS01975 Protein ID WP_007943750.1
Coordinates 450560..450847 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PspS34_RS01945 445491..446342 + 852 WP_150811949.1 general secretion pathway protein GspK -
PspS34_RS01950 446339..447445 + 1107 WP_154861176.1 type II secretory protein pull -
PspS34_RS01955 447442..447873 + 432 WP_154861175.1 type II secretion system protein M -
PspS34_RS01960 447866..449146 - 1281 WP_154861174.1 MFS transporter -
PspS34_RS01965 449265..450167 + 903 WP_154861173.1 LysR family transcriptional regulator -
PspS34_RS01970 450258..450563 + 306 WP_090452714.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PspS34_RS01975 450560..450847 + 288 WP_007943750.1 putative addiction module antidote protein Antitoxin
PspS34_RS01980 451466..451729 + 264 WP_154861172.1 hypothetical protein -
PspS34_RS01985 451851..453077 - 1227 WP_154861171.1 beta-ketoacyl-ACP synthase -
PspS34_RS01990 453077..453805 - 729 WP_154861170.1 3-oxoacyl-ACP reductase FabG -
PspS34_RS01995 453805..454263 - 459 WP_154861169.1 hotdog family protein -
PspS34_RS02000 454260..455456 - 1197 WP_154861168.1 beta-ketoacyl-[acyl-carrier-protein] synthase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-95)

Antitoxin

Uncharacterized protein HI1420

(3-95)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11407.09 Da        Isoelectric Point: 9.9969

>T72400 WP_090452714.1 NZ_CP019398:450258-450563 [Pseudomonas sp. S34]
MTEILRSSTFSGWLLKLADSRARMRIQVRIDRMADGNFGDVKAIGEGLSEARIDYGPGYRIYFMQQGSQLVILLCGGDKS
SQPRDIKQARLIAKSWQEQNP

Download         Length: 306 bp

>T72400 NZ_CP019398:450258-450563 [Pseudomonas sp. S34]
ATGACGGAGATCCTTCGAAGTTCAACATTCTCTGGCTGGCTGTTAAAGCTGGCCGATAGTCGCGCCAGGATGCGTATTCA
GGTGCGAATTGACCGCATGGCCGATGGGAATTTCGGTGATGTCAAAGCCATCGGAGAAGGGTTGAGTGAAGCACGTATCG
ACTATGGTCCCGGTTATCGGATCTATTTCATGCAGCAAGGCAGCCAGTTGGTCATCCTCCTTTGTGGCGGAGACAAAAGC
AGCCAACCCCGTGACATCAAACAAGCCAGGCTCATTGCGAAATCCTGGCAGGAGCAAAACCCATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10372.72 Da        Isoelectric Point: 4.6412

>AT72400 WP_007943750.1 NZ_CP019398:450560-450847 [Pseudomonas sp. S34]
MTEQFTRWDSAEYLKTEEDMANYLDACMEEAGDDPAFIAKALGTIARARGMTQVARDAGLSRESLYRALSGEGNPEFGTI
LKVVKALGLKLHAST

Download         Length: 288 bp

>AT72400 NZ_CP019398:450560-450847 [Pseudomonas sp. S34]
ATGACCGAACAATTCACTCGCTGGGACTCTGCCGAGTACCTCAAGACCGAAGAGGACATGGCTAATTACCTGGATGCTTG
CATGGAAGAGGCGGGAGATGACCCTGCGTTCATCGCCAAAGCACTAGGGACTATTGCACGTGCTCGCGGCATGACTCAGG
TCGCACGGGATGCGGGGCTTTCTCGGGAAAGTCTTTATCGTGCATTGTCAGGTGAGGGGAATCCGGAGTTCGGCACCATC
CTGAAAGTCGTTAAGGCATTGGGCTTGAAATTACACGCCAGCACCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References