Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2822533..2822804 Replicon chromosome
Accession NZ_CP019250
Organism Escherichia coli strain 13KWH46

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2822663..2822766 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2822533..2822804 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BWI84_RS14580 2819088..2819750 - 663 WP_000944256.1 exodeoxyribonuclease X -
BWI84_RS14585 2819774..2820430 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
BWI84_RS14590 2820532..2820762 - 231 WP_000916763.1 DNA polymerase III subunit theta -
BWI84_RS14595 2820901..2821275 + 375 WP_000204699.1 CopC domain-containing protein YobA -
BWI84_RS14600 2821279..2822151 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
BWI84_RS14605 2822164..2822505 + 342 WP_000976472.1 YebY family protein -
- 2822533..2822804 - 272 - - Antitoxin
- 2822663..2822766 + 104 - - Toxin
BWI84_RS14610 2822901..2823557 + 657 WP_000812735.1 protein-serine/threonine phosphatase -
BWI84_RS14615 2823558..2823749 - 192 WP_001296140.1 YebW family protein -
BWI84_RS14620 2823854..2824090 - 237 WP_148116966.1 DUF1480 family protein -
BWI84_RS14625 2824208..2825647 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T71979 NZ_CP019250:2822663-2822766 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT71979 NZ_CP019250:c2822804-2822533 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References