Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 3664560..3665028 Replicon chromosome
Accession NZ_CP019343
Organism Oceanicoccus sagamiensis strain NBRC 107125

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag BST96_RS16610 Protein ID WP_085759771.1
Coordinates 3664560..3664832 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag BST96_RS16615 Protein ID WP_085760573.1
Coordinates 3664816..3665028 (-) Length 71 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BST96_RS16580 3659567..3660784 + 1218 WP_085759765.1 NADH:ubiquinone reductase (Na(+)-transporting) subunit F -
BST96_RS16585 3660793..3661833 + 1041 WP_085759766.1 FAD:protein FMN transferase -
BST96_RS16590 3661963..3662205 + 243 WP_085759767.1 (Na+)-NQR maturation NqrM -
BST96_RS16595 3662252..3663379 - 1128 WP_085759768.1 VPLPA-CTERM sorting domain-containing protein -
BST96_RS16600 3663617..3664324 + 708 WP_157117997.1 hypothetical protein -
BST96_RS16605 3664306..3664554 + 249 WP_085759770.1 LytTR family transcriptional regulator -
BST96_RS16610 3664560..3664832 - 273 WP_085759771.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
BST96_RS16615 3664816..3665028 - 213 WP_085760573.1 TraY domain-containing protein Antitoxin
BST96_RS16620 3665334..3665801 - 468 WP_085759772.1 NfeD family protein -
BST96_RS16625 3665812..3666789 - 978 WP_085759773.1 paraslipin -
BST96_RS16630 3666897..3668765 - 1869 WP_085759774.1 type II secretion system secretin GspD -
BST96_RS16635 3668800..3669495 - 696 WP_085759775.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Relaxosome protein TraY

(4-41)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10992.75 Da        Isoelectric Point: 11.1907

>T72262 WP_085759771.1 NZ_CP019343:c3664832-3664560 [Oceanicoccus sagamiensis]
MTWTVEFDDNAAKELRKLDRQAQQEILRYFRQRIATPEDPRRFGKPLSRDLTGLWRYRVRSYRMICHIEDSKLLVLVLRA
GHRRRIYKTS

Download         Length: 273 bp

>T72262 NZ_CP019343:c3664832-3664560 [Oceanicoccus sagamiensis]
TTGACATGGACCGTTGAATTCGACGATAACGCTGCAAAGGAATTGCGCAAACTGGACCGACAAGCTCAACAAGAGATTCT
ACGCTACTTCCGACAACGTATTGCCACTCCTGAAGACCCCCGCCGCTTTGGTAAACCACTCTCCCGTGATTTAACGGGGC
TGTGGCGCTACCGGGTTCGCAGCTACCGTATGATTTGCCATATCGAAGACAGTAAGCTCTTGGTTTTGGTATTACGTGCA
GGGCATCGCAGGCGTATTTATAAGACGAGTTAA

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 8409.57 Da        Isoelectric Point: 4.6583

>AT72262 WP_085760573.1 NZ_CP019343:c3665028-3664816 [Oceanicoccus sagamiensis]
MLAIRLPNEIEDRLNNLASKTGRTKTFYAREAILKYLDEMEDRYLAIDRLEKSGKRWTLDEMEQDIDMDR

Download         Length: 213 bp

>AT72262 NZ_CP019343:c3665028-3664816 [Oceanicoccus sagamiensis]
ATGCTTGCCATTAGACTCCCTAACGAGATTGAAGACCGACTCAATAATCTGGCCTCAAAAACCGGGCGTACCAAGACGTT
TTATGCCCGTGAAGCCATCCTTAAGTATTTAGATGAAATGGAAGATAGATATCTGGCTATCGACCGATTAGAAAAATCCG
GCAAGCGCTGGACTCTCGACGAAATGGAGCAGGATATTGACATGGACCGTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References