Detailed information of TA system TA072399

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 5572939..5573455
• Replicon: chromosome
• Accession: NZ_CP019397
• Organism: Pseudomonas sp. S19

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PspS19_RS25005
• Protein ID: WP_159998235.1
• Coordinates: 5572939..5573226 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: PspS19_RS25010
• Protein ID: WP_159998237.1
• Coordinates: 5573216..5573455 (-)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PspS19_RS24995	5568478..5572221	+	3744	WP_159998233.1	bifunctional diguanylate cyclase/phosphodiesterase	-
PspS19_RS25005	5572939..5573226	-	288	WP_159998235.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
PspS19_RS25010	5573216..5573455	-	240	WP_159998237.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
PspS19_RS25015	5573776..5574030	-	255	Protein_4904	HipA N-terminal domain-containing protein	-
PspS19_RS25020	5574030..5574227	-	198	WP_159998926.1	transcriptional regulator	-
PspS19_RS25025	5574497..5575291	+	795	WP_095170607.1	lipopolysaccharide biosynthesis protein	-
PspS19_RS25030	5575382..5575843	+	462	WP_095170609.1	Lrp/AsnC family transcriptional regulator	-
PspS19_RS25035	5575984..5577666	+	1683	WP_095170611.1	NAD(P)/FAD-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-83)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (1-79)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11263.19 Da
• Isoelectric Point: 10.2588

>T72399 WP_159998235.1 NZ_CP019397:c5573226-5572939 [Pseudomonas sp. S19]
MTYSLEFDARALKEWHKLGDTVRQQLKKKLATILVNPRIEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVMVFVVAVDK
REREQVYRKAVERLS

Nucleotide

• Length: 288 bp

>T72399 NZ_CP019397:c5573226-5572939 [Pseudomonas sp. S19]
ATGACCTATAGCCTTGAGTTCGATGCGCGGGCGTTAAAGGAGTGGCACAAACTGGGGGATACCGTTCGCCAGCAACTCAA
GAAGAAACTGGCTACGATCCTGGTCAATCCGCGTATTGAAGCCAACCGTCTGCATGCGTTGCCCGACTGCTACAAGATCA
AGTTGCGTAGCAGCGGCTATCGGCTGGTTTATCAAGTGATCGACCAAGAGGTCATGGTGTTTGTGGTGGCCGTTGATAAG
CGCGAGCGTGAGCAGGTTTATCGTAAAGCGGTTGAGCGGTTGAGCTAG

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 8949.32 Da
• Isoelectric Point: 4.7962

>AT72399 WP_159998237.1 NZ_CP019397:c5573455-5573216 [Pseudomonas sp. S19]
MASINVRIDDDLKARAYHELEKLGVTPSELMRQALQYVAERGQLPFKPVLMTEDDEALIATVRERLAAPQRVKVSLDDL

Nucleotide

• Length: 240 bp

>AT72399 NZ_CP019397:c5573455-5573216 [Pseudomonas sp. S19]
ATGGCATCCATCAATGTCCGTATCGACGACGACCTCAAGGCGCGTGCTTACCACGAGCTGGAAAAACTCGGCGTCACCCC
GTCTGAGTTGATGCGCCAAGCCTTGCAGTACGTGGCAGAGCGCGGTCAGCTACCCTTCAAGCCCGTCCTGATGACCGAGG
ACGATGAAGCCTTGATCGCTACGGTGCGCGAGCGACTGGCTGCTCCCCAGCGGGTTAAGGTTTCACTAGATGACCTATAG