Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2017011..2017282 Replicon chromosome
Accession NZ_CP019361
Organism Escherichia coli strain XH993

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2017141..2017244 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2017011..2017282 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BW158_RS11570 2013567..2014229 - 663 WP_000944256.1 exodeoxyribonuclease X -
BW158_RS11575 2014253..2014909 - 657 WP_000011657.1 carbon-nitrogen hydrolase family protein -
BW158_RS11580 2015011..2015241 - 231 WP_000916763.1 DNA polymerase III subunit theta -
BW158_RS11585 2015380..2015754 + 375 WP_000168747.1 CopC domain-containing protein YobA -
BW158_RS11590 2015758..2016630 + 873 WP_000879294.1 copper homeostasis membrane protein CopD -
BW158_RS11595 2016643..2016984 + 342 WP_000976472.1 YebY family protein -
- 2017011..2017282 - 272 - - Antitoxin
- 2017141..2017244 + 104 - - Toxin
BW158_RS11600 2017379..2018035 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
BW158_RS11605 2018036..2018227 - 192 WP_001296140.1 YebW family protein -
BW158_RS11610 2018332..2018568 - 237 WP_001295499.1 DUF1480 family protein -
BW158_RS11615 2018686..2020125 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T72335 NZ_CP019361:2017141-2017244 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT72335 NZ_CP019361:c2017282-2017011 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References