Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3681183..3681454 Replicon chromosome
Accession NZ_CP019245
Organism Escherichia coli strain Combat13F7

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3681313..3681416 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3681183..3681454 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BWI83_RS18730 3677738..3678400 - 663 WP_000944256.1 exodeoxyribonuclease X -
BWI83_RS18735 3678424..3679080 - 657 WP_000011656.1 carbon-nitrogen hydrolase family protein -
BWI83_RS18740 3679182..3679412 - 231 WP_000916763.1 DNA polymerase III subunit theta -
BWI83_RS18745 3679551..3679925 + 375 WP_000255065.1 CopC domain-containing protein YobA -
BWI83_RS18750 3679929..3680801 + 873 WP_088213340.1 copper homeostasis membrane protein CopD -
BWI83_RS18755 3680814..3681155 + 342 WP_000976472.1 YebY family protein -
- 3681183..3681454 - 272 - - Antitoxin
- 3681313..3681416 + 104 - - Toxin
BWI83_RS18760 3681551..3682072 + 522 Protein_3402 protein-serine/threonine phosphatase -
BWI83_RS18770 3683369..3683521 + 153 Protein_3404 serine/threonine-protein phosphatase -
BWI83_RS18775 3683522..3683713 - 192 WP_001338167.1 YebW family protein -
BWI83_RS18780 3683818..3684054 - 237 WP_001338166.1 DUF1480 family protein -
BWI83_RS18785 3684172..3685611 - 1440 WP_001338165.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3675681..3688324 12643


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T71951 NZ_CP019245:3681313-3681416 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT71951 NZ_CP019245:c3681454-3681183 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References