Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 3716354..3716865 Replicon chromosome
Accession NZ_CP019240
Organism Rhodoferax antarcticus strain DSMZ24876

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag RA876_RS18030 Protein ID WP_075585376.1
Coordinates 3716354..3716617 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag RA876_RS18035 Protein ID WP_075585377.1
Coordinates 3716614..3716865 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RA876_RS17995 3711427..3711651 - 225 WP_075585582.1 MerR family transcriptional regulator -
RA876_RS18000 3711946..3712455 + 510 WP_075585371.1 pilin -
RA876_RS18005 3712496..3714178 + 1683 WP_075585372.1 O-antigen ligase family protein -
RA876_RS18010 3714269..3715048 + 780 WP_075585373.1 pilus assembly protein -
RA876_RS18015 3715416..3715736 - 321 WP_075585374.1 type II toxin-antitoxin system RelE/ParE family toxin -
RA876_RS18020 3715736..3716014 - 279 WP_075585375.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
RA876_RS18025 3716141..3716224 + 84 Protein_3526 transposase -
RA876_RS18030 3716354..3716617 - 264 WP_075585376.1 Txe/YoeB family addiction module toxin Toxin
RA876_RS18035 3716614..3716865 - 252 WP_075585377.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
RA876_RS18040 3716981..3717433 - 453 WP_075585378.1 DUF2442 domain-containing protein -
RA876_RS18045 3717430..3717660 - 231 WP_075585379.1 DUF4160 domain-containing protein -
RA876_RS18050 3718072..3718449 + 378 WP_075585380.1 type II toxin-antitoxin system RelE/ParE family toxin -
RA876_RS18055 3718430..3718765 + 336 WP_075585381.1 helix-turn-helix domain-containing protein -
RA876_RS18060 3718830..3719522 + 693 WP_075585382.1 transposase -
RA876_RS18065 3719968..3721554 + 1587 WP_075585383.1 O-antigen ligase C-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10061.40 Da        Isoelectric Point: 8.0799

>T71901 WP_075585376.1 NZ_CP019240:c3716617-3716354 [Rhodoferax antarcticus]
MRGVLFVGAVWADDVDWQGQDKKTLKRINLLIESARRTPFEGIGKPEPLLGNLSGYWSRRIDDTHRLVYRATDDNLHIVS
CRHHYDA

Download         Length: 264 bp

>T71901 NZ_CP019240:c3716617-3716354 [Rhodoferax antarcticus]
ATGAGGGGCGTTCTTTTCGTTGGTGCGGTGTGGGCCGATGACGTTGACTGGCAGGGGCAGGATAAAAAGACTTTGAAGCG
TATCAATCTACTCATCGAATCAGCACGGCGTACACCGTTCGAGGGCATAGGCAAACCTGAACCACTGCTGGGCAACTTAT
CCGGCTACTGGTCCCGCCGGATAGATGATACGCACCGGCTGGTGTACCGTGCCACTGATGACAACTTGCACATCGTTTCA
TGTCGCCACCACTATGATGCTTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8967.22 Da        Isoelectric Point: 6.2068

>AT71901 WP_075585377.1 NZ_CP019240:c3716865-3716614 [Rhodoferax antarcticus]
MNVVTYSEARSSLKAVLDRVVNDHAPTLIHRRGGNVVIVSEDAYSSMVETMYLLSNPANAAHLAMAIAQDKAGESKPQTL
IEV

Download         Length: 252 bp

>AT71901 NZ_CP019240:c3716865-3716614 [Rhodoferax antarcticus]
ATGAATGTCGTGACCTACTCCGAAGCTCGAAGCTCACTCAAAGCAGTGCTTGACCGTGTTGTTAACGACCACGCACCCAC
CCTCATTCACCGACGCGGCGGCAATGTTGTCATCGTGTCAGAGGATGCCTATTCGAGCATGGTTGAAACCATGTACCTGC
TATCCAACCCAGCCAATGCAGCGCACTTGGCCATGGCGATAGCGCAGGACAAGGCCGGGGAGTCCAAACCGCAAACGCTG
ATCGAGGTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References