Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 4075632..4076237 Replicon chromosome
Accession NZ_CP019343
Organism Oceanicoccus sagamiensis strain NBRC 107125

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag BST96_RS20800 Protein ID WP_206045364.1
Coordinates 4076016..4076237 (+) Length 74 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag BST96_RS18515 Protein ID WP_085760115.1
Coordinates 4075632..4075994 (+) Length 121 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BST96_RS18485 4070736..4071179 + 444 WP_085760110.1 cytochrome c -
BST96_RS18490 4071166..4071819 - 654 WP_085760111.1 cytochrome b/b6 domain-containing protein -
BST96_RS18495 4071831..4072442 - 612 WP_085760112.1 tRNA-(ms[2]io[6]A)-hydroxylase -
BST96_RS18500 4072442..4072981 - 540 WP_169714040.1 hypothetical protein -
BST96_RS18505 4072987..4074843 - 1857 WP_085760114.1 hypothetical protein -
BST96_RS18510 4074844..4075338 - 495 WP_085760597.1 DUF1289 domain-containing protein -
BST96_RS18515 4075632..4075994 + 363 WP_085760115.1 MbcA/ParS/Xre antitoxin family protein Antitoxin
BST96_RS20800 4076016..4076237 + 222 WP_206045364.1 hypothetical protein Toxin
BST96_RS18520 4076225..4076764 + 540 Protein_3660 RES family NAD+ phosphorylase -
BST96_RS18525 4076963..4079764 + 2802 WP_085760116.1 bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(71-118)


Sequences

Toxin        


Download         Length: 74 a.a.        Molecular weight: 8607.79 Da        Isoelectric Point: 6.3209

>T72263 WP_206045364.1 NZ_CP019343:4076016-4076237 [Oceanicoccus sagamiensis]
MDIWQACKDRFTLRELNGRLVRVVESQEQVATNHLVDTLEEQHLLEQMLEENKPGHSHKGLHYLLATPFRYPP

Download         Length: 222 bp

>T72263 NZ_CP019343:4076016-4076237 [Oceanicoccus sagamiensis]
ATGGACATTTGGCAAGCCTGTAAGGACCGTTTTACCCTTCGTGAGCTCAACGGTCGATTAGTTCGCGTTGTCGAAAGCCA
GGAGCAGGTTGCCACCAATCATTTGGTCGACACGCTGGAAGAACAACACTTACTGGAGCAAATGCTGGAAGAGAACAAGC
CCGGCCATAGCCATAAGGGCCTGCATTACCTGCTTGCTACCCCCTTCCGTTACCCCCCTTAA

Antitoxin


Download         Length: 121 a.a.        Molecular weight: 13405.54 Da        Isoelectric Point: 9.8429

>AT72263 WP_085760115.1 NZ_CP019343:4075632-4075994 [Oceanicoccus sagamiensis]
MSAAEQRYDQPDPQRVLLKALLNAGKNLGLSKADIGKVIGKDRTSLNRGIAPSSKSGELALFLIRCYRALYVLVGGKPED
IKHWMNTYNHHIQAVPTEEIYTIQGLTRVLEYLDAIRGKI

Download         Length: 363 bp

>AT72263 NZ_CP019343:4075632-4075994 [Oceanicoccus sagamiensis]
ATGAGTGCTGCCGAGCAACGCTATGATCAACCTGATCCACAACGGGTATTACTGAAAGCCTTACTCAATGCCGGTAAAAA
TCTGGGGCTGTCAAAGGCTGATATCGGCAAAGTGATCGGCAAAGATCGCACCTCGCTTAATCGGGGTATCGCGCCCTCAA
GCAAATCCGGGGAATTAGCCCTCTTCTTGATTCGTTGCTACCGGGCTCTCTATGTTCTGGTGGGAGGAAAACCTGAGGAT
ATCAAGCACTGGATGAATACCTACAACCATCATATTCAAGCAGTTCCAACTGAAGAAATATACACTATTCAAGGACTTAC
CAGGGTACTTGAATATCTGGATGCGATTCGTGGAAAAATATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References