Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 647567..647835 Replicon chromosome
Accession NZ_CP019243
Organism Escherichia coli strain Combat2C1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 647605..647707 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 647567..647835 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BWI82_RS03495 644724..646163 + 1440 WP_001298454.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
BWI82_RS03500 646281..646517 + 237 WP_001295499.1 DUF1480 family protein -
BWI82_RS03505 646622..646813 + 192 WP_001296140.1 YebW family protein -
BWI82_RS03510 646814..647470 - 657 WP_000812743.1 protein-serine/threonine phosphatase -
- 647567..647835 + 269 - - Antitoxin
- 647605..647707 - 103 - - Toxin
BWI82_RS03515 647865..648206 - 342 WP_000984819.1 YebY family protein -
BWI82_RS03520 648219..649091 - 873 WP_000879311.1 copper homeostasis membrane protein CopD -
BWI82_RS03525 649095..649469 - 375 WP_000168747.1 CopC domain-containing protein YobA -
BWI82_RS03530 649608..649838 + 231 WP_000916763.1 DNA polymerase III subunit theta -
BWI82_RS03535 649941..650597 + 657 WP_000011644.1 carbon-nitrogen hydrolase family protein -
BWI82_RS03540 650621..651283 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 639337..726414 87077


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T71906 NZ_CP019243:c647707-647605 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT71906 NZ_CP019243:647567-647835 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References