Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 1635649..1636336 Replicon chromosome
Accession NZ_CP019326
Organism Halomonas sp. 1513

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag BWR19_RS07450 Protein ID WP_076747455.1
Coordinates 1635929..1636336 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag BWR19_RS07445 Protein ID WP_076747454.1
Coordinates 1635649..1635879 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BWR19_RS07425 1631439..1632107 + 669 WP_076747450.1 SPOR domain-containing protein -
BWR19_RS07430 1632107..1632706 + 600 WP_076747451.1 CvpA family protein -
BWR19_RS07435 1632790..1634310 + 1521 WP_076747452.1 amidophosphoribosyltransferase -
BWR19_RS07440 1634300..1635505 + 1206 WP_076747453.1 O-succinylhomoserine sulfhydrylase -
BWR19_RS07445 1635649..1635879 + 231 WP_076747454.1 antitoxin Antitoxin
BWR19_RS07450 1635929..1636336 + 408 WP_076747455.1 tRNA(fMet)-specific endonuclease VapC Toxin
BWR19_RS07455 1636418..1637440 + 1023 WP_198034560.1 sensor domain-containing diguanylate cyclase -
BWR19_RS07460 1637559..1638932 + 1374 WP_076747456.1 flagellar filament capping protein FliD -
BWR19_RS07465 1639072..1640436 + 1365 WP_076747457.1 flagellar filament capping protein FliD -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1634300..1644515 10215


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-123)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15012.22 Da        Isoelectric Point: 7.9466

>T72251 WP_076747455.1 NZ_CP019326:1635929-1636336 [Halomonas sp. 1513]
MLKYMLDTNICIFTIKNRPPQVRDTFKRHHAQLCISTVTLMELIYGAEKSASPERNLAVVEGFAARLEVLDYDAHAAAHS
GQIRAELAKSGTPIGPYDQMIAGHARSRGLVVVTHNIGEFQRVPGLRVENWTPDT

Download         Length: 408 bp

>T72251 NZ_CP019326:1635929-1636336 [Halomonas sp. 1513]
ATGTTGAAGTACATGCTGGACACCAACATCTGCATCTTCACCATCAAGAACCGCCCGCCACAGGTCCGCGATACCTTCAA
GCGTCATCATGCCCAGCTATGCATCAGTACCGTGACGCTGATGGAGTTGATCTACGGCGCCGAAAAATCGGCGAGCCCTG
AGCGTAACCTGGCGGTGGTTGAAGGCTTTGCCGCGCGCCTCGAGGTACTCGACTACGATGCCCATGCTGCAGCGCATAGC
GGGCAGATACGCGCTGAATTGGCCAAGAGTGGTACGCCCATTGGTCCATATGACCAGATGATCGCCGGCCATGCCCGATC
CCGAGGGCTTGTGGTGGTTACCCACAATATTGGTGAATTCCAACGTGTGCCTGGTCTCAGAGTCGAAAACTGGACGCCTG
ACACCTAG

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8411.34 Da        Isoelectric Point: 4.3719

>AT72251 WP_076747454.1 NZ_CP019326:1635649-1635879 [Halomonas sp. 1513]
MEQASVFKSNRSQAVRLPKAAALPDSVTRVDVVVVGRTRIIAPAGEAWDSWFDGETVSDDYMLERGQPADQEREGF

Download         Length: 231 bp

>AT72251 NZ_CP019326:1635649-1635879 [Halomonas sp. 1513]
ATGGAACAGGCATCGGTATTCAAGAGCAATCGCAGCCAGGCAGTTCGGCTGCCCAAGGCCGCCGCTCTGCCCGACAGCGT
CACTCGCGTCGACGTGGTAGTGGTGGGGCGGACGCGCATTATCGCCCCGGCAGGCGAAGCCTGGGACAGCTGGTTCGATG
GCGAAACCGTTAGCGACGACTACATGCTCGAGCGCGGCCAGCCGGCCGACCAAGAGCGTGAGGGGTTTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References