Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 3345926..3346614 Replicon chromosome
Accession NZ_CP019240
Organism Rhodoferax antarcticus strain DSMZ24876

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag RA876_RS16245 Protein ID WP_075585196.1
Coordinates 3346183..3346614 (+) Length 144 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag RA876_RS16240 Protein ID WP_075585055.1
Coordinates 3345926..3346165 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RA876_RS16200 3341166..3341540 + 375 WP_075585049.1 hypothetical protein -
RA876_RS16205 3341613..3342158 - 546 WP_075585195.1 phasin family protein -
RA876_RS16210 3342315..3343211 - 897 WP_075585050.1 DMT family transporter -
RA876_RS16215 3343331..3344194 - 864 WP_075585051.1 creatininase family protein -
RA876_RS16220 3344237..3344584 - 348 WP_075585052.1 alkylphosphonate utilization protein -
RA876_RS16225 3344547..3345245 - 699 Protein_3172 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
RA876_RS16235 3345255..3345749 - 495 WP_139313284.1 helix-turn-helix domain-containing protein -
RA876_RS16240 3345926..3346165 + 240 WP_075585055.1 hypothetical protein Antitoxin
RA876_RS16245 3346183..3346614 + 432 WP_075585196.1 PIN domain-containing protein Toxin
RA876_RS16250 3346669..3347490 + 822 WP_075585197.1 alanyl-tRNA editing protein -
RA876_RS16255 3347487..3347831 + 345 WP_075585056.1 DUF167 domain-containing protein -
RA876_RS16260 3347897..3350068 + 2172 WP_075585057.1 RNB domain-containing ribonuclease -
RA876_RS16265 3350056..3350922 + 867 WP_075585058.1 TonB family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-128)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 144 a.a.        Molecular weight: 15445.83 Da        Isoelectric Point: 6.4860

>T71900 WP_075585196.1 NZ_CP019240:3346183-3346614 [Rhodoferax antarcticus]
VRLLLDVNVWIALLDDAHVHNAEALALFQKPGLKIATCPLVENGVLRVLNLPGYSQHGPAGFEAVRAKLALACGDVDHAF
WSDDVSLRTDGLVNWSRVFGHGQITDLYLLTLAVAHQGALATFDHRIALNAVVGAEKSHLLLL

Download         Length: 432 bp

>T71900 NZ_CP019240:3346183-3346614 [Rhodoferax antarcticus]
GTGCGTTTGCTGCTGGACGTCAACGTCTGGATTGCGCTGCTCGACGATGCACACGTCCACAATGCCGAAGCACTGGCCCT
CTTTCAAAAACCCGGTCTCAAAATTGCCACCTGCCCGCTGGTGGAAAACGGTGTGCTGCGCGTGCTGAACCTGCCCGGCT
ACAGCCAGCATGGCCCGGCAGGGTTTGAAGCCGTGCGCGCCAAGTTGGCCCTGGCCTGTGGGGATGTCGATCACGCTTTT
TGGTCCGACGATGTCAGTCTGCGCACCGATGGCCTGGTGAACTGGAGCCGGGTGTTCGGGCACGGCCAGATCACCGACCT
GTACCTGCTGACTCTGGCCGTAGCGCACCAAGGCGCACTAGCCACGTTTGATCACCGGATTGCCTTGAATGCCGTGGTTG
GAGCCGAGAAGTCGCACTTACTTCTTTTGTGA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8911.09 Da        Isoelectric Point: 9.9619

>AT71900 WP_075585055.1 NZ_CP019240:3345926-3346165 [Rhodoferax antarcticus]
MRTTLSLDDDVFAVARQRAQRERTSLGEAVSRYVRDALRANAQAPATPAVLRSKYSVLPARDEIITTEHVRRLMDQEGI

Download         Length: 240 bp

>AT71900 NZ_CP019240:3345926-3346165 [Rhodoferax antarcticus]
ATGCGCACCACCCTGTCCCTGGACGACGATGTTTTTGCGGTCGCTCGCCAGCGTGCCCAGCGCGAGCGCACTTCCTTGGG
CGAGGCGGTGTCGCGCTACGTGCGCGATGCCTTGCGCGCCAATGCCCAGGCGCCCGCGACCCCGGCTGTTTTGCGCAGCA
AGTATTCGGTGCTGCCAGCGCGGGATGAAATCATCACCACGGAACACGTTCGCCGCCTGATGGATCAGGAGGGGATTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References