Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 3710675..3711065 Replicon chromosome
Accession NZ_CP019326
Organism Halomonas sp. 1513

Toxin (Protein)


Gene name EcnB Uniprot ID -
Locus tag BWR19_RS16930 Protein ID WP_076749415.1
Coordinates 3710675..3710806 (-) Length 44 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID -
Locus tag BWR19_RS16935 Protein ID WP_076750168.1
Coordinates 3710934..3711065 (-) Length 44 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BWR19_RS16905 3706593..3707120 + 528 WP_076749408.1 acyl-CoA thioesterase -
BWR19_RS16910 3707155..3708150 + 996 WP_076749409.1 ion transporter -
BWR19_RS16915 3708162..3709550 - 1389 WP_076749411.1 PLP-dependent aminotransferase family protein -
BWR19_RS16920 3709646..3710251 + 606 WP_076749412.1 LysE family translocator -
BWR19_RS16925 3710256..3710582 - 327 WP_076749414.1 hypothetical protein -
BWR19_RS16930 3710675..3710806 - 132 WP_076749415.1 entericidin A/B family lipoprotein Toxin
BWR19_RS16935 3710934..3711065 - 132 WP_076750168.1 entericidin A/B family lipoprotein Antitoxin
BWR19_RS16940 3711171..3711596 + 426 WP_076749417.1 HIT family protein -
BWR19_RS16945 3711593..3712642 - 1050 WP_076749418.1 nickel/cobalt transporter -
BWR19_RS16950 3712630..3713307 - 678 WP_076750169.1 DUF1007 family protein -
BWR19_RS16955 3713358..3713729 - 372 WP_076749420.1 hypothetical protein -
BWR19_RS16960 3713726..3714316 - 591 WP_076749421.1 hypothetical protein -
BWR19_RS16965 3714447..3715583 + 1137 WP_076749423.1 glycerate kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 44 a.a.        Molecular weight: 4238.83 Da        Isoelectric Point: 4.2289

>T72253 WP_076749415.1 NZ_CP019326:c3710806-3710675 [Halomonas sp. 1513]
MKKAIALSFALLMAAGALAGCNTMDGAGQDVERGGEAVQDAAN

Download         Length: 132 bp

>T72253 NZ_CP019326:c3710806-3710675 [Halomonas sp. 1513]
ATGAAAAAAGCGATTGCCCTCAGTTTTGCCCTGCTCATGGCCGCTGGCGCCCTGGCGGGCTGCAACACCATGGACGGCGC
CGGCCAGGACGTCGAGCGCGGTGGTGAAGCGGTGCAGGATGCAGCCAACTAA

Antitoxin


Download         Length: 44 a.a.        Molecular weight: 4468.14 Da        Isoelectric Point: 4.6717

>AT72253 WP_076750168.1 NZ_CP019326:c3711065-3710934 [Halomonas sp. 1513]
MKRLSAAILLSLFTLSLLSGCNTMRGAGEDIEAGGEAIQRSAD

Download         Length: 132 bp

>AT72253 NZ_CP019326:c3711065-3710934 [Halomonas sp. 1513]
ATGAAACGGTTATCAGCTGCTATTCTACTCTCGCTGTTCACCCTGTCGCTGCTCAGCGGCTGTAACACCATGCGCGGTGC
AGGCGAGGATATCGAGGCGGGTGGAGAGGCCATTCAGCGCTCGGCGGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References