Detailed information of TA system TA072253

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): EcnAB/-
• Location: 3710675..3711065
• Replicon: chromosome
• Accession: NZ_CP019326
• Organism: Halomonas sp. 1513

Toxin (Protein)

• Gene name: EcnB
• Uniprot ID: -
• Locus tag: BWR19_RS16930
• Protein ID: WP_076749415.1
• Coordinates: 3710675..3710806 (-)
• Length: 44 a.a.

Antitoxin (Protein)

• Gene name: EcnA
• Uniprot ID: -
• Locus tag: BWR19_RS16935
• Protein ID: WP_076750168.1
• Coordinates: 3710934..3711065 (-)
• Length: 44 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BWR19_RS16905	3706593..3707120	+	528	WP_076749408.1	acyl-CoA thioesterase	-
BWR19_RS16910	3707155..3708150	+	996	WP_076749409.1	ion transporter	-
BWR19_RS16915	3708162..3709550	-	1389	WP_076749411.1	PLP-dependent aminotransferase family protein	-
BWR19_RS16920	3709646..3710251	+	606	WP_076749412.1	LysE family translocator	-
BWR19_RS16925	3710256..3710582	-	327	WP_076749414.1	hypothetical protein	-
BWR19_RS16930	3710675..3710806	-	132	WP_076749415.1	entericidin A/B family lipoprotein	Toxin
BWR19_RS16935	3710934..3711065	-	132	WP_076750168.1	entericidin A/B family lipoprotein	Antitoxin
BWR19_RS16940	3711171..3711596	+	426	WP_076749417.1	HIT family protein	-
BWR19_RS16945	3711593..3712642	-	1050	WP_076749418.1	nickel/cobalt transporter	-
BWR19_RS16950	3712630..3713307	-	678	WP_076750169.1	DUF1007 family protein	-
BWR19_RS16955	3713358..3713729	-	372	WP_076749420.1	hypothetical protein	-
BWR19_RS16960	3713726..3714316	-	591	WP_076749421.1	hypothetical protein	-
BWR19_RS16965	3714447..3715583	+	1137	WP_076749423.1	glycerate kinase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Entericidin A/B (23-42)

Antitoxin

• Entericidin A/B (23-42)

Sequences

Toxin

Protein

• Length: 44 a.a.
• Molecular weight: 4238.83 Da
• Isoelectric Point: 4.2289

>T72253 WP_076749415.1 NZ_CP019326:c3710806-3710675 [Halomonas sp. 1513]
MKKAIALSFALLMAAGALAGCNTMDGAGQDVERGGEAVQDAAN

Nucleotide

• Length: 132 bp

>T72253 NZ_CP019326:c3710806-3710675 [Halomonas sp. 1513]
ATGAAAAAAGCGATTGCCCTCAGTTTTGCCCTGCTCATGGCCGCTGGCGCCCTGGCGGGCTGCAACACCATGGACGGCGC
CGGCCAGGACGTCGAGCGCGGTGGTGAAGCGGTGCAGGATGCAGCCAACTAA

Antitoxin

Protein

• Length: 44 a.a.
• Molecular weight: 4468.14 Da
• Isoelectric Point: 4.6717

>AT72253 WP_076750168.1 NZ_CP019326:c3711065-3710934 [Halomonas sp. 1513]
MKRLSAAILLSLFTLSLLSGCNTMRGAGEDIEAGGEAIQRSAD

Nucleotide

• Length: 132 bp

>AT72253 NZ_CP019326:c3711065-3710934 [Halomonas sp. 1513]
ATGAAACGGTTATCAGCTGCTATTCTACTCTCGCTGTTCACCCTGTCGCTGCTCAGCGGCTGTAACACCATGCGCGGTGC
AGGCGAGGATATCGAGGCGGGTGGAGAGGCCATTCAGCGCTCGGCGGATTGA