Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RelE-Phd |
Location | 29108..29667 | Replicon | chromosome |
Accession | NZ_CP019304 | ||
Organism | Arthrobacter sp. QXT-31 |
Toxin (Protein)
Gene name | relE | Uniprot ID | - |
Locus tag | BWQ92_RS00150 | Protein ID | WP_083706412.1 |
Coordinates | 29395..29667 (+) | Length | 91 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | - |
Locus tag | BWQ92_RS00145 | Protein ID | WP_076797708.1 |
Coordinates | 29108..29383 (+) | Length | 92 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
BWQ92_RS00125 | 24780..25160 | - | 381 | Protein_26 | IS701 family transposase | - |
BWQ92_RS00130 | 25770..26630 | - | 861 | WP_076797705.1 | alpha/beta hydrolase | - |
BWQ92_RS00135 | 26649..27056 | - | 408 | WP_076797706.1 | hypothetical protein | - |
BWQ92_RS00140 | 27274..28236 | + | 963 | WP_076797707.1 | LysR family transcriptional regulator | - |
BWQ92_RS00145 | 29108..29383 | + | 276 | WP_076797708.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
BWQ92_RS00150 | 29395..29667 | + | 273 | WP_083706412.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
BWQ92_RS00155 | 30028..30678 | - | 651 | WP_083706413.1 | TetR/AcrR family transcriptional regulator | - |
BWQ92_RS00160 | 31343..32167 | + | 825 | WP_157365252.1 | alpha/beta hydrolase | - |
BWQ92_RS00165 | 32584..32937 | + | 354 | WP_076797710.1 | metalloregulator ArsR/SmtB family transcription factor | - |
BWQ92_RS00170 | 32885..33391 | + | 507 | WP_172804229.1 | SRPBCC domain-containing protein | - |
BWQ92_RS00175 | 33388..34143 | + | 756 | WP_076797712.1 | alpha/beta hydrolase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10385.01 Da Isoelectric Point: 10.1326
>T72231 WP_083706412.1 NZ_CP019304:29395-29667 [Arthrobacter sp. QXT-31]
IQDPWKVEVTSPALKGFRRLPEKAAAAIVEFVTGVLSENPYRLSKPLTNELLGLRTARRGDYRVLFTLDVEAHILYVHRI
EHRSDVYKPR
IQDPWKVEVTSPALKGFRRLPEKAAAAIVEFVTGVLSENPYRLSKPLTNELLGLRTARRGDYRVLFTLDVEAHILYVHRI
EHRSDVYKPR
Download Length: 273 bp
>T72231 NZ_CP019304:29395-29667 [Arthrobacter sp. QXT-31]
ATCCAAGATCCATGGAAGGTTGAAGTCACCAGCCCGGCACTGAAGGGCTTCCGGCGGCTGCCGGAGAAAGCGGCCGCCGC
CATCGTCGAGTTCGTCACCGGAGTCCTGTCCGAGAACCCGTACCGGTTGAGCAAGCCCTTGACGAACGAACTTCTCGGCC
TGCGCACCGCACGACGCGGTGACTACAGGGTACTGTTCACCCTCGACGTTGAAGCCCACATCCTCTACGTTCACCGCATC
GAACACCGCTCGGACGTCTACAAACCCCGATAG
ATCCAAGATCCATGGAAGGTTGAAGTCACCAGCCCGGCACTGAAGGGCTTCCGGCGGCTGCCGGAGAAAGCGGCCGCCGC
CATCGTCGAGTTCGTCACCGGAGTCCTGTCCGAGAACCCGTACCGGTTGAGCAAGCCCTTGACGAACGAACTTCTCGGCC
TGCGCACCGCACGACGCGGTGACTACAGGGTACTGTTCACCCTCGACGTTGAAGCCCACATCCTCTACGTTCACCGCATC
GAACACCGCTCGGACGTCTACAAACCCCGATAG
Antitoxin
Download Length: 92 a.a. Molecular weight: 10169.39 Da Isoelectric Point: 4.8994
>AT72231 WP_076797708.1 NZ_CP019304:29108-29383 [Arthrobacter sp. QXT-31]
MKTVPLSEAKDKLSALVEEADKTHEIIQITRHGHPSAVLMSAEDLESLQETIHWLSQPGIREDLAQARRDIAEGNTTSGE
DLRREFGLPPR
MKTVPLSEAKDKLSALVEEADKTHEIIQITRHGHPSAVLMSAEDLESLQETIHWLSQPGIREDLAQARRDIAEGNTTSGE
DLRREFGLPPR
Download Length: 276 bp
>AT72231 NZ_CP019304:29108-29383 [Arthrobacter sp. QXT-31]
ATGAAGACGGTACCGCTTAGTGAAGCGAAGGACAAGCTTTCCGCGCTCGTGGAGGAAGCGGACAAGACACACGAGATCAT
CCAGATCACCCGACACGGGCACCCCTCAGCGGTCCTGATGTCCGCCGAGGACCTGGAATCCCTGCAGGAAACCATCCATT
GGCTGTCGCAACCGGGCATCCGTGAAGACCTGGCCCAGGCCAGACGCGATATCGCGGAGGGAAACACAACCAGCGGAGAA
GACCTCCGCCGCGAATTCGGGCTCCCGCCGCGGTGA
ATGAAGACGGTACCGCTTAGTGAAGCGAAGGACAAGCTTTCCGCGCTCGTGGAGGAAGCGGACAAGACACACGAGATCAT
CCAGATCACCCGACACGGGCACCCCTCAGCGGTCCTGATGTCCGCCGAGGACCTGGAATCCCTGCAGGAAACCATCCATT
GGCTGTCGCAACCGGGCATCCGTGAAGACCTGGCCCAGGCCAGACGCGATATCGCGGAGGGAAACACAACCAGCGGAGAA
GACCTCCGCCGCGAATTCGGGCTCCCGCCGCGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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