Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2970282..2970883 Replicon chromosome
Accession NZ_CP019240
Organism Rhodoferax antarcticus strain DSMZ24876

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag RA876_RS14305 Protein ID WP_075584728.1
Coordinates 2970587..2970883 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag RA876_RS14300 Protein ID WP_075584727.1
Coordinates 2970282..2970590 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RA876_RS14290 2966659..2969832 - 3174 WP_075584725.1 type I restriction endonuclease subunit R -
RA876_RS14295 2969950..2970249 - 300 WP_173861816.1 helix-turn-helix domain-containing protein -
RA876_RS14300 2970282..2970590 - 309 WP_075584727.1 putative addiction module antidote protein Antitoxin
RA876_RS14305 2970587..2970883 - 297 WP_075584728.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
RA876_RS14310 2971039..2972409 - 1371 WP_075584729.1 restriction endonuclease subunit S -
RA876_RS14315 2972406..2974148 - 1743 WP_075584730.1 type I restriction-modification system subunit M -
RA876_RS14320 2974235..2974699 + 465 WP_075584731.1 terminase small subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2961504..2980079 18575


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-95)

Antitoxin

Cro/C1-type helix-turn-helix domain

(38-87)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11106.87 Da        Isoelectric Point: 10.2720

>T71899 WP_075584728.1 NZ_CP019240:c2970883-2970587 [Rhodoferax antarcticus]
MYTVIETDTFQSWVDSLRDMPTRIRLRRRLGKAMRGNLGDVKAVGDGVWEMREFFGPGWRLYYVQRGDVLIVMLGGGDKS
SQGRDIAAAKVLAKEINL

Download         Length: 297 bp

>T71899 NZ_CP019240:c2970883-2970587 [Rhodoferax antarcticus]
ATGTACACCGTCATTGAAACCGATACCTTTCAAAGCTGGGTGGACAGTTTGCGCGATATGCCAACTCGCATTCGTTTGCG
GCGTCGGCTGGGTAAGGCGATGCGGGGCAATCTGGGTGATGTCAAAGCTGTGGGTGATGGCGTTTGGGAAATGCGCGAGT
TTTTCGGCCCCGGTTGGCGTTTGTACTACGTGCAGCGCGGCGACGTGCTGATTGTCATGTTGGGCGGCGGCGACAAGTCC
AGCCAGGGGCGGGACATTGCCGCAGCCAAAGTTCTGGCCAAAGAGATCAATTTATGA

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11002.45 Da        Isoelectric Point: 4.7719

>AT71899 WP_075584727.1 NZ_CP019240:c2970590-2970282 [Rhodoferax antarcticus]
MSTIKTRPFDMANYLTNAEEVTEYLRQVLEDGDPVELGAALGDIARARGMTQLARDTGLSRESLYKSLSGERAPNSDTLF
KVIRALGFQLTLASAAPAAPAQ

Download         Length: 309 bp

>AT71899 NZ_CP019240:c2970590-2970282 [Rhodoferax antarcticus]
ATGAGCACCATCAAAACACGGCCATTCGACATGGCCAACTACCTCACCAACGCCGAGGAGGTGACCGAATACCTGCGCCA
AGTGCTGGAAGACGGTGACCCGGTAGAACTGGGCGCTGCCTTGGGGGACATTGCCCGCGCACGTGGCATGACCCAGTTGG
CACGCGACACCGGTTTGTCGCGCGAAAGCCTGTACAAAAGCCTCTCCGGCGAGCGAGCACCCAACTCAGACACGCTGTTC
AAGGTGATACGGGCGCTGGGCTTTCAGCTCACTCTAGCGTCGGCAGCACCTGCGGCACCGGCGCAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References